BOP - Node PARADISAEA

Node summary

Genes	16883
Ancestral node	BOP5

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CAFE summary

Expansions	248 (40 rapid)
Contractions	209 (3 rapid)
Extinctions	85

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Family list

GO Terms

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Family ID	Gene Count	Change	Rapid (*)?	Exctinction (--)?

9256	0	-1		--
2683	3	+2	*
90	11	+1
95	11	-1
94	20	+2
97	11	-1
96	13	+1
1179	3	+1
876	3	-1
870	4	+1
2745	2	+1
2039	1	-1
390	5	+1
399	3	-1
2302	1	-1
175	10	+2	*
6218	2	+1
9752	0	-1		--
9758	0	-1		--
699	5	+1
258	5	-1
251	6	+1
9505	0	-1		--
2514	2	+1
2517	2	+1
10182	0	-1		--
10189	0	-1		--
1154	2	-1
2186	3	+1
159	4	-1
2723	2	+1	*
2722	2	+1
9777	0	-1		--
9770	0	-1		--
814	4	+1
3028	2	+1
239	5	-1
236	7	+1
237	4	-1
231	5	-1
233	4	-1
9566	0	-1		--
9567	0	-1		--
932	2	-1
936	4	+1
2145	3	+1
2415	0	-1		--
2414	1	-1
1139	3	+1
1130	3	+1
8503	2	+1	*
2885	2	+1
2	86	+1
1926	1	-1
2703	2	+1
9173	0	-1		--
9170	0	-1		--
838	2	-1
9002	0	-1		--
9457	0	-1		--
218	7	+1
219	8	+1
2552	4	+2	*
2558	0	-2	*	--
919	2	-1
915	4	+1
8073	0	-1		--
1112	3	+1
191	8	+2
2769	2	+1
2768	2	+1
9151	0	-1		--
9150	0	-1		--
2760	2	+1
2765	2	+1
1183	1	-1
3451	2	+1
6	61	+2
492	5	+1
493	6	+2
2571	2	+1
975	3	+1
973	2	-1
8924	0	-1		--
313	7	+2
312	7	+2	*
315	6	+1
2293	3	+1
8693	2	+1
9138	0	-1		--
3439	2	+1
878	2	-1
873	5	+2	*
5204	2	+1	*
1094	3	+1
1095	4	+1
1091	3	+1
8355	0	-1		--
956	2	-1
4969	2	+1
590	4	+1
2826	2	+1
1540	3	+1
9447	2	+1	*
9441	2	+1	*
9530	0	-1		--
833	5	+2	*
9573	0	-1		--
2464	1	-1
2467	2	+1	*
2468	1	-1
1026	2	-1
1020	4	+1
9303	0	-1		--
9578	0	-1		--
570	3	-1
8580	0	-1		--
8270	0	-1		--
356	5	+1
353	4	-1
2258	1	-1
2253	2	+1	*
9462	0	-1		--
9808	0	-1		--
4028	0	-1		--
297	4	-1
290	2	-3	*
2444	2	+1
9322	0	-1		--
559	3	-1
555	2	-1
550	4	+1
1193	2	-1
7696	2	+1
373	5	+1
2277	1	-1
2054	3	+1
2059	1	-1
1387	3	+1
8107	2	+1	*
2421	2	+1
2423	2	+1
2426	1	-1
2427	1	-1
9342	0	-1		--
2847	2	+1	*
3328	2	+1
3815	2	+1
2219	3	+1
5288	2	+1
9022	0	-1		--
2981	2	+1
1016	2	-1
1017	4	+1
439	3	-1
9497	0	-1		--
1430	3	+1
3798	2	+1
2409	1	-1
3245	2	+1
1482	2	-1
1992	1	-1
614	2	-1
615	3	-1
514	5	+1
1226	4	+1
3870	2	+1
3877	2	+1
8476	2	+1	*
2238	1	-1
3492	2	+1
3	64	-1
3330	2	+1	*
1032	2	-1
1033	2	-1
1037	3	+1
2394	1	-1
2398	2	+1
2179	1	-1
1429	3	+1
8275	0	-1		--
462	3	-1
8414	0	-1		--
5912	2	+1	*
2617	2	+1
2616	2	+1
1050	2	-1
2134	1	-1
2135	1	-1
2379	2	+1
2373	1	-1
2116	1	-1
9239	0	-1		--
8251	2	+1
665	4	+1
664	4	+1
8514	0	-1		--
2634	2	+1
9227	0	-1		--
9044	0	-1		--
760	2	-1
5760	2	+1
2351	1	-1
2354	2	+1
1790	2	+1
1796	3	+1
9469	0	-1		--
9843	0	-1		--
3892	3	+1
9200	0	-1		--
2655	2	+1
705	2	-1
1987	3	+1
569	4	+1
121	11	+1
122	11	+2
128	9	-1
8216	0	-1		--
7659	0	-1		--
261	6	+1
260	4	-1
264	6	+1
268	6	+1
6016	2	+1
9263	0	-1		--
981	2	-1
1389	3	+1
2676	2	+1
1209	3	+1
726	4	+1
2315	0	-1		--
105	9	-1
1282	3	+1
688	3	-1
683	3	-1
8505	2	+1	*
240	7	+1
243	7	+1
9531	0	-1		--
1366	3	+1
3527	2	+1
2694	2	+1
2690	2	+1	*
766	3	-1
381	6	+1
383	5	+1
388	6	+2
2196	1	-1
165	5	-1
160	8	+1
162	10	+2	*
163	9	+2
9760	0	-1		--
9287	0	-1		--
8701	0	-1		--
222	6	-1
2509	2	+1
2508	1	-1
2500	3	+1
9511	0	-1		--
10194	0	-1		--
10199	0	-1		--
5188	0	-1		--
1122	4	+2
1126	2	-1
144	7	+1
140	13	+2
3343	2	+1
2717	2	+1
9160	0	-1		--
6248	2	+1	*
823	2	-1
3017	2	+1
11	45	+2
13	43	-1
12	44	+2
15	37	-1
14	41	+2
16	34	+1
19	33	+1
18	33	+1
831	4	+1
836	4	+3	*
3657	2	+1
2521	1	-1
2528	2	+1
9575	0	-1		--
1104	2	-1
1896	3	+1
4	67	+1
2775	2	+1
841	5	+2	*
840	2	-1
3079	1	-1
487	5	+1
3677	2	+1
2545	2	+1
4427	2	+1
26	4	+1
27	24	+1
21	31	+1
22	33	+2
28	26	+1
1066	4	+1
2286	1	-1
9126	0	-1		--
9128	0	-1		--
184	13	+5	*
867	5	+2	*
2026	1	-1
2020	3	+1
2759	2	+1	*
10152	0	-1		--
8	50	-1
2568	1	-1
2560	0	-1		--
967	2	-1
963	2	-1
1245	3	+1
1414	3	+1
300	3	-2	*
2773	2	+1
9145	0	-1		--
2001	3	+1
8159	2	+1	*
9546	0	-1		--
1086	3	+1
1083	2	-1
39	15	-2
7701	0	-1		--
33	20	-1
31	29	+3	*
30	30	+6	*
37	19	-1
35	25	+1
