BOP - Node FICEDULA

Node summary

Genes	15387
Ancestral node	BOP1

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CAFE summary

Expansions	329 (23 rapid)
Contractions	560 (7 rapid)
Extinctions	194

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Family list

GO Terms

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Family ID	Gene Count	Change	Rapid (*)?	Exctinction (--)?

5980	0	-1		--
271	4	-1
273	3	-1
274	7	+2
276	3	-2
279	4	-1
9256	0	-1		--
9253	0	-1		--
2142	1	-1
2684	3	+2
2686	1	-1
99	7	-3
98	9	-1
91	13	+1
90	17	+1
92	11	-1
94	13	+6	*
96	10	-1
1172	1	-1
1170	4	+2
620	4	+1
8019	0	-1		--
627	4	+1
871	2	-1
625	4	+1
2036	1	-1
2749	1	-1
8291	0	-1		--
393	5	+1
398	3	-1
2301	3	+1
5840	2	+1
179	5	-1
176	6	-1
172	8	+1
693	4	+1
259	2	-2
252	3	-1
250	4	-2
3683	2	+1
3687	2	+1
2516	2	+1
8037	0	-1		--
8038	0	-1		--
8525	0	-1		--
2181	1	-1
2180	1	-1
2188	1	-1
155	8	+1
157	6	-1
159	3	-3	*
8133	0	-1		--
2723	2	+1
8862	0	-1		--
814	2	-1
1707	1	-1
2096	1	-1
2093	1	-1
3029	2	+1
3025	2	+1
3022	2	+1
8738	0	-1		--
8739	0	-1		--
8734	0	-1		--
4199	2	+1
239	6	+1
234	4	-2
235	5	-1
236	6	+1
237	12	+7	*
231	5	-1
939	2	-1
938	2	-1
9567	0	-1		--
932	2	-1
931	2	-1
930	2	-1
796	2	-1
2145	1	-1
799	13	+11	*
2144	4	+2
1137	3	+1
8052	0	-1		--
8503	2	+1
8509	0	-1		--
8508	0	-1		--
2	79	+2
3277	2	+1
1927	1	-1
2411	2	+1
9714	0	-1		--
9004	0	-1		--
9001	0	-1		--
3313	2	+1
1588	3	+1
3315	2	+1
9454	0	-1		--
8633	0	-1		--
9451	0	-1		--
2416	1	-1
214	7	+1
212	3	-1
213	7	+1
219	4	-1
2550	1	-1
2551	5	+1
2552	2	+1
919	2	-1
910	5	+2
913	2	-1
8079	0	-1		--
1111	2	-1
1110	8	+4
1114	8	+4	*
194	10	+4
196	3	-3	*
190	7	+1
192	5	-1
2768	2	+1
2763	2	+1
9739	0	-1		--
3450	2	+1
6	49	-3
3064	2	+1
1301	3	+1
1308	3	+1
7756	0	-1		--
3665	2	+1
2579	3	+2
2574	2	+1
975	4	+1
973	2	-1
978	2	-1
1466	3	+1
319	3	-2
312	9	+5	*
310	3	-1
317	3	-1
314	4	-1
443	3	-1
441	3	-1
8697	2	+1
8124	3	+2	*
3430	2	+1
2744	2	+1
2746	1	-1
5204	0	-1		--
3041	0	-1		--
3042	2	+1
1095	1	-1
1090	2	-1
1091	3	+1
1093	3	+1
1320	3	+1
1321	3	+1
1328	3	+1
8351	0	-1		--
8352	0	-1		--
8354	0	-1		--
959	5	+2
9670	2	+1
8901	0	-1		--
6841	2	+1
591	3	-1
5415	0	-1		--
5417	0	-1		--
5418	2	+1
5419	2	+1
1407	3	+1
1491	3	+1
1540	4	+2
335	1	-1
334	1	-2
330	3	-2
332	3	-1
9446	2	+1
9444	2	+1
2014	4	+2
2017	3	+1
2010	1	-1
9035	0	-1		--
1343	3	+1
454	3	-1
7714	0	-1		--
8377	0	-1		--
833	4	+2
8074	0	-1		--
4002	0	-1		--
2465	0	-1		--
9656	2	+1
9303	0	-1		--
579	3	-1
578	4	+1
572	2	-1
576	2	-1
2800	2	+1
8583	0	-1		--
8585	0	-1		--
355	3	-1
351	2	-1
2259	1	-1
2254	3	+2
2073	1	-1
2076	1	-1
8790	0	-1		--
3220	2	+1
8410	2	+1
8395	0	-1		--
8391	0	-1		--
8392	0	-1		--
3194	2	+1
3198	2	+1
8999	0	-1		--
298	4	-1
296	4	-1
297	3	-2
294	4	-1
293	4	-1
291	6	+1
2442	1	-1
2444	3	+2
2445	1	-1
7862	0	-1		--
9632	0	-1		--
1432	1	-1
559	3	-1
2866	2	+1
555	3	-1
557	5	+1
550	2	-1
553	2	-1
1438	3	+1
1194	3	+1
459	3	-1
376	5	+1
7980	0	-1		--
7986	0	-1		--
7987	0	-1		--
8150	2	+1
8151	0	-1		--
413	3	-1
2428	0	-1		--
2420	0	-1		--
7846	0	-1		--
9342	2	+1
1813	1	-1
1818	3	+1
2165	1	-1
2164	1	-1
2166	5	+3
1975	1	-1
2162	1	-1
2847	3	+2	*
536	1	-1
533	3	-1
1905	1	-1
1902	1	-1
3813	2	+1
3810	2	+1
3811	2	+1
3818	2	+1
2984	2	+1
1014	1	-1
1017	0	-2	*	--
1012	1	-1
439	3	-1
9497	0	-1		--
1054	1	-2
7826	0	-1		--
1055	2	-1
3790	2	+1
2404	1	-1
2157	1	-1
2400	1	-1
3243	2	+1
1990	4	+2
1482	1	-1
1484	3	+1
10611	0	-1		--
1992	1	-1
510	3	-1
512	4	+1
515	2	-1
514	2	-1
517	2	-1
1220	4	+1
8796	0	-1		--
3874	2	+1
3877	2	+1
2238	3	+1
2234	1	-1
2236	1	-1
3498	2	+1
2090	1	-1
3	65	-3
7029	0	-1		--
3331	2	+1
3330	0	-1		--
7792	0	-1		--
7795	0	-1		--
7796	0	-1		--
1038	1	-2
1039	3	+1
1032	2	-1
1030	2	-1
1034	4	+2
2397	3	+1
2395	1	-1
2170	1	-1
4963	2	+1
1930	1	-1
1938	0	-2		--
600	3	-1
8274	0	-1		--
8272	0	-1		--
8108	0	-1		--
8419	0	-1		--
7580	0	-1		--
7583	0	-1		--
3850	2	+1
10026	2	+1
10025	2	+1
10022	2	+1
744	2	-1
1051	2	-1
3111	2	+1
2137	1	-1
7	46	-6
2134	1	-1
2371	3	+1
2372	2	+1
2133	1	-1
2113	1	-1
883	1	-1
