1305 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | 3/4(17) |
265 | GO:0000166 | nucleotide binding | 3/11(42) |
1263 | GO:0016787 | hydrolase activity | 1/4(17) |
1263 | GO:0004806 | triglyceride lipase activity | 1/4(17) |
3497 | GO:0046872 | metal ion binding | 2/2(9) |
9546 | GO:0016787 | hydrolase activity | 1/2(4) |
9546 | GO:0008768 | UDP-sugar diphosphatase activity | 1/2(4) |
218 | GO:0016020 | membrane | 3/13(48) |
218 | GO:0004745 | retinol dehydrogenase activity | 2/13(48) |
873 | GO:0005078 | MAP-kinase scaffold activity | 1/4(23) |
2954 | GO:0008465 | glycerate dehydrogenase activity | 2/2(9) |
499 | GO:0005096 | GTPase activator activity | 2/6(29) |
468 | GO:0005319 | lipid transporter activity | 4/10(31) |
165 | GO:0003677 | DNA binding | 20/24(57) |
8782 | GO:0016020 | membrane | 1/2(6) |
9632 | GO:0016020 | membrane | 1/1(4) |
3345 | GO:0005509 | calcium ion binding | 2/2(9) |
490 | GO:0003950 | NAD+ ADP-ribosyltransferase activity | 2/7(30) |
490 | GO:0004842 | ubiquitin-protein transferase activity | 1/7(30) |
493 | GO:0002009 | morphogenesis of an epithelium | 2/6(29) |
493 | GO:0005509 | calcium ion binding | 1/6(29) |
493 | GO:0007154 | cell communication | 1/6(29) |
24 | GO:0008233 | peptidase activity | 2/54(230) |
24 | GO:0004175 | endopeptidase activity | 4/54(230) |
24 | GO:0004222 | metalloendopeptidase activity | 16/54(230) |
26 | GO:0005200 | structural constituent of cytoskeleton | 54/166(216) |
27 | GO:0000166 | nucleotide binding | 15/49(188) |
27 | GO:0000287 | magnesium ion binding | 3/49(188) |
27 | GO:0002039 | p53 binding | 1/49(188) |
27 | GO:0004674 | protein serine/threonine kinase activity | 1/49(188) |
27 | GO:0004672 | protein kinase activity | 5/49(188) |
1543 | GO:0003824 | catalytic activity | 1/5(16) |
2361 | GO:0046872 | metal ion binding | 1/2(12) |
23 | GO:0000287 | magnesium ion binding | 2/61(232) |
23 | GO:0004672 | protein kinase activity | 17/61(232) |
23 | GO:0000166 | nucleotide binding | 18/61(232) |
699 | GO:0000166 | nucleotide binding | 2/4(25) |
29 | GO:0001756 | somitogenesis | 1/44(182) |
29 | GO:0035064 | methylated histone binding | 2/44(182) |
29 | GO:0030332 | cyclin binding | 1/44(182) |
29 | GO:0003700 | transcription factor activity, sequence-specific DNA binding | 1/44(182) |
29 | GO:0008017 | microtubule binding | 4/44(182) |
29 | GO:0003713 | transcription coactivator activity | 2/44(182) |
29 | GO:0003431 | growth plate cartilage chondrocyte development | 1/44(182) |
29 | GO:0005198 | structural molecule activity | 2/44(182) |
29 | GO:0006364 | rRNA processing | 1/44(182) |
29 | GO:0019904 | protein domain specific binding | 3/44(182) |
29 | GO:0008168 | methyltransferase activity | 1/44(182) |
29 | GO:0001895 | retina homeostasis | 1/44(182) |
29 | GO:0004842 | ubiquitin-protein transferase activity | 3/44(182) |
29 | GO:0044822 | poly(A) RNA binding | 1/44(182) |
29 | GO:0008270 | zinc ion binding | 2/44(182) |
7612 | GO:0005125 | cytokine activity | 2/2(8) |
222 | GO:0005509 | calcium ion binding | 3/8(48) |
543 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 1/5(28) |
2156 | GO:0016020 | membrane | 1/2(14) |
404 | GO:0003676 | nucleic acid binding | 3/7(33) |
2248 | GO:0016020 | membrane | 1/3(13) |
162 | GO:0005216 | ion channel activity | 1/9(57) |
162 | GO:0006816 | calcium ion transport | 1/9(57) |
3804 | GO:0019901 | protein kinase binding | 2/2(9) |
933 | GO:0016567 | protein ubiquitination | 2/7(22) |
933 | GO:0035556 | intracellular signal transduction | 1/7(22) |
280 | GO:0044325 | ion channel binding | 1/7(40) |
283 | GO:0006810 | transport | 3/10(40) |
283 | GO:0015485 | cholesterol binding | 3/10(40) |
2240 | GO:0016020 | membrane | 1/4(13) |
2241 | GO:0016787 | hydrolase activity | 1/3(13) |
1672 | GO:0008140 | cAMP response element binding protein binding | 2/4(16) |
1094 | GO:0005509 | calcium ion binding | 2/4(19) |
869 | GO:0043237 | laminin-1 binding | 2/7(23) |
869 | GO:0005576 | extracellular region | 2/7(23) |
1083 | GO:0003824 | catalytic activity | 4/4(19) |
739 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity | 1/6(24) |
1158 | GO:0016798 | hydrolase activity, acting on glycosyl bonds | 2/4(18) |
2297 | GO:0016020 | membrane | 2/2(13) |
967 | GO:0003993 | acid phosphatase activity | 3/6(21) |
2468 | GO:0003676 | nucleic acid binding | 1/2(11) |
1150 | GO:0003779 | actin binding | 2/2(18) |