584	2	-1
588	4	-1
2833	2	+1
321	6	+1
6132	2	+1	*
9474	0	-1		--
9475	0	-1		--
2246	1	-1
2240	1	-1
2242	1	-1
2798	2	+1
8104	0	-1		--
464	5	+1
467	5	+1
288	6	+1
2477	2	+1
8950	0	-1		--
2819	2	+1
3378	2	+1
48	19	+1
49	14	-1
44	18	+1
41	22	+1
10151	0	-1		--
2876	2	+1
543	5	+1
541	3	-1
8442	0	-1		--
366	5	+1
363	6	+2
361	4	-1
9486	0	-1		--
8140	0	-1		--
55	18	+1
54	16	-1
57	18	+1
2997	2	+1
854	4	+1
1422	3	+1
10173	0	-1		--
10176	0	-1		--
1949	1	-1
528	3	-1
529	3	-1
1232	1	-1
1964	1	-1
9130	0	-1		--
9137	0	-1		--
3304	2	+1
2663	2	+1
2660	3	+1
1825	3	+1
2412	2	+1
61	16	+1
62	16	+1
63	17	+1
67	15	-1
68	15	+1
69	12	-1
508	6	+1
503	6	+2	*
501	5	+2
9816	0	-1		--
4152	0	-1		--
2605	2	+1
2608	2	+1
1029	2	-1
5	57	-1
2382	3	+2	*
2386	1	-1
2389	1	-1
611	3	-1
1073	4	+2
2595	2	+1
2596	2	+1
1070	3	+1
2622	2	+1
2625	1	-1
10016	2	+1	*
774	4	+1
75	13	-1
70	16	+1
78	16	+1
1048	2	-1
865	4	+1
2757	2	+1
2750	2	+1
2367	1	-1
1787	3	+1
673	4	+1
7606	2	+1	*
2492	1	-1
9269	0	-1		--
3559	2	+1
2344	1	-1
2343	1	-1
2122	1	-1
132	11	+2
130	12	+3	*
135	9	+1
1	75	-2
88	13	+1
83	23	+3	*
80	13	+1
86	12	+1
9192	0	-1		--
9195	0	-1		--
3886	2	+1	*
991	4	+1
990	4	+1
992	5	+3	*
9279	0	-1		--
9099	2	+1	*
731	2	-1
2405	1	-1
2151	2	+1
8562	0	-1		--
2328	1	-1
2499	1	-1
119	8	-1
118	11	+2
8556	0	-1		--

Family ID	GO ID	GO term	# genes w/ GO ID

5	GO:0000287	magnesium ion binding	2/130(478)
5	GO:0000166	nucleotide binding	70/130(478)
5	GO:0004674	protein serine/threonine kinase activity	1/130(478)
5	GO:0004672	protein kinase activity	10/130(478)
5	GO:0046872	metal ion binding	1/130(478)
5	GO:0002039	p53 binding	2/130(478)
8251	GO:0016020	membrane	1/1(7)
2717	GO:0005813	centrosome	1/2(10)
665	GO:0005096	GTPase activator activity	2/6(25)
665	GO:0001786	phosphatidylserine binding	1/6(25)
664	GO:0004842	ubiquitin-protein transferase activity	3/6(25)
766	GO:0005049	nuclear export signal receptor activity	1/5(24)
218	GO:0016020	membrane	3/13(48)
218	GO:0004745	retinol dehydrogenase activity	2/13(48)
219	GO:0000166	nucleotide binding	7/10(48)
132	GO:0004721	phosphoprotein phosphatase activity	8/14(68)
130	GO:0001849	complement component C1q binding	1/14(69)
130	GO:0005178	integrin binding	1/14(69)
130	GO:0005201	extracellular matrix structural constituent	2/14(69)
130	GO:0005509	calcium ion binding	1/14(69)
2499	GO:0005154	epidermal growth factor receptor binding	1/2(11)
135	GO:0000155	phosphorelay sensor kinase activity	3/15(65)
135	GO:0005216	ion channel activity	1/15(65)
165	GO:0003677	DNA binding	20/24(57)
41	GO:0000166	nucleotide binding	2/52(151)
41	GO:0004672	protein kinase activity	6/52(151)
9160	GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/2(5)
4028	GO:0008289	lipid binding	1/3(8)
493	GO:0002009	morphogenesis of an epithelium	2/6(29)
493	GO:0005509	calcium ion binding	1/6(29)
493	GO:0007154	cell communication	1/6(29)
26	GO:0005200	structural constituent of cytoskeleton	54/166(216)
27	GO:0000166	nucleotide binding	15/49(188)
27	GO:0000287	magnesium ion binding	3/49(188)
27	GO:0002039	p53 binding	1/49(188)
27	GO:0004674	protein serine/threonine kinase activity	1/49(188)
27	GO:0004672	protein kinase activity	5/49(188)
21	GO:0001221	transcription cofactor binding	1/62(240)
21	GO:0001046	core promoter sequence-specific DNA binding	2/62(240)
21	GO:0000166	nucleotide binding	1/62(240)
21	GO:0001105	RNA polymerase II transcription coactivator activity	2/62(240)
21	GO:0003676	nucleic acid binding	5/62(240)
21	GO:0003677	DNA binding	6/62(240)
21	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/62(240)
21	GO:0003682	chromatin binding	3/62(240)
21	GO:0005524	ATP binding	12/62(240)
1540	GO:0005319	lipid transporter activity	2/5(16)
160	GO:0000166	nucleotide binding	9/14(57)
699	GO:0000166	nucleotide binding	2/4(25)
28	GO:0048675	axon extension	2/39(187)
28	GO:0002292	T cell differentiation involved in immune response	1/39(187)
28	GO:0070062	extracellular exosome	1/39(187)
28	GO:0016020	membrane	4/39(187)