882	2	-1
884	2	-1
9583	0	-1		--
10019	2	+1
9239	0	-1		--
663	4	+1
8780	0	-1		--
3283	2	+1
8430	0	-1		--
8517	0	-1		--
4128	0	-1		--
4127	0	-1		--
2639	2	+1
2638	2	+1
2635	1	-1
2630	1	-1
10262	0	-1		--
10266	0	-1		--
9043	0	-1		--
9040	0	-1		--
9047	0	-1		--
3548	2	+1
2966	2	+1
763	2	-1
1078	2	-1
1079	1	-2
3137	2	+1
3132	2	+1
2353	1	-1
2350	3	+1
3737	0	-1		--
3736	2	+1
3734	2	+1
2787	2	+1
9690	0	-1		--
9691	0	-1		--
8257	0	-1		--
666	4	+1
6845	0	-1		--
7634	0	-1		--
1025	2	-1
3891	6	+5	*
9063	0	-1		--
9062	0	-1		--
3566	2	+1
2902	2	+1
708	2	-1
147	5	-2
705	2	-1
3152	2	+1
1982	1	-1
1983	1	-1
1266	3	+1
8575	0	-1		--
8576	0	-1		--
8578	0	-1		--
2338	2	+1
120	7	-1
124	7	-1
126	10	+1
128	6	-1
7951	0	-1		--
8818	0	-1		--
8217	0	-1		--
8216	2	+1
1997	1	-1
9569	0	-1		--
3392	2	+1
1510	1	-1
8899	0	-1		--
262	6	+1
265	6	+1
269	1	-2
987	4	+1
9081	2	+1
2677	1	-1
1208	1	-1
3177	2	+1
725	4	+1
720	2	-2
1163	3	+1
2035	3	+1
472	3	-1
471	5	+2
474	3	-1
2033	1	-1
8550	0	-1		--
8004	0	-1		--
8000	0	-1		--
8002	0	-1		--
2030	1	-1
2319	2	+1
2314	1	-1
2315	10	+9	*
2312	0	-2		--
3774	0	-1		--
7888	0	-1		--
103	10	-1
101	14	+4	*
107	11	+1
104	24	+16	*
7265	0	-1		--
9745	0	-1		--
8838	0	-1		--
8834	0	-1		--
9595	0	-1		--
688	2	-1
8762	0	-1		--
684	4	+1
686	5	+2
683	2	-1
8505	2	+1
244	4	-2
246	3	-2
240	4	-1
243	4	-1
242	4	-1
249	4	-1
9246	0	-1		--
3695	2	+1
3696	2	+1
338	3	-1
2696	3	+2
2691	1	-1
2152	1	-1
1141	3	+1
1148	1	-1
1149	3	+1
768	2	-1
336	6	+1
8020	0	-1		--
381	1	-3	*
383	6	+1
384	5	+1
385	2	-1
389	3	-1
3758	2	+1
3753	2	+1
2191	3	+2	*
164	6	-1
165	11	+1
161	4	-2
163	6	-1
9184	0	-1		--
805	2	-1
804	2	-1
5604	2	+1
228	5	-1
223	7	+1
222	4	-1
221	7	+1
220	4	-2
2507	1	-1
2505	2	+1
2504	2	+1
2500	0	-1		--
3206	2	+1
3203	2	+1
8043	0	-1		--
8045	0	-1		--
2704	2	+1
144	8	-1
142	6	-1
140	3	-1
2715	1	-1
6248	0	-1		--
8878	0	-1		--
828	2	-1
822	2	-1
8162	0	-1		--
3012	2	+1
11	47	+1
10	62	+10	*
13	36	-5
12	47	+3
15	33	-5
14	36	-3
17	26	-5
16	31	-2
19	26	-4
18	33	+1
6742	0	-1		--
200	4	-1
203	8	+2
202	7	+1
204	5	-1
206	5	-1
830	2	-1
3650	2	+1
2527	1	-1
2528	2	+1
929	2	-1
920	7	+4	*
922	2	-1
923	2	-1
924	2	-1
927	2	-1
784	2	-1
788	4	+1
1373	1	-1
402	2	-1
8068	0	-1		--
2890	2	+1
1106	2	-1
1100	2	-1
1109	4	+1
4	62	+3
2775	2	+1
2777	1	-1
843	2	-1
2407	2	+1
3079	0	-1		--
5645	0	-1		--
488	3	-1
482	3	-1
481	3	-1
3679	2	+1
3676	2	+1
1457	3	+1
3588	2	+1
902	2	-1
903	2	-1
901	2	-1
907	2	-1
904	2	-1
905	2	-1
909	4	+1
3293	2	+1
1691	1	-1
1470	3	+1
24	25	-3
25	34	+3
26	81	+16	*
27	21	-2
20	28	-2
21	29	-1
22	26	-1
28	19	-2
29	22	-1
1063	2	-1
1064	4	+1
1066	1	-1
2283	1	-1
2286	1	-1
2056	1	-1
9122	0	-1		--
8312	0	-1		--
8231	0	-1		--
7917	0	-1		--
182	6	-1
183	8	+1
180	5	-2
186	6	-1
187	6	-1
184	2	-3	*
188	7	+1
189	3	-2
9405	2	+1
869	2	-1
863	2	-1
866	2	-1
2020	2	+1
8	48	-5
1319	3	+1
1318	3	+1
7724	0	-1		--
7726	0	-1		--
6709	2	+1
3613	2	+1
2569	2	+1
2560	3	+2	*
961	2	-1
963	2	-1
968	2	-1
969	1	-1
1240	3	+1
1248	1	-1
5195	0	-1		--
8911	0	-1		--
1676	3	+1
1413	3	+1
308	4	-1
309	3	-1
300	3	-1
303	4	-1
304	8	+1
305	11	+5	*
306	4	-1
470	3	-1
9100	2	+1
9141	0	-1		--
3429	2	+1
3423	2	+1
2000	1	-1
8626	0	-1		--
8620	0	-1		--
1904	1	-1
1332	3	+1
39	23	+2
38	20	+1
31	13	-2
30	19	-1
37	19	-1
36	13	-4
34	23	+1
3466	2	+1
3635	2	+1
8769	0	-1		--
948	2	-1
949	3	+1
947	2	-1
944	2	-1
945	2	-1
942	2	-1
940	7	+3	*
2410	2	+1
9667	2	+1
9665	3	+2	*
9669	3	+2	*
588	0	-1		--
589	3	-1
2837	2	+1
2127	1	-1
320	4	-1
321	5	+1
325	4	-1
3076	2	+1
2248	3	+2	*
2246	1	-1
2241	1	-1
10069	0	-1		--
3401	2	+1
2068	2	-1
469	3	-1
465	3	-1
464	3	-1
467	3	-1
8367	0	-1		--
10289	0	-1		--
1446	3	+1
283	6	+1
284	4	-1
2475	1	-1
2474	2	+1
7871	0	-1		--
7872	0	-1		--
6308	2	+1
10420	0	-1		--
9646	2	+1
8950	0	-1		--
3218	2	+1
48	16	-1
49	15	-1
46	17	-1
47	16	-1
45	19	+1
42	21	+1
43	4	-9	*
40	20	+1
41	12	-6	*
341	5	+1
8755	0	-1		--
9439	2	+1
8751	0	-1		--
2042	1	-1
2040	1	-1
2041	1	-1
9413	4	+3	*
8237	0	-1		--
8385	0	-1		--
406	3	-1
1372	3	+1
4032	2	+1
2455	3	+1