2703 | GO:0044822 | poly(A) RNA binding | 1/2(10) |
121 | GO:0002091 | negative regulation of receptor internalization | 3/17(74) |
121 | GO:0016020 | membrane | 1/17(74) |
121 | GO:0060348 | bone development | 2/17(74) |
121 | GO:0051965 | positive regulation of synapse assembly | 1/17(74) |
121 | GO:0005518 | collagen binding | 1/17(74) |
121 | GO:0001530 | lipopolysaccharide binding | 1/17(74) |
121 | GO:0001968 | fibronectin binding | 1/17(74) |
1492 | GO:0003735 | structural constituent of ribosome | 2/5(17) |
260 | GO:0005244 | voltage-gated ion channel activity | 3/11(42) |
260 | GO:0004602 | glutathione peroxidase activity | 2/11(42) |
124 | GO:0000166 | nucleotide binding | 12/14(73) |
9078 | GO:0033617 | mitochondrial respiratory chain complex IV assembly | 1/2(6) |
126 | GO:0008146 | sulfotransferase activity | 11/19(71) |
264 | GO:0004871 | signal transducer activity | 10/12(42) |
138 | GO:0014719 | skeletal muscle satellite cell activation | 2/12(64) |
138 | GO:0005509 | calcium ion binding | 1/12(64) |
9475 | GO:0008121 | ubiquinol-cytochrome-c reductase activity | 3/3(4) |
2499 | GO:0005154 | epidermal growth factor receptor binding | 1/2(11) |
1068 | GO:0008270 | zinc ion binding | 2/4(19) |
1702 | GO:0004871 | signal transducer activity | 4/4(16) |
1557 | GO:0004720 | protein-lysine 6-oxidase activity | 1/3(16) |
3565 | GO:0016403 | dimethylargininase activity | 1/2(9) |
54 | GO:0000166 | nucleotide binding | 20/33(131) |
584 | GO:0004415 | hyalurononglucosaminidase activity | 2/7(27) |
584 | GO:0098641 | cadherin binding involved in cell-cell adhesion | 2/7(27) |
1062 | GO:0098641 | cadherin binding involved in cell-cell adhesion | 1/6(19) |
1062 | GO:0005615 | extracellular space | 2/6(19) |
53 | GO:0000975 | regulatory region DNA binding | 1/39(133) |
53 | GO:0001972 | retinoic acid binding | 1/39(133) |
53 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 1/39(133) |
53 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 6/39(133) |
53 | GO:0001046 | core promoter sequence-specific DNA binding | 2/39(133) |
53 | GO:0003677 | DNA binding | 9/39(133) |
53 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 4/39(133) |
53 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3/39(133) |
1066 | GO:0003735 | structural constituent of ribosome | 1/3(19) |
1066 | GO:0006396 | RNA processing | 1/3(19) |
2145 | GO:0004672 | protein kinase activity | 1/3(14) |
16 | GO:0003676 | nucleic acid binding | 14/69(264) |
16 | GO:0000166 | nucleotide binding | 25/69(264) |
2415 | GO:0016020 | membrane | 4/5(11) |
427 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2/7(32) |
427 | GO:0003676 | nucleic acid binding | 3/7(32) |
860 | GO:0007165 | signal transduction | 1/4(23) |
825 | GO:0005096 | GTPase activator activity | 2/6(23) |
825 | GO:0007165 | signal transduction | 1/6(23) |
825 | GO:0002011 | morphogenesis of an epithelial sheet | 1/6(23) |
297 | GO:0005096 | GTPase activator activity | 3/8(39) |
294 | GO:0003677 | DNA binding | 3/9(39) |
372 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/7(34) |
372 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1/7(34) |
372 | GO:0000975 | regulatory region DNA binding | 2/7(34) |
2253 | GO:0004842 | ubiquitin-protein transferase activity | 1/2(13) |
2493 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2/2(11) |
539 | GO:0003677 | DNA binding | 3/8(28) |
822 | GO:0007165 | signal transduction | 1/5(23) |
9263 | GO:0000045 | autophagosome assembly | 2/2(5) |
590 | GO:0008270 | zinc ion binding | 4/7(27) |
2492 | GO:0003824 | catalytic activity | 1/2(11) |
708 | GO:0008017 | microtubule binding | 3/5(24) |
708 | GO:0005622 | intracellular | 1/5(24) |
135 | GO:0000155 | phosphorelay sensor kinase activity | 3/15(65) |
135 | GO:0005216 | ion channel activity | 1/15(65) |
147 | GO:0019901 | protein kinase binding | 1/12(61) |
147 | GO:0016020 | membrane | 3/12(61) |
147 | GO:0030220 | platelet formation | 1/12(61) |
599 | GO:0006461 | protein complex assembly | 2/6(26) |
598 | GO:0007612 | learning | 1/7(26) |
134 | GO:0000166 | nucleotide binding | 8/14(66) |
986 | GO:0016020 | membrane | 2/5(21) |
986 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 1/5(21) |
8514 | GO:0019902 | phosphatase binding | 1/2(6) |
193 | GO:0003677 | DNA binding | 1/14(51) |
193 | GO:0000166 | nucleotide binding | 4/14(51) |