28	GO:0004888	transmembrane signaling receptor activity	2/39(187)
28	GO:0004872	receptor activity	1/39(187)
28	GO:0005886	plasma membrane	2/39(187)
28	GO:0001843	neural tube closure	1/39(187)
28	GO:0030215	semaphorin receptor binding	6/39(187)
1073	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/4(19)
1070	GO:0000166	nucleotide binding	4/8(19)
288	GO:0007155	cell adhesion	2/7(40)
288	GO:0019903	protein phosphatase binding	1/7(40)
288	GO:0005518	collagen binding	2/7(40)
321	GO:0017112	Rab guanyl-nucleotide exchange factor activity	4/9(37)
162	GO:0005216	ion channel activity	1/9(57)
162	GO:0006816	calcium ion transport	1/9(57)
8	GO:0003774	motor activity	3/108(417)
8	GO:0007165	signal transduction	1/108(417)
8	GO:0000146	microfilament motor activity	8/108(417)
8	GO:0000166	nucleotide binding	38/108(417)
2246	GO:0005179	hormone activity	1/3(13)
9022	GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/2(6)
814	GO:0043515	kinetochore binding	1/5(23)
814	GO:0002162	dystroglycan binding	1/5(23)
936	GO:0001047	core promoter binding	1/5(22)
936	GO:0003677	DNA binding	1/5(22)
2242	GO:0000062	fatty-acyl-CoA binding	2/4(13)
1094	GO:0005509	calcium ion binding	2/4(19)
1095	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/4(19)
1091	GO:0003677	DNA binding	2/5(19)
1154	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/3(18)
1790	GO:0016407	acetyltransferase activity	7/8(16)
2468	GO:0003676	nucleic acid binding	1/2(11)
1796	GO:0003677	DNA binding	2/2(16)
2703	GO:0044822	poly(A) RNA binding	1/2(10)
673	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/6(25)
121	GO:0002091	negative regulation of receptor internalization	3/17(74)
121	GO:0016020	membrane	1/17(74)
121	GO:0060348	bone development	2/17(74)
121	GO:0051965	positive regulation of synapse assembly	1/17(74)
121	GO:0005518	collagen binding	1/17(74)
121	GO:0001530	lipopolysaccharide binding	1/17(74)
121	GO:0001968	fibronectin binding	1/17(74)
122	GO:0005737	cytoplasm	2/19(74)
122	GO:0005634	nucleus	1/19(74)
122	GO:0001965	G-protein alpha-subunit binding	3/19(74)
122	GO:0005096	GTPase activator activity	3/19(74)
1992	GO:0003824	catalytic activity	1/3(15)
2760	GO:0005509	calcium ion binding	1/2(10)
264	GO:0004871	signal transducer activity	10/12(42)
128	GO:0005543	phospholipid binding	1/12(70)
128	GO:0016021	integral component of membrane	1/12(70)
128	GO:0016020	membrane	2/12(70)
268	GO:0008378	galactosyltransferase activity	7/10(41)
1949	GO:0016020	membrane	1/5(15)
1949	GO:0016746	transferase activity, transferring acyl groups	3/5(15)
10194	GO:0019079	viral genome replication	1/1(2)
6016	GO:0005506	iron ion binding	2/2(8)
55	GO:0001948	glycoprotein binding	1/29(130)
55	GO:0001764	neuron migration	1/29(130)
55	GO:0002020	protease binding	2/29(130)
55	GO:0007155	cell adhesion	4/29(130)
55	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	1/29(130)
55	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/29(130)
55	GO:0005112	Notch binding	2/29(130)
55	GO:0030506	ankyrin binding	2/29(130)
54	GO:0000166	nucleotide binding	20/33(131)
57	GO:0000166	nucleotide binding	21/30(129)
963	GO:0003690	double-stranded DNA binding	2/5(21)
963	GO:0003677	DNA binding	1/5(21)
8701	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/2(6)
967	GO:0003993	acid phosphatase activity	3/6(21)
1066	GO:0003735	structural constituent of ribosome	1/3(19)
1066	GO:0006396	RNA processing	1/3(19)
1825	GO:0004867	serine-type endopeptidase inhibitor activity	2/4(16)
2145	GO:0004672	protein kinase activity	1/3(14)
2412	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	2/2(11)
2415	GO:0016020	membrane	4/5(11)
2414	GO:0003677	DNA binding	1/2(11)
2258	GO:0003735	structural constituent of ribosome	3/4(13)
297	GO:0005096	GTPase activator activity	3/8(39)
373	GO:0003950	NAD+ ADP-ribosyltransferase activity	3/8(33)
1387	GO:0005524	ATP binding	3/4(17)
2253	GO:0004842	ubiquitin-protein transferase activity	1/2(13)
5188	GO:0044822	poly(A) RNA binding	1/3(8)
290	GO:0030234	enzyme regulator activity	2/9(39)