7851	0	-1		--
7857	0	-1		--
7859	0	-1		--
3089	2	+1
9290	0	-1		--
3354	2	+1
541	3	-1
546	3	-1
549	4	+1
3821	2	+1
369	3	-1
2200	1	-1
9486	0	-1		--
7999	0	-1		--
7998	0	-1		--
8141	2	+1
8143	0	-1		--
59	16	+1
55	11	-4
54	19	+3
57	15	-1
56	15	-1
51	14	-3
50	21	+1
53	19	+1
52	18	+1
2997	2	+1
428	3	-1
420	3	-1
424	5	+1
427	3	-1
850	4	+1
851	2	-1
2331	2	+1
2336	1	-1
9601	3	+2
10176	0	-1		--
1943	1	-1
1944	1	-1
2855	2	+1
523	4	+1
529	3	-1
1236	3	+1
1237	1	-1
1964	1	-1
3809	2	+1
3807	2	+1
3801	2	+1
4178	0	-1		--
2229	3	+1
2226	1	-1
10053	0	-1		--
2082	1	-1
2083	1	-1
2086	2	+1
2085	1	-1
9130	0	-1		--
7781	0	-1		--
1008	1	-1
1007	1	-1
1006	4	+1
1004	1	-1
8616	0	-1		--
9274	0	-1		--
7817	0	-1		--
7812	0	-1		--
2666	0	-1		--
2661	1	-1
61	12	-1
63	11	-2
65	11	-3
67	9	-3
69	10	-4
508	2	-1
503	4	+1
501	5	+1
637	5	+1
3865	2	+1
2600	2	+1
2602	1	-1
10035	0	-1		--
10034	0	-1		--
7371	2	+1
753	2	-1
2958	2	+1
2956	2	+1
1802	1	-1
5344	2	+1
3103	2	+1
5	64	+2
8674	0	-1		--
8098	0	-1		--
2388	1	-1
2129	1	-1
3295	2	+1
1279	1	-1
1270	3	+1
611	2	-1
8249	0	-1		--
8247	0	-1		--
3332	0	-1		--
10658	0	-1		--
2593	2	+1
2599	1	-1
9051	0	-1		--
77	12	-1
76	11	-1
75	14	+1
74	13	-1
72	15	+2
71	13	-1
78	6	-3
1049	1	-2
3124	2	+1
8654	0	-1		--
862	2	-1
2755	1	-1
2320	0	-1		--
2367	2	+1
1863	1	-1
2100	4	+1
9	47	-1
890	4	+1
895	7	+5
1787	1	-1
675	4	+1
676	4	+1
1966	1	-1
10072	0	-1		--
2641	2	+1
2647	1	-1
9071	2	+1
3557	2	+1
4327	2	+1
3144	2	+1
2067	1	-1
2121	1	-1
2123	1	-1
132	5	-2
131	6	-1
130	6	-2
136	9	+1
135	7	-1
134	7	-1
139	7	-1
138	5	-2
1	119	+7
82	11	-2
80	10	-3
81	12	-1
86	12	-1
85	11	-2
9193	0	-1		--
9195	2	+1
3368	2	+1
3887	2	+1
3881	2	+1
3883	2	+1
3889	2	+1
992	5	+3	*
7399	0	-1		--
10051	0	-1		--
9099	2	+1
2154	1	-1
2155	3	+1
2402	2	-1
8564	0	-1		--
8560	0	-1		--
2329	2	+1
115	9	-1
116	7	-3
112	9	-1
118	8	-1
8005	0	-1		--
8003	0	-1		--
8770	0	-1		--
8777	0	-1		--
7641	0	-1		--
9016	0	-1		--
1298	3	+1
8484	0	-1		--

Family ID	GO ID	GO term	# genes w/ GO ID

1943	GO:0003743	translation initiation factor activity	2/3(15)
341	GO:0003824	catalytic activity	3/9(35)
341	GO:0005739	mitochondrion	1/9(35)
3850	GO:0050861	positive regulation of B cell receptor signaling pathway	1/3(9)
814	GO:0043515	kinetochore binding	1/5(23)
814	GO:0002162	dystroglycan binding	1/5(23)
8626	GO:0002038	positive regulation of L-glutamate transport	1/1(6)
2855	GO:0043184	vascular endothelial growth factor receptor 2 binding	1/3(9)
1491	GO:0004896	cytokine receptor activity	2/5(17)
3331	GO:0008168	methyltransferase activity	1/3(9)
1707	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/3(16)
2314	GO:0004672	protein kinase activity	1/3(13)
1064	GO:0005200	structural constituent of cytoskeleton	1/7(19)
910	GO:0000166	nucleotide binding	4/8(22)
427	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/7(32)
427	GO:0003676	nucleic acid binding	3/7(32)
298	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/8(38)
298	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/8(38)
298	GO:0003677	DNA binding	2/8(38)
296	GO:0005096	GTPase activator activity	1/10(39)
296	GO:0008289	lipid binding	2/10(39)
296	GO:0007165	signal transduction	2/10(39)
297	GO:0005096	GTPase activator activity	3/8(39)
294	GO:0003677	DNA binding	3/9(39)
293	GO:0007165	signal transduction	3/9(39)
293	GO:0005042	netrin receptor activity	2/9(39)
291	GO:0005215	transporter activity	7/11(39)
291	GO:0005212	structural constituent of eye lens	1/11(39)
591	GO:0005516	calmodulin binding	4/7(27)
8237	GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	1/1(7)
3774	GO:0005179	hormone activity	1/1(9)
968	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/5(21)
968	GO:0003677	DNA binding	2/5(21)
190	GO:0005125	cytokine activity	3/13(51)
190	GO:0008009	chemokine activity	4/13(51)
192	GO:0003779	actin binding	7/11(51)
271	GO:0005178	integrin binding	1/9(41)
271	GO:0005509	calcium ion binding	2/9(41)
271	GO:0001968	fibronectin binding	2/9(41)