1088 | GO:0004721 | phosphoprotein phosphatase activity | 1/5(19) |
8444 | GO:0010629 | negative regulation of gene expression | 1/1(7) |
271 | GO:0005178 | integrin binding | 1/9(41) |
271 | GO:0005509 | calcium ion binding | 2/9(41) |
271 | GO:0001968 | fibronectin binding | 2/9(41) |
271 | GO:0005006 | epidermal growth factor-activated receptor activity | 2/9(41) |
273 | GO:0000975 | regulatory region DNA binding | 1/7(41) |
273 | GO:0003677 | DNA binding | 4/7(41) |
9656 | GO:0003735 | structural constituent of ribosome | 2/2(4) |
3148 | GO:0051082 | unfolded protein binding | 2/2(9) |
2364 | GO:0008270 | zinc ion binding | 2/2(12) |
80 | GO:0005215 | transporter activity | 7/26(103) |
52 | GO:0005242 | inward rectifier potassium channel activity | 21/35(134) |
119 | GO:0016787 | hydrolase activity | 4/22(75) |
119 | GO:0042043 | neurexin family protein binding | 4/22(75) |
119 | GO:0003990 | acetylcholinesterase activity | 2/22(75) |
119 | GO:0004771 | sterol esterase activity | 1/22(75) |
8526 | GO:0061630 | ubiquitin protein ligase activity | 1/2(6) |
1233 | GO:0006464 | cellular protein modification process | 1/5(18) |
9714 | GO:0005525 | GTP binding | 1/1(4) |
9633 | GO:0003735 | structural constituent of ribosome | 2/2(4) |
2099 | GO:0016020 | membrane | 3/4(14) |
2302 | GO:0006904 | vesicle docking involved in exocytosis | 1/4(13) |
894 | GO:0003676 | nucleic acid binding | 2/4(22) |
1856 | GO:0008270 | zinc ion binding | 1/2(16) |
798 | GO:0016020 | membrane | 1/6(24) |
798 | GO:0005254 | chloride channel activity | 1/6(24) |
300 | GO:0008092 | cytoskeletal protein binding | 1/7(38) |
3 | GO:0000287 | magnesium ion binding | 1/139(535) |
3 | GO:0000166 | nucleotide binding | 72/139(535) |
3 | GO:0003779 | actin binding | 2/139(535) |
3 | GO:0004713 | protein tyrosine kinase activity | 1/139(535) |
3 | GO:0004672 | protein kinase activity | 11/139(535) |
3 | GO:0005524 | ATP binding | 1/139(535) |
918 | GO:0016020 | membrane | 1/4(22) |
918 | GO:0001525 | angiogenesis | 1/4(22) |
369 | GO:0008198 | ferrous iron binding | 1/6(34) |
915 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2/5(22) |
914 | GO:0005102 | receptor binding | 3/4(22) |
170 | GO:0006955 | immune response | 5/24(57) |
7737 | GO:0008455 | alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity | 1/2(7) |
529 | GO:0000166 | nucleotide binding | 7/7(28) |
1012 | GO:0003713 | transcription coactivator activity | 1/3(20) |
1012 | GO:0000398 | mRNA splicing, via spliceosome | 1/3(20) |
426 | GO:0008270 | zinc ion binding | 1/6(32) |
309 | GO:0016020 | membrane | 1/7(38) |
309 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity | 2/7(38) |
2769 | GO:0006810 | transport | 1/2(10) |
2760 | GO:0005509 | calcium ion binding | 1/2(10) |
425 | GO:0008375 | acetylglucosaminyltransferase activity | 3/5(32) |
425 | GO:0015020 | glucuronosyltransferase activity | 1/5(32) |
9150 | GO:0016020 | membrane | 2/2(5) |
581 | GO:0051497 | negative regulation of stress fiber assembly | 1/7(27) |
581 | GO:0045202 | synapse | 3/7(27) |
1133 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 3/4(18) |
1130 | GO:0016020 | membrane | 2/4(18) |
446 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity | 1/4(32) |
2765 | GO:0000166 | nucleotide binding | 1/2(10) |
305 | GO:0015020 | glucuronosyltransferase activity | 1/17(38) |
381 | GO:0000166 | nucleotide binding | 2/5(33) |
382 | GO:0000831 | inositol hexakisphosphate 6-kinase activity | 1/9(33) |
382 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity | 4/9(33) |
6005 | GO:0004108 | citrate (Si)-synthase activity | 1/1(8) |
9002 | GO:0016020 | membrane | 1/2(6) |
243 | GO:0005509 | calcium ion binding | 1/9(44) |
243 | GO:0019899 | enzyme binding | 1/9(44) |
243 | GO:0002175 | protein localization to paranode region of axon | 1/9(44) |
102 | GO:0007155 | cell adhesion | 3/18(88) |
102 | GO:0070062 | extracellular exosome | 2/18(88) |
102 | GO:0007224 | smoothened signaling pathway | 2/18(88) |
229 | GO:0005216 | ion channel activity | 4/13(47) |
589 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity | 4/7(27) |
106 | GO:0003676 | nucleic acid binding | 2/18(84) |
106 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/18(84) |
106 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2/18(84) |
106 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | 1/18(84) |