290	GO:0003723	RNA binding	1/9(39)
9263	GO:0000045	autophagosome assembly	2/2(5)
590	GO:0008270	zinc ion binding	4/7(27)
2492	GO:0003824	catalytic activity	1/2(11)
1083	GO:0003824	catalytic activity	4/4(19)
313	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5/8(37)
312	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity	2/10(37)
981	GO:0008013	beta-catenin binding	2/4(21)
191	GO:0005178	integrin binding	1/14(51)
191	GO:0005201	extracellular matrix structural constituent	5/14(51)
1139	GO:0000989	transcription factor activity, transcription factor binding	1/4(18)
315	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/7(37)
315	GO:0003677	DNA binding	4/7(37)
88	GO:0000166	nucleotide binding	13/25(97)
390	GO:0019900	kinase binding	4/9(33)
390	GO:0003713	transcription coactivator activity	1/9(33)
8442	GO:0008121	ubiquinol-cytochrome-c reductase activity	2/3(7)
69	GO:0003779	actin binding	5/25(109)
69	GO:0003725	double-stranded RNA binding	1/25(109)
69	GO:0005509	calcium ion binding	3/25(109)
83	GO:0016020	membrane	3/5(101)
399	GO:0006810	transport	3/10(33)
399	GO:0015218	pyrimidine nucleotide transmembrane transporter activity	3/10(33)
399	GO:0005521	lamin binding	1/10(33)
2997	GO:0003723	RNA binding	1/3(9)
86	GO:0003824	catalytic activity	2/27(97)
86	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	13/27(97)
3677	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/2(9)
831	GO:0004668	protein-arginine deiminase activity	1/4(23)
836	GO:0017080	sodium channel regulator activity	2/9(23)
836	GO:0030198	extracellular matrix organization	1/9(23)
2500	GO:0003677	DNA binding	1/1(11)
3028	GO:0004784	superoxide dismutase activity	2/2(9)
9475	GO:0008121	ubiquinol-cytochrome-c reductase activity	3/3(4)
838	GO:0006810	transport	1/6(23)
838	GO:0001786	phosphatidylserine binding	2/6(23)
2302	GO:0006904	vesicle docking involved in exocytosis	1/4(13)
2394	GO:0004550	nucleoside diphosphate kinase activity	2/2(12)
35	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	2/37(166)
35	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	6/37(166)
35	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/37(166)
35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	1/37(166)
35	GO:0003677	DNA binding	3/37(166)
3	GO:0000287	magnesium ion binding	1/139(535)
3	GO:0000166	nucleotide binding	72/139(535)
3	GO:0003779	actin binding	2/139(535)
3	GO:0004713	protein tyrosine kinase activity	1/139(535)
3	GO:0004672	protein kinase activity	11/139(535)
3	GO:0005524	ATP binding	1/139(535)
611	GO:0004842	ubiquitin-protein transferase activity	3/5(26)
919	GO:0000287	magnesium ion binding	4/5(22)
865	GO:0005506	iron ion binding	2/4(23)
2386	GO:0005185	neurohypophyseal hormone activity	3/4(12)
915	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/5(22)
2179	GO:0016192	vesicle-mediated transport	1/3(14)
2179	GO:0004871	signal transducer activity	1/3(14)
528	GO:0005044	scavenger receptor activity	1/5(28)
528	GO:0003682	chromatin binding	1/5(28)
363	GO:0005096	GTPase activator activity	6/9(34)
1389	GO:0032051	clathrin light chain binding	4/4(17)
2286	GO:0008134	transcription factor binding	2/3(13)
2769	GO:0006810	transport	1/2(10)
2768	GO:0006915	apoptotic process	1/3(10)
9150	GO:0016020	membrane	2/2(5)
1232	GO:0009897	external side of plasma membrane	1/4(18)
1232	GO:0016020	membrane	1/4(18)
300	GO:0008092	cytoskeletal protein binding	1/7(38)
1130	GO:0016020	membrane	2/4(18)
2608	GO:0003824	catalytic activity	2/2(10)
2765	GO:0000166	nucleotide binding	1/2(10)
381	GO:0000166	nucleotide binding	2/5(33)
383	GO:0003677	DNA binding	9/11(33)
9002	GO:0016020	membrane	1/2(6)
243	GO:0005509	calcium ion binding	1/9(44)
243	GO:0019899	enzyme binding	1/9(44)
243	GO:0002175	protein localization to paranode region of axon	1/9(44)
388	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/6(33)
2833	GO:0016788	hydrolase activity, acting on ester bonds	2/2(9)
8355	GO:0002020	protease binding	2/2(7)