271	GO:0005006	epidermal growth factor-activated receptor activity	2/9(41)
273	GO:0000975	regulatory region DNA binding	1/7(41)
273	GO:0003677	DNA binding	4/7(41)
274	GO:0004062	aryl sulfotransferase activity	2/12(41)
274	GO:0004027	alcohol sulfotransferase activity	1/12(41)
274	GO:0008146	sulfotransferase activity	5/12(41)
276	GO:0005085	guanyl-nucleotide exchange factor activity	4/8(41)
279	GO:0015031	protein transport	5/9(40)
279	GO:0006887	exocytosis	2/9(40)
1904	GO:0046873	metal ion transmembrane transporter activity	1/3(15)
1904	GO:0005385	zinc ion transmembrane transporter activity	1/3(15)
3676	GO:0003824	catalytic activity	2/3(9)
3025	GO:0005215	transporter activity	1/3(9)
5418	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	2/3(8)
2984	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/3(9)
8739	GO:0042803	protein homodimerization activity	1/1(6)
1014	GO:0005886	plasma membrane	1/4(20)
2388	GO:0005524	ATP binding	1/3(12)
8734	GO:0007017	microtubule-based process	1/1(6)
1407	GO:0003677	DNA binding	3/5(17)
529	GO:0000166	nucleotide binding	7/7(28)
1012	GO:0003713	transcription coactivator activity	1/3(20)
1012	GO:0000398	mRNA splicing, via spliceosome	1/3(20)
2768	GO:0006915	apoptotic process	1/3(10)
4199	GO:0050908	detection of light stimulus involved in visual perception	2/3(8)
443	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/7(32)
443	GO:0003677	DNA binding	1/7(32)
441	GO:0004871	signal transducer activity	3/7(32)
9253	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	1/1(5)
1332	GO:0004672	protein kinase activity	1/5(17)
1332	GO:0000166	nucleotide binding	3/5(17)
103	GO:0005215	transporter activity	1/21(87)
103	GO:0000166	nucleotide binding	4/21(87)
101	GO:0016020	membrane	2/23(89)
107	GO:0005198	structural molecule activity	13/21(83)
104	GO:0004930	G-protein coupled receptor activity	2/28(87)
104	GO:0004871	signal transducer activity	3/28(87)
902	GO:0061631	ubiquitin conjugating enzyme activity	2/5(22)
903	GO:0003697	single-stranded DNA binding	1/5(22)
903	GO:0000166	nucleotide binding	1/5(22)
39	GO:0001948	glycoprotein binding	2/43(155)
39	GO:0005198	structural molecule activity	14/43(155)
901	GO:0005509	calcium ion binding	2/5(22)
2042	GO:0000166	nucleotide binding	3/3(15)
907	GO:0004386	helicase activity	1/6(22)
907	GO:0000166	nucleotide binding	4/6(22)
904	GO:0001605	adrenomedullin receptor activity	2/5(22)
904	GO:0004871	signal transducer activity	2/5(22)
905	GO:0008375	acetylglucosaminyltransferase activity	1/5(22)
905	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	4/5(22)
31	GO:0004252	serine-type endopeptidase activity	2/24(171)
31	GO:0001964	startle response	2/24(171)
31	GO:0016020	membrane	2/24(171)
31	GO:0008344	adult locomotory behavior	2/24(171)
31	GO:0003682	chromatin binding	1/24(171)
909	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	3/7(22)
37	GO:0003700	transcription factor activity, sequence-specific DNA binding	2/39(156)
37	GO:0005102	receptor binding	22/39(156)
37	GO:0003714	transcription corepressor activity	2/39(156)
37	GO:0005096	GTPase activator activity	1/39(156)
36	GO:0005112	Notch binding	10/30(160)
36	GO:0001047	core promoter binding	1/30(160)
36	GO:0005509	calcium ion binding	5/30(160)
34	GO:0001948	glycoprotein binding	1/45(166)
34	GO:0005178	integrin binding	1/45(166)
34	GO:0005102	receptor binding	2/45(166)
34	GO:0005509	calcium ion binding	28/45(166)
1240	GO:0004930	G-protein coupled receptor activity	3/5(17)
439	GO:0000166	nucleotide binding	4/8(32)
2165	GO:0042803	protein homodimerization activity	1/3(14)
1248	GO:0035091	phosphatidylinositol binding	1/4(17)
1248	GO:0001654	eye development	1/4(17)
1248	GO:0010314	phosphatidylinositol-5-phosphate binding	1/4(17)
2166	GO:0006904	vesicle docking involved in exocytosis	3/7(14)
2162	GO:0003723	RNA binding	3/3(14)
338	GO:0016491	oxidoreductase activity	2/10(35)
338	GO:0004362	glutathione-disulfide reductase activity	1/10(35)
338	GO:0004791	thioredoxin-disulfide reductase activity	5/10(35)