106 | GO:0001046 | core promoter sequence-specific DNA binding | 3/18(84) |
827 | GO:0000386 | second spliceosomal transesterification activity | 1/2(23) |
105 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/26(85) |
105 | GO:0003677 | DNA binding | 16/26(85) |
39 | GO:0001948 | glycoprotein binding | 2/43(155) |
39 | GO:0005198 | structural molecule activity | 14/43(155) |
1387 | GO:0005524 | ATP binding | 3/4(17) |
1432 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/3(17) |
292 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 4/8(39) |
292 | GO:0003676 | nucleic acid binding | 1/8(39) |
31 | GO:0004252 | serine-type endopeptidase activity | 2/24(171) |
31 | GO:0001964 | startle response | 2/24(171) |
31 | GO:0016020 | membrane | 2/24(171) |
31 | GO:0008344 | adult locomotory behavior | 2/24(171) |
31 | GO:0003682 | chromatin binding | 1/24(171) |
2572 | GO:0010181 | FMN binding | 1/2(10) |
21 | GO:0001221 | transcription cofactor binding | 1/62(240) |
21 | GO:0001046 | core promoter sequence-specific DNA binding | 2/62(240) |
21 | GO:0000166 | nucleotide binding | 1/62(240) |
21 | GO:0001105 | RNA polymerase II transcription coactivator activity | 2/62(240) |
21 | GO:0003676 | nucleic acid binding | 5/62(240) |
21 | GO:0003677 | DNA binding | 6/62(240) |
21 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 3/62(240) |
21 | GO:0003682 | chromatin binding | 3/62(240) |
21 | GO:0005524 | ATP binding | 12/62(240) |
1126 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 2/4(18) |
9398 | GO:0003735 | structural constituent of ribosome | 1/2(5) |
1632 | GO:0006810 | transport | 1/4(16) |
1632 | GO:0008526 | phosphatidylinositol transporter activity | 1/4(16) |
35 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 2/37(166) |
35 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 6/37(166) |
35 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2/37(166) |
35 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | 1/37(166) |
35 | GO:0003677 | DNA binding | 3/37(166) |
1245 | GO:0016491 | oxidoreductase activity | 2/2(17) |
2379 | GO:0004046 | aminoacylase activity | 2/4(12) |
2379 | GO:0016020 | membrane | 1/4(12) |
990 | GO:0048706 | embryonic skeletal system development | 1/5(21) |
2676 | GO:0002053 | positive regulation of mesenchymal cell proliferation | 1/2(10) |
114 | GO:0004620 | phospholipase activity | 8/22(79) |
40 | GO:0003924 | GTPase activity | 9/40(152) |
40 | GO:0004871 | signal transducer activity | 3/40(152) |
40 | GO:0005525 | GTP binding | 19/40(152) |
1004 | GO:0008270 | zinc ion binding | 1/3(20) |
1003 | GO:0003779 | actin binding | 1/4(20) |
1003 | GO:0030018 | Z disc | 1/4(20) |
963 | GO:0003690 | double-stranded DNA binding | 2/5(21) |
963 | GO:0003677 | DNA binding | 1/5(21) |
2162 | GO:0003723 | RNA binding | 3/3(14) |
637 | GO:0004888 | transmembrane signaling receptor activity | 4/9(25) |
637 | GO:0005149 | interleukin-1 receptor binding | 2/9(25) |
637 | GO:0019843 | rRNA binding | 1/9(25) |
1164 | GO:0008270 | zinc ion binding | 1/5(18) |
44 | GO:0004497 | monooxygenase activity | 26/47(148) |
44 | GO:0005506 | iron ion binding | 2/47(148) |
2459 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity | 2/2(11) |
338 | GO:0016491 | oxidoreductase activity | 2/10(35) |
338 | GO:0004362 | glutathione-disulfide reductase activity | 1/10(35) |
338 | GO:0004791 | thioredoxin-disulfide reductase activity | 5/10(35) |
9126 | GO:0005184 | neuropeptide hormone activity | 1/2(5) |
624 | GO:0046983 | protein dimerization activity | 2/6(26) |
624 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/6(26) |
8210 | GO:0055085 | transmembrane transport | 2/2(7) |
570 | GO:0008270 | zinc ion binding | 3/6(27) |
454 | GO:0005198 | structural molecule activity | 5/7(31) |
455 | GO:0004871 | signal transducer activity | 2/5(31) |
2294 | GO:0005159 | insulin-like growth factor receptor binding | 1/4(13) |
2294 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway | 2/4(13) |
60 | GO:0005737 | cytoplasm | 1/27(120) |
60 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/27(120) |
60 | GO:0005200 | structural constituent of cytoskeleton | 1/27(120) |
60 | GO:0005524 | ATP binding | 1/27(120) |
60 | GO:0000166 | nucleotide binding | 9/27(120) |
9639 | GO:0004129 | cytochrome-c oxidase activity | 2/2(4) |
258 | GO:0000166 | nucleotide binding | 3/8(42) |