105	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/26(85)
105	GO:0003677	DNA binding	16/26(85)
39	GO:0001948	glycoprotein binding	2/43(155)
39	GO:0005198	structural molecule activity	14/43(155)
2351	GO:0048407	platelet-derived growth factor binding	1/2(12)
22	GO:0005216	ion channel activity	31/52(233)
1430	GO:0005509	calcium ion binding	2/4(17)
840	GO:0000166	nucleotide binding	5/6(23)
33	GO:0000166	nucleotide binding	26/44(168)
1414	GO:0032403	protein complex binding	1/5(17)
31	GO:0004252	serine-type endopeptidase activity	2/24(171)
31	GO:0001964	startle response	2/24(171)
31	GO:0016020	membrane	2/24(171)
31	GO:0008344	adult locomotory behavior	2/24(171)
31	GO:0003682	chromatin binding	1/24(171)
30	GO:0017147	Wnt-protein binding	1/37(182)
30	GO:0001540	beta-amyloid binding	1/37(182)
30	GO:0005041	low-density lipoprotein receptor activity	2/37(182)
30	GO:0005509	calcium ion binding	6/37(182)
30	GO:0001948	glycoprotein binding	1/37(182)
37	GO:0003700	transcription factor activity, sequence-specific DNA binding	2/39(156)
37	GO:0005102	receptor binding	22/39(156)
37	GO:0003714	transcription corepressor activity	2/39(156)
37	GO:0005096	GTPase activator activity	1/39(156)
3017	GO:0000166	nucleotide binding	1/2(9)
1126	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2/4(18)
2571	GO:0005540	hyaluronic acid binding	1/3(10)
1429	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	2/4(17)
1245	GO:0016491	oxidoreductase activity	2/2(17)
2398	GO:0003676	nucleic acid binding	4/4(12)
439	GO:0000166	nucleotide binding	4/8(32)
514	GO:0019901	protein kinase binding	2/6(29)
2373	GO:0016020	membrane	2/2(12)
2775	GO:0004064	arylesterase activity	1/3(10)
2595	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process	1/2(10)
44	GO:0004497	monooxygenase activity	26/47(148)
44	GO:0005506	iron ion binding	2/47(148)
9126	GO:0005184	neuropeptide hormone activity	1/2(5)
1086	GO:0016020	membrane	1/4(19)
2293	GO:0005634	nucleus	2/2(13)
1422	GO:0006887	exocytosis	2/4(17)
570	GO:0008270	zinc ion binding	3/6(27)
62	GO:0003779	actin binding	4/29(119)
62	GO:0005509	calcium ion binding	11/29(119)
61	GO:0008284	positive regulation of cell proliferation	1/24(119)
61	GO:0005102	receptor binding	4/24(119)
61	GO:0000904	cell morphogenesis involved in differentiation	1/24(119)
61	GO:0001764	neuron migration	1/24(119)
61	GO:0005201	extracellular matrix structural constituent	1/24(119)
258	GO:0000166	nucleotide binding	3/8(42)
63	GO:0001641	group II metabotropic glutamate receptor activity	4/24(116)
63	GO:0004871	signal transducer activity	8/24(116)
3559	GO:0006810	transport	2/2(9)
2196	GO:0003682	chromatin binding	2/3(13)
67	GO:0005216	ion channel activity	7/22(112)
68	GO:0004089	carbonate dehydratase activity	13/26(110)
68	GO:0004064	arylesterase activity	2/26(110)
1209	GO:0016231	beta-N-acetylglucosaminidase activity	1/5(18)
175	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/9(56)
175	GO:0003677	DNA binding	2/9(56)
251	GO:0009922	fatty acid elongase activity	3/11(43)
251	GO:0001104	RNA polymerase II transcription cofactor activity	2/11(43)
251	GO:0016740	transferase activity	2/11(43)
823	GO:0004869	cysteine-type endopeptidase inhibitor activity	1/7(23)
823	GO:0005509	calcium ion binding	4/7(23)
541	GO:0009966	regulation of signal transduction	1/7(28)
541	GO:0005634	nucleus	1/7(28)
975	GO:0000166	nucleotide binding	4/7(21)
3451	GO:0016846	carbon-sulfur lyase activity	1/2(9)
973	GO:0004622	lysophospholipase activity	1/6(21)
2054	GO:0003824	catalytic activity	1/2(15)
543	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/5(28)
2059	GO:0003676	nucleic acid binding	2/4(15)
2059	GO:0004672	protein kinase activity	1/4(15)
240	GO:0000166	nucleotide binding	5/9(44)
731	GO:0008270	zinc ion binding	1/8(24)
159	GO:0000166	nucleotide binding	1/9(58)
2	GO:0000166	nucleotide binding	33/155(642)
2	GO:0003924	GTPase activity	35/155(642)
2	GO:0005509	calcium ion binding	2/155(642)
2	GO:0005525	GTP binding	32/155(642)