3807	GO:0002039	p53 binding	3/3(9)
336	GO:0003824	catalytic activity	5/12(36)
336	GO:0001105	RNA polymerase II transcription coactivator activity	1/12(36)
3801	GO:0043652	engulfment of apoptotic cell	1/3(9)
330	GO:0005216	ion channel activity	2/8(36)
332	GO:0055085	transmembrane transport	3/8(36)
332	GO:0015136	sialic acid transmembrane transporter activity	2/8(36)
1372	GO:0016491	oxidoreductase activity	2/5(17)
559	GO:0046983	protein dimerization activity	3/7(27)
559	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/7(27)
559	GO:0001102	RNA polymerase II activating transcription factor binding	1/7(27)
9632	GO:0016020	membrane	1/1(4)
1905	GO:0003779	actin binding	2/3(15)
1902	GO:0005634	nucleus	2/3(15)
3293	GO:0019899	enzyme binding	1/3(9)
3450	GO:0016020	membrane	2/3(9)
850	GO:0000166	nucleotide binding	1/7(23)
851	GO:0030306	ADP-ribosylation factor binding	1/5(23)
6	GO:0005200	structural constituent of cytoskeleton	1/103(437)
6	GO:1990126	retrograde transport, endosome to plasma membrane	2/103(437)
6	GO:0007165	signal transduction	2/103(437)
6	GO:0003676	nucleic acid binding	2/103(437)
6	GO:0003950	NAD+ ADP-ribosyltransferase activity	2/103(437)
6	GO:0035556	intracellular signal transduction	1/103(437)
6	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1/103(437)
6	GO:0000149	SNARE binding	1/103(437)
6	GO:0019887	protein kinase regulator activity	1/103(437)
6	GO:0004672	protein kinase activity	2/103(437)
6	GO:0008134	transcription factor binding	2/103(437)
6	GO:0090090	negative regulation of canonical Wnt signaling pathway	3/103(437)
6	GO:0044212	transcription regulatory region DNA binding	1/103(437)
6	GO:0005216	ion channel activity	2/103(437)
6	GO:0017137	Rab GTPase binding	1/103(437)
6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/103(437)
6	GO:0045893	positive regulation of transcription, DNA-templated	2/103(437)
6	GO:0007520	myoblast fusion	2/103(437)
6	GO:0001085	RNA polymerase II transcription factor binding	2/103(437)
6	GO:0010613	positive regulation of cardiac muscle hypertrophy	1/103(437)
6	GO:0008093	cytoskeletal adaptor activity	1/103(437)
6	GO:0016567	protein ubiquitination	3/103(437)
6	GO:0005634	nucleus	2/103(437)
2684	GO:0016020	membrane	2/4(10)
2684	GO:0001772	immunological synapse	1/4(10)
99	GO:0005085	guanyl-nucleotide exchange factor activity	9/19(91)
98	GO:0015171	amino acid transmembrane transporter activity	16/19(91)
91	GO:0042813	Wnt-activated receptor activity	1/25(96)
91	GO:0004888	transmembrane signaling receptor activity	12/25(96)
90	GO:0005198	structural molecule activity	18/37(97)
92	GO:0008028	monocarboxylic acid transmembrane transporter activity	8/23(96)
92	GO:0055085	transmembrane transport	9/23(96)
92	GO:0046415	urate metabolic process	1/23(96)
96	GO:0004725	protein tyrosine phosphatase activity	3/21(93)
96	GO:0004722	protein serine/threonine phosphatase activity	1/21(93)
96	GO:0030234	enzyme regulator activity	1/21(93)
96	GO:0004438	phosphatidylinositol-3-phosphatase activity	6/21(93)
1990	GO:0004867	serine-type endopeptidase inhibitor activity	1/5(15)
1992	GO:0003824	catalytic activity	1/3(15)
1997	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/3(15)
1997	GO:0000989	transcription factor activity, transcription factor binding	1/3(15)
8901	GO:0044822	poly(A) RNA binding	1/1(6)
8654	GO:0003677	DNA binding	1/1(6)
969	GO:0008289	lipid binding	2/3(21)
8834	GO:0008289	lipid binding	1/1(6)
744	GO:0005085	guanyl-nucleotide exchange factor activity	2/5(24)
2866	GO:0016020	membrane	1/2(9)
555	GO:0006457	protein folding	2/7(27)
555	GO:0005509	calcium ion binding	3/7(27)
557	GO:0001609	G-protein coupled adenosine receptor activity	1/9(27)
557	GO:0004930	G-protein coupled receptor activity	1/9(27)
557	GO:0004871	signal transducer activity	4/9(27)
3635	GO:0003743	translation initiation factor activity	2/3(9)
550	GO:0016307	phosphatidylinositol phosphate kinase activity	2/5(28)
553	GO:0003723	RNA binding	3/4(28)