89 | GO:0000166 | nucleotide binding | 9/18(97) |
2196 | GO:0003682 | chromatin binding | 2/3(13) |
252 | GO:0019992 | diacylglycerol binding | 4/7(42) |
252 | GO:0030742 | GTP-dependent protein binding | 1/7(42) |
2730 | GO:0005102 | receptor binding | 1/2(10) |
175 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2/9(56) |
175 | GO:0003677 | DNA binding | 2/9(56) |
251 | GO:0009922 | fatty acid elongase activity | 3/11(43) |
251 | GO:0001104 | RNA polymerase II transcription cofactor activity | 2/11(43) |
251 | GO:0016740 | transferase activity | 2/11(43) |
9635 | GO:0005783 | endoplasmic reticulum | 2/2(4) |
347 | GO:0000166 | nucleotide binding | 4/7(35) |
255 | GO:0004497 | monooxygenase activity | 3/9(42) |
2051 | GO:0003723 | RNA binding | 2/5(15) |
1423 | GO:0000166 | nucleotide binding | 4/4(17) |
3210 | GO:0016020 | membrane | 1/2(9) |
2054 | GO:0003824 | catalytic activity | 1/2(15) |
8994 | GO:0005737 | cytoplasm | 2/2(6) |
978 | GO:0016407 | acetyltransferase activity | 2/5(21) |
978 | GO:0004596 | peptide alpha-N-acetyltransferase activity | 1/5(21) |
2770 | GO:0008237 | metallopeptidase activity | 2/3(10) |
2 | GO:0000166 | nucleotide binding | 33/155(642) |
2 | GO:0003924 | GTPase activity | 35/155(642) |
2 | GO:0005509 | calcium ion binding | 2/155(642) |
2 | GO:0005525 | GTP binding | 32/155(642) |
186 | GO:0005216 | ion channel activity | 11/13(52) |
1796 | GO:0003677 | DNA binding | 2/2(16) |
184 | GO:0000226 | microtubule cytoskeleton organization | 1/6(55) |
6 | GO:0005200 | structural constituent of cytoskeleton | 1/103(437) |
6 | GO:1990126 | retrograde transport, endosome to plasma membrane | 2/103(437) |
6 | GO:0007165 | signal transduction | 2/103(437) |
6 | GO:0003676 | nucleic acid binding | 2/103(437) |
6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity | 2/103(437) |
6 | GO:0035556 | intracellular signal transduction | 1/103(437) |
6 | GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | 1/103(437) |
6 | GO:0000149 | SNARE binding | 1/103(437) |
6 | GO:0019887 | protein kinase regulator activity | 1/103(437) |
6 | GO:0004672 | protein kinase activity | 2/103(437) |
6 | GO:0008134 | transcription factor binding | 2/103(437) |
6 | GO:0090090 | negative regulation of canonical Wnt signaling pathway | 3/103(437) |
6 | GO:0044212 | transcription regulatory region DNA binding | 1/103(437) |
6 | GO:0005216 | ion channel activity | 2/103(437) |
6 | GO:0017137 | Rab GTPase binding | 1/103(437) |
6 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity | 2/103(437) |
6 | GO:0045893 | positive regulation of transcription, DNA-templated | 2/103(437) |
6 | GO:0007520 | myoblast fusion | 2/103(437) |
6 | GO:0001085 | RNA polymerase II transcription factor binding | 2/103(437) |
6 | GO:0010613 | positive regulation of cardiac muscle hypertrophy | 1/103(437) |
6 | GO:0008093 | cytoskeletal adaptor activity | 1/103(437) |
6 | GO:0016567 | protein ubiquitination | 3/103(437) |
6 | GO:0005634 | nucleus | 2/103(437) |
2110 | GO:0003677 | DNA binding | 2/4(14) |
1217 | GO:0019900 | kinase binding | 2/4(18) |
189 | GO:0004407 | histone deacetylase activity | 1/8(51) |
189 | GO:0001025 | RNA polymerase III transcription factor binding | 1/8(51) |
1037 | GO:0016301 | kinase activity | 3/6(20) |
500 | GO:0004871 | signal transducer activity | 5/7(29) |
4 | GO:0001948 | glycoprotein binding | 1/119(497) |
4 | GO:0004252 | serine-type endopeptidase activity | 50/119(497) |
4 | GO:0004175 | endopeptidase activity | 2/119(497) |
3878 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2/2(9) |
3879 | GO:0004864 | protein phosphatase inhibitor activity | 2/2(9) |
1211 | GO:0008381 | mechanically-gated ion channel activity | 1/4(18) |
9137 | GO:0003714 | transcription corepressor activity | 1/2(5) |
906 | GO:0005509 | calcium ion binding | 3/4(22) |
10407 | GO:0000166 | nucleotide binding | 1/1(2) |
465 | GO:0006355 | regulation of transcription, DNA-templated | 1/10(31) |
465 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/10(31) |
465 | GO:0003677 | DNA binding | 1/10(31) |
9138 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity | 1/2(5) |
9505 | GO:0019899 | enzyme binding | 1/2(4) |
2735 | GO:0051225 | spindle assembly | 1/2(10) |
506 | GO:0010506 | regulation of autophagy | 2/6(29) |
111 | GO:0005201 | extracellular matrix structural constituent | 1/21(82) |