184	GO:0000226	microtubule cytoskeleton organization	1/6(55)
6	GO:0005200	structural constituent of cytoskeleton	1/103(437)
6	GO:1990126	retrograde transport, endosome to plasma membrane	2/103(437)
6	GO:0007165	signal transduction	2/103(437)
6	GO:0003676	nucleic acid binding	2/103(437)
6	GO:0003950	NAD+ ADP-ribosyltransferase activity	2/103(437)
6	GO:0035556	intracellular signal transduction	1/103(437)
6	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1/103(437)
6	GO:0000149	SNARE binding	1/103(437)
6	GO:0019887	protein kinase regulator activity	1/103(437)
6	GO:0004672	protein kinase activity	2/103(437)
6	GO:0008134	transcription factor binding	2/103(437)
6	GO:0090090	negative regulation of canonical Wnt signaling pathway	3/103(437)
6	GO:0044212	transcription regulatory region DNA binding	1/103(437)
6	GO:0005216	ion channel activity	2/103(437)
6	GO:0017137	Rab GTPase binding	1/103(437)
6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/103(437)
6	GO:0045893	positive regulation of transcription, DNA-templated	2/103(437)
6	GO:0007520	myoblast fusion	2/103(437)
6	GO:0001085	RNA polymerase II transcription factor binding	2/103(437)
6	GO:0010613	positive regulation of cardiac muscle hypertrophy	1/103(437)
6	GO:0008093	cytoskeletal adaptor activity	1/103(437)
6	GO:0016567	protein ubiquitination	3/103(437)
6	GO:0005634	nucleus	2/103(437)
1032	GO:0046872	metal ion binding	3/5(20)
1032	GO:0005545	1-phosphatidylinositol binding	1/5(20)
1033	GO:0003677	DNA binding	2/4(20)
501	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/9(29)
501	GO:0003677	DNA binding	6/9(29)
9546	GO:0016787	hydrolase activity	1/2(4)
9546	GO:0008768	UDP-sugar diphosphatase activity	1/2(4)
1037	GO:0016301	kinase activity	3/6(20)
4	GO:0001948	glycoprotein binding	1/119(497)
4	GO:0004252	serine-type endopeptidase activity	50/119(497)
4	GO:0004175	endopeptidase activity	2/119(497)
569	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/6(27)
2773	GO:0004896	cytokine receptor activity	1/2(10)
9137	GO:0003714	transcription corepressor activity	1/2(5)
508	GO:0019208	phosphatase regulator activity	1/5(29)
508	GO:0017112	Rab guanyl-nucleotide exchange factor activity	2/5(29)
3870	GO:0042803	protein homodimerization activity	1/2(9)
2421	GO:0000166	nucleotide binding	2/3(11)
467	GO:0044822	poly(A) RNA binding	1/7(31)
467	GO:0016020	membrane	3/7(31)
9138	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	1/2(5)
2819	GO:0008506	sucrose:proton symporter activity	2/2(9)
2426	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	1/2(11)
9505	GO:0019899	enzyme binding	1/2(4)
3892	GO:0003677	DNA binding	1/2(9)
163	GO:0004177	aminopeptidase activity	3/12(57)
163	GO:0008237	metallopeptidase activity	3/12(57)
163	GO:0006508	proteolysis	1/12(57)
8562	GO:0005164	tumor necrosis factor receptor binding	2/2(6)
2186	GO:0090002	establishment of protein localization to plasma membrane	2/3(14)
118	GO:0016301	kinase activity	8/20(77)
118	GO:0046854	phosphatidylinositol phosphorylation	1/20(77)
118	GO:0000166	nucleotide binding	2/20(77)
90	GO:0005198	structural molecule activity	18/37(97)
95	GO:0004842	ubiquitin-protein transferase activity	1/21(95)
95	GO:0008270	zinc ion binding	5/21(95)
222	GO:0005509	calcium ion binding	3/8(48)
97	GO:0003958	NADPH-hemoprotein reductase activity	3/19(91)
97	GO:0005272	sodium channel activity	3/19(91)
97	GO:0005261	cation channel activity	1/19(91)
97	GO:0004517	nitric-oxide synthase activity	3/19(91)
96	GO:0004725	protein tyrosine phosphatase activity	3/21(93)
96	GO:0004722	protein serine/threonine phosphatase activity	1/21(93)
96	GO:0030234	enzyme regulator activity	1/21(93)
96	GO:0004438	phosphatidylinositol-3-phosphatase activity	6/21(93)
11	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9/99(347)
11	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/99(347)
11	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/99(347)
11	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	3/99(347)
11	GO:0003677	DNA binding	30/99(347)