239	GO:0003677	DNA binding	7/9(44)
3064	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	2/3(9)
234	GO:0003677	DNA binding	4/11(46)
235	GO:0015186	L-glutamine transmembrane transporter activity	2/11(46)
235	GO:0016020	membrane	4/11(46)
235	GO:0005290	L-histidine transmembrane transporter activity	1/11(46)
235	GO:0015171	amino acid transmembrane transporter activity	2/11(46)
235	GO:0005886	plasma membrane	1/11(46)
236	GO:0008378	galactosyltransferase activity	6/10(45)
237	GO:0016740	transferase activity	2/15(45)
237	GO:0004307	ethanolaminephosphotransferase activity	1/15(45)
231	GO:0003824	catalytic activity	6/13(47)
1051	GO:0005267	potassium channel activity	2/5(20)
1051	GO:0005249	voltage-gated potassium channel activity	2/5(20)
1054	GO:0004674	protein serine/threonine kinase activity	1/4(20)
1054	GO:0000166	nucleotide binding	2/4(20)
1055	GO:0007029	endoplasmic reticulum organization	1/5(20)
2229	GO:0005102	receptor binding	1/4(13)
1194	GO:0001104	RNA polymerase II transcription cofactor activity	3/5(18)
1	GO:0001223	transcription coactivator binding	2/267(729)
1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	3/267(729)
1	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/267(729)
1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	6/267(729)
1	GO:0003676	nucleic acid binding	66/267(729)
1	GO:0001046	core promoter sequence-specific DNA binding	1/267(729)
1	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9/267(729)
1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	2/267(729)
1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/267(729)
8162	GO:0016020	membrane	1/1(7)
142	GO:0000166	nucleotide binding	6/13(63)
1172	GO:0005518	collagen binding	2/3(18)
140	GO:0000150	recombinase activity	1/6(64)
140	GO:0000166	nucleotide binding	2/6(64)
1170	GO:0000166	nucleotide binding	1/6(18)
1270	GO:0006810	transport	2/5(17)
611	GO:0004842	ubiquitin-protein transferase activity	3/5(26)
8249	GO:0005179	hormone activity	1/1(7)
8247	GO:0000166	nucleotide binding	1/1(7)
2123	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism	2/3(14)
1004	GO:0008270	zinc ion binding	1/3(20)
2127	GO:0000166	nucleotide binding	2/3(14)
947	GO:0003677	DNA binding	4/5(22)
944	GO:0005737	cytoplasm	2/5(22)
944	GO:0098641	cadherin binding involved in cell-cell adhesion	1/5(22)
945	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/5(22)
945	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/5(22)
942	GO:0070062	extracellular exosome	1/5(22)
3111	GO:0000166	nucleotide binding	2/3(9)
2085	GO:0001106	RNA polymerase II transcription corepressor activity	2/3(14)
1470	GO:0008270	zinc ion binding	4/5(17)
2372	GO:0019905	syntaxin binding	2/3(12)
684	GO:0050807	regulation of synapse organization	2/6(25)
686	GO:0005096	GTPase activator activity	2/8(25)
1301	GO:0007155	cell adhesion	1/5(17)
1301	GO:0019960	C-X3-C chemokine binding	2/5(17)
2715	GO:0005216	ion channel activity	1/3(10)
8385	GO:0004758	serine C-palmitoyltransferase activity	1/1(7)
1308	GO:0005102	receptor binding	2/4(17)
549	GO:0008307	structural constituent of muscle	1/7(28)
549	GO:0005623	cell	1/7(28)
549	GO:0006936	muscle contraction	2/7(28)
131	GO:0005216	ion channel activity	7/13(69)
131	GO:0005249	voltage-gated potassium channel activity	1/13(69)
130	GO:0001849	complement component C1q binding	1/14(69)
130	GO:0005178	integrin binding	1/14(69)
130	GO:0005201	extracellular matrix structural constituent	2/14(69)
130	GO:0005509	calcium ion binding	1/14(69)
136	GO:0090022	regulation of neutrophil chemotaxis	2/17(65)
136	GO:0005886	plasma membrane	2/17(65)
136	GO:0004385	guanylate kinase activity	1/17(65)
136	GO:0005654	nucleoplasm	1/17(65)
136	GO:0019904	protein domain specific binding	4/17(65)
136	GO:0004672	protein kinase activity	2/17(65)
8019	GO:0005102	receptor binding	1/1(7)
134	GO:0000166	nucleotide binding	8/14(66)
139	GO:0003677	DNA binding	1/16(64)
139	GO:0000166	nucleotide binding	13/16(64)