111 | GO:0005615 | extracellular space | 3/21(82) |
111 | GO:0044822 | poly(A) RNA binding | 1/21(82) |
111 | GO:0031012 | extracellular matrix | 2/21(82) |
111 | GO:0002020 | protease binding | 1/21(82) |
111 | GO:0035987 | endodermal cell differentiation | 2/21(82) |
787 | GO:0005216 | ion channel activity | 1/6(24) |
787 | GO:0005516 | calmodulin binding | 2/6(24) |
2186 | GO:0090002 | establishment of protein localization to plasma membrane | 2/3(14) |
2185 | GO:0004812 | aminoacyl-tRNA ligase activity | 2/4(14) |
8 | GO:0003774 | motor activity | 3/108(417) |
8 | GO:0007165 | signal transduction | 1/108(417) |
8 | GO:0000146 | microfilament motor activity | 8/108(417) |
8 | GO:0000166 | nucleotide binding | 38/108(417) |
9623 | GO:0005654 | nucleoplasm | 1/1(4) |
90 | GO:0005198 | structural molecule activity | 18/37(97) |
10011 | GO:0005739 | mitochondrion | 2/2(3) |
3631 | GO:0003677 | DNA binding | 1/2(9) |
95 | GO:0004842 | ubiquitin-protein transferase activity | 1/21(95) |
95 | GO:0008270 | zinc ion binding | 5/21(95) |
161 | GO:0003824 | catalytic activity | 1/10(57) |
161 | GO:0007165 | signal transduction | 1/10(57) |
161 | GO:0042803 | protein homodimerization activity | 2/10(57) |
97 | GO:0003958 | NADPH-hemoprotein reductase activity | 3/19(91) |
97 | GO:0005272 | sodium channel activity | 3/19(91) |
97 | GO:0005261 | cation channel activity | 1/19(91) |
97 | GO:0004517 | nitric-oxide synthase activity | 3/19(91) |
11 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 9/99(347) |
11 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1/99(347) |
11 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 1/99(347) |
11 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 3/99(347) |
11 | GO:0003677 | DNA binding | 30/99(347) |
10 | GO:0005509 | calcium ion binding | 34/114(380) |
8513 | GO:0005096 | GTPase activator activity | 1/2(6) |
12 | GO:0004930 | G-protein coupled receptor activity | 6/93(341) |
12 | GO:0004871 | signal transducer activity | 51/93(341) |
12 | GO:0001626 | nociceptin receptor activity | 2/93(341) |
12 | GO:0001596 | angiotensin type I receptor activity | 2/93(341) |
12 | GO:0003779 | actin binding | 2/93(341) |
12 | GO:0001965 | G-protein alpha-subunit binding | 1/93(341) |
12 | GO:0002020 | protease binding | 2/93(341) |
1021 | GO:0003676 | nucleic acid binding | 2/2(20) |
36 | GO:0005112 | Notch binding | 10/30(160) |
36 | GO:0001047 | core promoter binding | 1/30(160) |
36 | GO:0005509 | calcium ion binding | 5/30(160) |
392 | GO:0003779 | actin binding | 2/9(33) |
18 | GO:0001588 | dopamine neurotransmitter receptor activity, coupled via Gs | 2/66(256) |
18 | GO:0004930 | G-protein coupled receptor activity | 1/66(256) |
18 | GO:0001594 | trace-amine receptor activity | 1/66(256) |
18 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go | 4/66(256) |
18 | GO:0001587 | Gq/11-coupled serotonin receptor activity | 2/66(256) |
18 | GO:0001965 | G-protein alpha-subunit binding | 2/66(256) |
18 | GO:0004871 | signal transducer activity | 28/66(256) |
1282 | GO:0001102 | RNA polymerase II activating transcription factor binding | 2/4(17) |
865 | GO:0005506 | iron ion binding | 2/4(23) |
864 | GO:0007275 | multicellular organism development | 2/4(23) |
864 | GO:0001736 | establishment of planar polarity | 2/4(23) |
1104 | GO:0016740 | transferase activity | 2/4(19) |
1104 | GO:0015020 | glucuronosyltransferase activity | 1/4(19) |
390 | GO:0019900 | kinase binding | 4/9(33) |
390 | GO:0003713 | transcription coactivator activity | 1/9(33) |
2242 | GO:0000062 | fatty-acyl-CoA binding | 2/4(13) |
32 | GO:0002020 | protease binding | 1/58(170) |
32 | GO:0016525 | negative regulation of angiogenesis | 2/58(170) |
32 | GO:0005615 | extracellular space | 19/58(170) |
32 | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling | 1/58(170) |
32 | GO:0004867 | serine-type endopeptidase inhibitor activity | 8/58(170) |
8580 | GO:0003676 | nucleic acid binding | 1/2(6) |
3334 | GO:0005737 | cytoplasm | 2/2(9) |
501 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 2/9(29) |
501 | GO:0003677 | DNA binding | 6/9(29) |
774 | GO:0015909 | long-chain fatty acid transport | 2/4(24) |
10368 | GO:0009116 | nucleoside metabolic process | 1/1(2) |
883 | GO:0030534 | adult behavior | 1/4(23) |
568 | GO:0005246 | calcium channel regulator activity | 1/5(27) |