366	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	1/8(34)
366	GO:0003676	nucleic acid binding	3/8(34)
13	GO:0004984	olfactory receptor activity	3/94(336)
13	GO:0004871	signal transducer activity	31/94(336)
13	GO:0003707	steroid hormone receptor activity	1/94(336)
1026	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	4/4(20)
15	GO:0004725	protein tyrosine phosphatase activity	7/74(303)
15	GO:0008134	transcription factor binding	1/74(303)
15	GO:0004721	phosphoprotein phosphatase activity	27/74(303)
15	GO:0001784	phosphotyrosine binding	4/74(303)
15	GO:0003712	transcription cofactor activity	1/74(303)
14	GO:0003777	microtubule motor activity	1/81(313)
14	GO:0000166	nucleotide binding	38/81(313)
3304	GO:0003676	nucleic acid binding	2/2(9)
16	GO:0003676	nucleic acid binding	14/69(264)
16	GO:0000166	nucleotide binding	25/69(264)
19	GO:0004890	GABA-A receptor activity	24/58(244)
19	GO:0005230	extracellular ligand-gated ion channel activity	10/58(244)
19	GO:0006811	ion transport	1/58(244)
18	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	2/66(256)
18	GO:0004930	G-protein coupled receptor activity	1/66(256)
18	GO:0001594	trace-amine receptor activity	1/66(256)
18	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	4/66(256)
18	GO:0001587	Gq/11-coupled serotonin receptor activity	2/66(256)
18	GO:0001965	G-protein alpha-subunit binding	2/66(256)
18	GO:0004871	signal transducer activity	28/66(256)
2219	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/2(13)
1029	GO:0001948	glycoprotein binding	1/5(20)
1029	GO:0005113	patched binding	2/5(20)
8950	GO:0050995	negative regulation of lipid catabolic process	1/1(6)
867	GO:0002060	purine nucleobase binding	2/4(23)
867	GO:0004645	phosphorylase activity	2/4(23)
503	GO:0003677	DNA binding	2/6(29)
841	GO:0007155	cell adhesion	1/3(23)
1104	GO:0016740	transferase activity	2/4(19)
1104	GO:0015020	glucuronosyltransferase activity	1/4(19)
2020	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/3(15)
2020	GO:0003677	DNA binding	1/3(15)
2514	GO:0043015	gamma-tubulin binding	1/3(11)
8580	GO:0003676	nucleic acid binding	1/2(6)
2517	GO:0003824	catalytic activity	2/4(11)
464	GO:0004656	procollagen-proline 4-dioxygenase activity	4/7(31)
239	GO:0003677	DNA binding	7/9(44)
2405	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2(11)
9342	GO:0001601	peptide YY receptor activity	2/3(5)
1048	GO:0019208	phosphatase regulator activity	2/5(20)
1048	GO:0004857	enzyme inhibitor activity	2/5(20)
559	GO:0046983	protein dimerization activity	3/7(27)
559	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/7(27)
559	GO:0001102	RNA polymerase II activating transcription factor binding	1/7(27)
8104	GO:0004484	mRNA guanylyltransferase activity	2/2(7)
555	GO:0006457	protein folding	2/7(27)
555	GO:0005509	calcium ion binding	3/7(27)
2634	GO:0008168	methyltransferase activity	2/2(10)
8073	GO:0006810	transport	1/2(7)
550	GO:0016307	phosphatidylinositol phosphate kinase activity	2/5(28)
2757	GO:0007052	mitotic spindle organization	1/3(10)
9752	GO:0001664	G-protein coupled receptor binding	2/2(3)
584	GO:0004415	hyalurononglucosaminidase activity	2/7(27)
584	GO:0098641	cadherin binding involved in cell-cell adhesion	2/7(27)
236	GO:0008378	galactosyltransferase activity	6/10(45)
237	GO:0016740	transferase activity	2/15(45)
237	GO:0004307	ethanolaminephosphotransferase activity	1/15(45)
231	GO:0003824	catalytic activity	6/13(47)
3527	GO:0046872	metal ion binding	1/2(9)
233	GO:0005178	integrin binding	1/10(46)
233	GO:0005201	extracellular matrix structural constituent	1/10(46)
1050	GO:0015269	calcium-activated potassium channel activity	3/4(20)
2798	GO:0008113	peptide-methionine (S)-S-oxide reductase activity	1/2(9)
2134	GO:0003682	chromatin binding	2/4(14)
529	GO:0000166	nucleotide binding	7/7(28)
878	GO:0005615	extracellular space	1/7(23)
878	GO:0004866	endopeptidase inhibitor activity	5/7(23)
49	GO:0003777	microtubule motor activity	11/30(138)