138	GO:0014719	skeletal muscle satellite cell activation	2/12(64)
138	GO:0005509	calcium ion binding	1/12(64)
24	GO:0008233	peptidase activity	2/54(230)
24	GO:0004175	endopeptidase activity	4/54(230)
24	GO:0004222	metalloendopeptidase activity	16/54(230)
25	GO:0004930	G-protein coupled receptor activity	13/66(229)
25	GO:0001631	cysteinyl leukotriene receptor activity	2/66(229)
25	GO:0001965	G-protein alpha-subunit binding	1/66(229)
25	GO:0001530	lipopolysaccharide binding	2/66(229)
25	GO:0004871	signal transducer activity	24/66(229)
26	GO:0005200	structural constituent of cytoskeleton	54/166(216)
27	GO:0000166	nucleotide binding	15/49(188)
27	GO:0000287	magnesium ion binding	3/49(188)
27	GO:0002039	p53 binding	1/49(188)
27	GO:0004674	protein serine/threonine kinase activity	1/49(188)
27	GO:0004672	protein kinase activity	5/49(188)
20	GO:0004222	metalloendopeptidase activity	4/60(240)
20	GO:0005524	ATP binding	11/60(240)
20	GO:0000166	nucleotide binding	26/60(240)
21	GO:0001221	transcription cofactor binding	1/62(240)
21	GO:0001046	core promoter sequence-specific DNA binding	2/62(240)
21	GO:0000166	nucleotide binding	1/62(240)
21	GO:0001105	RNA polymerase II transcription coactivator activity	2/62(240)
21	GO:0003676	nucleic acid binding	5/62(240)
21	GO:0003677	DNA binding	6/62(240)
21	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/62(240)
21	GO:0003682	chromatin binding	3/62(240)
21	GO:0005524	ATP binding	12/62(240)
22	GO:0005216	ion channel activity	31/52(233)
28	GO:0048675	axon extension	2/39(187)
28	GO:0002292	T cell differentiation involved in immune response	1/39(187)
28	GO:0070062	extracellular exosome	1/39(187)
28	GO:0016020	membrane	4/39(187)
28	GO:0004888	transmembrane signaling receptor activity	2/39(187)
28	GO:0004872	receptor activity	1/39(187)
28	GO:0005886	plasma membrane	2/39(187)
28	GO:0001843	neural tube closure	1/39(187)
28	GO:0030215	semaphorin receptor binding	6/39(187)
3790	GO:0005794	Golgi apparatus	2/3(9)
2154	GO:0008199	ferric iron binding	1/3(14)
2154	GO:0005506	iron ion binding	2/3(14)
2407	GO:0016020	membrane	1/3(11)
2407	GO:0003682	chromatin binding	1/3(11)
939	GO:0015349	thyroid hormone transmembrane transporter activity	1/5(22)
939	GO:0015173	aromatic amino acid transmembrane transporter activity	2/5(22)
938	GO:0003677	DNA binding	1/5(22)
402	GO:0004872	receptor activity	1/5(33)
2152	GO:0003676	nucleic acid binding	1/3(14)
931	GO:0015278	calcium-release channel activity	1/6(22)
931	GO:0005096	GTPase activator activity	3/6(22)
930	GO:0004888	transmembrane signaling receptor activity	2/5(22)
9063	GO:0004017	adenylate kinase activity	1/1(6)
2746	GO:0007009	plasma membrane organization	1/3(10)
2746	GO:0005543	phospholipid binding	1/3(10)
3566	GO:0008307	structural constituent of muscle	1/3(9)
2283	GO:0003676	nucleic acid binding	3/3(13)
3243	GO:0016791	phosphatase activity	1/3(9)
3243	GO:0004721	phosphoprotein phosphatase activity	1/3(9)
2319	GO:0016020	membrane	2/3(12)
828	GO:0004871	signal transducer activity	5/5(23)
1063	GO:0007010	cytoskeleton organization	1/6(19)
376	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1/8(33)
2902	GO:0031625	ubiquitin protein ligase binding	2/3(9)
708	GO:0008017	microtubule binding	3/5(24)
708	GO:0005622	intracellular	1/5(24)
147	GO:0019901	protein kinase binding	1/12(61)
147	GO:0016020	membrane	3/12(61)
147	GO:0030220	platelet formation	1/12(61)
705	GO:0005085	guanyl-nucleotide exchange factor activity	1/6(25)
393	GO:0016020	membrane	1/8(33)
1484	GO:0000287	magnesium ion binding	1/5(17)
82	GO:0000166	nucleotide binding	14/25(101)
80	GO:0005215	transporter activity	7/26(103)
1066	GO:0003735	structural constituent of ribosome	1/3(19)
1066	GO:0006396	RNA processing	1/3(19)
86	GO:0003824	catalytic activity	2/27(97)
86	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	13/27(97)
85	GO:0004866	endopeptidase inhibitor activity	13/25(99)
796	GO:0005509	calcium ion binding	1/6(24)
2410	GO:0003729	mRNA binding	1/3(11)