9342 | GO:0001601 | peptide YY receptor activity | 2/3(5) |
559 | GO:0046983 | protein dimerization activity | 3/7(27) |
559 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 1/7(27) |
559 | GO:0001102 | RNA polymerase II activating transcription factor binding | 1/7(27) |
2866 | GO:0016020 | membrane | 1/2(9) |
8177 | GO:0005737 | cytoplasm | 2/2(7) |
2634 | GO:0008168 | methyltransferase activity | 2/2(10) |
556 | GO:0044822 | poly(A) RNA binding | 1/4(27) |
1169 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 1/4(18) |
1169 | GO:0003713 | transcription coactivator activity | 1/4(18) |
10658 | GO:0004045 | aminoacyl-tRNA hydrolase activity | 1/1(2) |
552 | GO:0001047 | core promoter binding | 1/6(28) |
2439 | GO:0042803 | protein homodimerization activity | 1/2(11) |
118 | GO:0016301 | kinase activity | 8/20(77) |
118 | GO:0046854 | phosphatidylinositol phosphorylation | 1/20(77) |
118 | GO:0000166 | nucleotide binding | 2/20(77) |
1292 | GO:0004842 | ubiquitin-protein transferase activity | 1/4(17) |
9752 | GO:0001664 | G-protein coupled receptor binding | 2/2(3) |
2949 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity | 2/2(9) |
234 | GO:0003677 | DNA binding | 4/11(46) |
237 | GO:0016740 | transferase activity | 2/15(45) |
237 | GO:0004307 | ethanolaminephosphotransferase activity | 1/15(45) |
230 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/10(47) |
230 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 2/10(47) |
230 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2/10(47) |
230 | GO:0001047 | core promoter binding | 1/10(47) |
1891 | GO:0016020 | membrane | 3/3(16) |
9160 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 1/2(5) |
233 | GO:0005178 | integrin binding | 1/10(46) |
233 | GO:0005201 | extracellular matrix structural constituent | 1/10(46) |
3438 | GO:0032947 | protein complex scaffold | 2/2(9) |
1051 | GO:0005267 | potassium channel activity | 2/5(20) |
1051 | GO:0005249 | voltage-gated potassium channel activity | 2/5(20) |
81 | GO:0003779 | actin binding | 1/27(102) |
81 | GO:0005856 | cytoskeleton | 4/27(102) |
81 | GO:0010592 | positive regulation of lamellipodium assembly | 1/27(102) |
81 | GO:0004721 | phosphoprotein phosphatase activity | 2/27(102) |
81 | GO:0008092 | cytoskeletal protein binding | 2/27(102) |
893 | GO:0003824 | catalytic activity | 5/6(22) |
878 | GO:0005615 | extracellular space | 1/7(23) |
878 | GO:0004866 | endopeptidase inhibitor activity | 5/7(23) |
49 | GO:0003777 | microtubule motor activity | 11/30(138) |
951 | GO:0004842 | ubiquitin-protein transferase activity | 2/4(21) |
951 | GO:0008270 | zinc ion binding | 1/4(21) |
1193 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity | 1/3(18) |
875 | GO:0002244 | hematopoietic progenitor cell differentiation | 1/4(23) |
954 | GO:0016020 | membrane | 1/4(21) |
870 | GO:0000166 | nucleotide binding | 3/6(23) |
956 | GO:0050770 | regulation of axonogenesis | 2/5(21) |
1 | GO:0001223 | transcription coactivator binding | 2/267(729) |
1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 3/267(729) |
1 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 1/267(729) |
1 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 6/267(729) |
1 | GO:0003676 | nucleic acid binding | 66/267(729) |
1 | GO:0001046 | core promoter sequence-specific DNA binding | 1/267(729) |
1 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 9/267(729) |
1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | 2/267(729) |
1 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1/267(729) |
321 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity | 4/9(37) |
5 | GO:0000287 | magnesium ion binding | 2/130(478) |
5 | GO:0000166 | nucleotide binding | 70/130(478) |
5 | GO:0004674 | protein serine/threonine kinase activity | 1/130(478) |
5 | GO:0004672 | protein kinase activity | 10/130(478) |
5 | GO:0046872 | metal ion binding | 1/130(478) |
5 | GO:0002039 | p53 binding | 2/130(478) |
1117 | GO:0008053 | mitochondrial fusion | 2/6(19) |
1117 | GO:0042803 | protein homodimerization activity | 2/6(19) |
9 | GO:0007626 | locomotory behavior | 1/100(386) |
9 | GO:0000070 | mitotic sister chromatid segregation | 1/100(386) |
9 | GO:0000902 | cell morphogenesis | 2/100(386) |
9 | GO:0005783 | endoplasmic reticulum | 1/100(386) |
9 | GO:0006355 | regulation of transcription, DNA-templated | 2/100(386) |