119	GO:0016787	hydrolase activity	4/22(75)
119	GO:0042043	neurexin family protein binding	4/22(75)
119	GO:0003990	acetylcholinesterase activity	2/22(75)
119	GO:0004771	sterol esterase activity	1/22(75)
1193	GO:0004843	thiol-dependent ubiquitin-specific protease activity	1/3(18)
873	GO:0005078	MAP-kinase scaffold activity	1/4(23)
870	GO:0000166	nucleotide binding	3/6(23)
956	GO:0050770	regulation of axonogenesis	2/5(21)
1	GO:0001223	transcription coactivator binding	2/267(729)
1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	3/267(729)
1	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/267(729)
1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	6/267(729)
1	GO:0003676	nucleic acid binding	66/267(729)
1	GO:0001046	core promoter sequence-specific DNA binding	1/267(729)
1	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9/267(729)
1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	2/267(729)
1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/267(729)
2001	GO:0003677	DNA binding	3/3(15)
1112	GO:0008022	protein C-terminus binding	1/5(19)
2745	GO:0004843	thiol-dependent ubiquitin-specific protease activity	2/2(10)
2509	GO:0005654	nucleoplasm	2/4(11)
2508	GO:0004842	ubiquitin-protein transferase activity	1/2(11)
3079	GO:0004222	metalloendopeptidase activity	1/1(9)
78	GO:0005216	ion channel activity	2/14(103)
78	GO:0005245	voltage-gated calcium channel activity	1/14(103)
2039	GO:0000993	RNA polymerase II core binding	1/5(15)
2379	GO:0004046	aminoacylase activity	2/4(12)
2379	GO:0016020	membrane	1/4(12)
774	GO:0015909	long-chain fatty acid transport	2/4(24)
2423	GO:0019863	IgE binding	1/4(11)
2876	GO:0003824	catalytic activity	2/2(9)
140	GO:0000150	recombinase activity	1/6(64)
140	GO:0000166	nucleotide binding	2/6(64)
2676	GO:0002053	positive regulation of mesenchymal cell proliferation	1/2(10)
1179	GO:0009267	cellular response to starvation	2/4(18)
615	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/6(26)
2151	GO:0005344	oxygen transporter activity	3/6(14)
75	GO:0005179	hormone activity	2/25(107)
75	GO:0005125	cytokine activity	2/25(107)
75	GO:0004745	retinol dehydrogenase activity	1/25(107)
75	GO:0008083	growth factor activity	11/25(107)
8556	GO:0003723	RNA binding	1/2(6)
5204	GO:0016020	membrane	1/1(8)
70	GO:0004871	signal transducer activity	15/23(109)
8140	GO:0016020	membrane	1/2(7)
462	GO:0005576	extracellular region	3/9(31)
462	GO:0042802	identical protein binding	3/9(31)
8414	GO:0001948	glycoprotein binding	1/2(7)
2122	GO:0003676	nucleic acid binding	2/4(14)
48	GO:0004842	ubiquitin-protein transferase activity	18/35(139)
48	GO:0003713	transcription coactivator activity	2/35(139)
80	GO:0005215	transporter activity	7/26(103)
1282	GO:0001102	RNA polymerase II activating transcription factor binding	2/4(17)
705	GO:0005085	guanyl-nucleotide exchange factor activity	1/6(25)
8514	GO:0019902	phosphatase binding	1/2(6)
261	GO:0000166	nucleotide binding	6/11(42)
2240	GO:0016020	membrane	1/4(13)
1366	GO:0044822	poly(A) RNA binding	4/4(17)
356	GO:0003714	transcription corepressor activity	1/9(34)
356	GO:0008270	zinc ion binding	1/9(34)
260	GO:0005244	voltage-gated ion channel activity	3/11(42)
260	GO:0004602	glutathione peroxidase activity	2/11(42)
353	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/8(34)
353	GO:0003677	DNA binding	1/8(34)
12	GO:0004930	G-protein coupled receptor activity	6/93(341)
12	GO:0004871	signal transducer activity	51/93(341)
12	GO:0001626	nociceptin receptor activity	2/93(341)
12	GO:0001596	angiotensin type I receptor activity	2/93(341)
12	GO:0003779	actin binding	2/93(341)
12	GO:0001965	G-protein alpha-subunit binding	1/93(341)
12	GO:0002020	protease binding	2/93(341)
2981	GO:0045892	negative regulation of transcription, DNA-templated	1/2(9)
990	GO:0048706	embryonic skeletal system development	1/5(21)
9239	GO:0004175	endopeptidase activity	1/1(5)

Node PARADISAEA / Paradisaea rubra

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