9 | GO:0002467 | germinal center formation | 2/100(386) |
9 | GO:0051015 | actin filament binding | 1/100(386) |
9 | GO:0003779 | actin binding | 6/100(386) |
9 | GO:0016567 | protein ubiquitination | 8/100(386) |
9 | GO:2001243 | negative regulation of intrinsic apoptotic signaling pathway | 1/100(386) |
9 | GO:0007010 | cytoskeleton organization | 1/100(386) |
9 | GO:0031397 | negative regulation of protein ubiquitination | 2/100(386) |
9 | GO:2000312 | regulation of kainate selective glutamate receptor activity | 2/100(386) |
9 | GO:0004842 | ubiquitin-protein transferase activity | 4/100(386) |
9 | GO:0006446 | regulation of translational initiation | 3/100(386) |
9 | GO:0042802 | identical protein binding | 3/100(386) |
9 | GO:0005615 | extracellular space | 2/100(386) |
3079 | GO:0004222 | metalloendopeptidase activity | 1/1(9) |
1294 | GO:0008270 | zinc ion binding | 2/4(17) |
201 | GO:0001104 | RNA polymerase II transcription cofactor activity | 1/13(50) |
201 | GO:0005215 | transporter activity | 9/13(50) |
1050 | GO:0015269 | calcium-activated potassium channel activity | 3/4(20) |
203 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/14(49) |
203 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 3/14(49) |
203 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | 1/14(49) |
203 | GO:0006366 | transcription from RNA polymerase II promoter | 1/14(49) |
2629 | GO:0000132 | establishment of mitotic spindle orientation | 1/2(10) |
142 | GO:0000166 | nucleotide binding | 6/13(63) |
10194 | GO:0019079 | viral genome replication | 1/1(2) |
140 | GO:0000150 | recombinase activity | 1/6(64) |
140 | GO:0000166 | nucleotide binding | 2/6(64) |
2401 | GO:0004871 | signal transducer activity | 1/2(12) |
611 | GO:0004842 | ubiquitin-protein transferase activity | 3/5(26) |
2386 | GO:0005185 | neurohypophyseal hormone activity | 3/4(12) |
615 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1/6(26) |
77 | GO:0004675 | transmembrane receptor protein serine/threonine kinase activity | 1/26(103) |
77 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | 1/26(103) |
77 | GO:0000166 | nucleotide binding | 20/26(103) |
8799 | GO:0005739 | mitochondrion | 2/2(6) |
831 | GO:0004668 | protein-arginine deiminase activity | 1/4(23) |
73 | GO:0004222 | metalloendopeptidase activity | 8/26(108) |
5204 | GO:0016020 | membrane | 1/1(8) |
70 | GO:0004871 | signal transducer activity | 15/23(109) |
567 | GO:0005102 | receptor binding | 4/7(27) |
567 | GO:0008083 | growth factor activity | 1/7(27) |
78 | GO:0005216 | ion channel activity | 2/14(103) |
78 | GO:0005245 | voltage-gated calcium channel activity | 1/14(103) |
1041 | GO:0001786 | phosphatidylserine binding | 2/4(20) |
1046 | GO:0005634 | nucleus | 1/6(20) |
1046 | GO:0016020 | membrane | 3/6(20) |
1046 | GO:0005783 | endoplasmic reticulum | 1/6(20) |
262 | GO:0003700 | transcription factor activity, sequence-specific DNA binding | 1/11(42) |
262 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding | 2/11(42) |
262 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 3/11(42) |
262 | GO:0000976 | transcription regulatory region sequence-specific DNA binding | 2/11(42) |
262 | GO:0001158 | enhancer sequence-specific DNA binding | 1/11(42) |
705 | GO:0005085 | guanyl-nucleotide exchange factor activity | 1/6(25) |
2342 | GO:0015187 | glycine transmembrane transporter activity | 2/4(12) |
2234 | GO:0004872 | receptor activity | 1/3(13) |
940 | GO:0004871 | signal transducer activity | 3/11(22) |
46 | GO:0004435 | phosphatidylinositol phospholipase C activity | 14/34(146) |
46 | GO:0001786 | phosphatidylserine binding | 2/34(146) |
9032 | GO:0008565 | protein transporter activity | 1/2(6) |
353 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding | 2/8(34) |
353 | GO:0003677 | DNA binding | 1/8(34) |
2007 | GO:0016020 | membrane | 1/2(15) |
8647 | GO:0005216 | ion channel activity | 2/2(6) |
516 | GO:0000287 | magnesium ion binding | 2/5(29) |
516 | GO:0004672 | protein kinase activity | 1/5(29) |
7466 | GO:0005604 | basement membrane | 2/2(8) |
187 | GO:0005201 | extracellular matrix structural constituent | 2/12(52) |
169 | GO:0009897 | external side of plasma membrane | 1/18(57) |
169 | GO:0016020 | membrane | 5/18(57) |
169 | GO:0043274 | phospholipase binding | 2/18(57) |
169 | GO:0005518 | collagen binding | 1/18(57) |