2301	GO:0016020	membrane	2/5(13)
7	GO:0000166	nucleotide binding	21/107(435)
7	GO:0000287	magnesium ion binding	5/107(435)
7	GO:0004672	protein kinase activity	29/107(435)
5840	GO:0001968	fibronectin binding	2/3(8)
3665	GO:0016176	superoxide-generating NADPH oxidase activator activity	2/3(9)
8755	GO:0003735	structural constituent of ribosome	1/1(6)
413	GO:0003779	actin binding	2/7(32)
1137	GO:0002062	chondrocyte differentiation	1/5(18)
1137	GO:0016020	membrane	3/5(18)
2286	GO:0008134	transcription factor binding	2/3(13)
589	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	4/7(27)
244	GO:0008233	peptidase activity	4/10(44)
244	GO:0001968	fibronectin binding	1/10(44)
246	GO:0008270	zinc ion binding	2/8(44)
240	GO:0000166	nucleotide binding	5/9(44)
243	GO:0005509	calcium ion binding	1/9(44)
243	GO:0019899	enzyme binding	1/9(44)
243	GO:0002175	protein localization to paranode region of axon	1/9(44)
242	GO:0003677	DNA binding	2/8(44)
242	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/8(44)
242	GO:0001046	core promoter sequence-specific DNA binding	2/8(44)
249	GO:0000175	3'-5'-exoribonuclease activity	1/9(43)
7781	GO:0008089	anterograde axonal transport	1/1(7)
1432	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/3(17)
2579	GO:0003950	NAD+ ADP-ribosyltransferase activity	1/4(10)
2574	GO:0008168	methyltransferase activity	1/2(10)
1438	GO:0016020	membrane	1/5(17)
1438	GO:0007601	visual perception	1/5(17)
1007	GO:0004077	biotin-[acetyl-CoA-carboxylase] ligase activity	3/3(20)
1006	GO:0001933	negative regulation of protein phosphorylation	1/6(20)
512	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/6(29)
515	GO:0005856	cytoskeleton	1/6(29)
515	GO:0030674	protein binding, bridging	1/6(29)
515	GO:0090162	establishment of epithelial cell polarity	1/6(29)
514	GO:0019901	protein kinase binding	2/6(29)
517	GO:0003779	actin binding	1/9(29)
459	GO:0008017	microtubule binding	3/7(31)
459	GO:0003723	RNA binding	1/7(31)
620	GO:0000976	transcription regulatory region sequence-specific DNA binding	2/7(26)
620	GO:0030259	lipid glycosylation	1/7(26)
620	GO:0000989	transcription factor activity, transcription factor binding	2/7(26)
627	GO:0003824	catalytic activity	6/7(25)
10658	GO:0004045	aminoacyl-tRNA hydrolase activity	1/1(2)
625	GO:0005506	iron ion binding	1/6(26)
625	GO:0004051	arachidonate 5-lipoxygenase activity	1/6(26)
1220	GO:0003676	nucleic acid binding	2/8(18)
2455	GO:0004348	glucosylceramidase activity	3/4(11)
1343	GO:0005114	type II transforming growth factor beta receptor binding	2/5(17)
1343	GO:0001540	beta-amyloid binding	2/5(17)
454	GO:0005198	structural molecule activity	5/7(31)
179	GO:0000166	nucleotide binding	5/10(55)
176	GO:0016787	hydrolase activity	4/12(56)
176	GO:0008017	microtubule binding	4/12(56)
176	GO:0004157	dihydropyrimidinase activity	2/12(56)
7917	GO:0003677	DNA binding	1/1(7)
172	GO:0001964	startle response	2/16(56)
172	GO:0007409	axonogenesis	4/16(56)
172	GO:0051965	positive regulation of synapse assembly	2/16(56)
172	GO:0007399	nervous system development	2/16(56)
975	GO:0000166	nucleotide binding	4/7(21)
973	GO:0004622	lysophospholipase activity	1/6(21)
7714	GO:0004181	metallocarboxypeptidase activity	1/1(7)
2056	GO:0035556	intracellular signal transduction	2/3(15)
3696	GO:0055085	transmembrane transport	1/3(9)
978	GO:0016407	acetyltransferase activity	2/5(21)
978	GO:0004596	peptide alpha-N-acetyltransferase activity	1/5(21)
182	GO:0010811	positive regulation of cell-substrate adhesion	2/12(55)
182	GO:0005102	receptor binding	1/12(55)
182	GO:0008157	protein phosphatase 1 binding	2/12(55)
182	GO:0005176	ErbB-2 class receptor binding	1/12(55)
183	GO:0044822	poly(A) RNA binding	2/15(55)
183	GO:0007601	visual perception	2/15(55)
183	GO:0005212	structural constituent of eye lens	4/15(55)
183	GO:0042803	protein homodimerization activity	1/15(55)
180	GO:0005096	GTPase activator activity	2/14(55)
180	GO:0005509	calcium ion binding	2/14(55)
2	GO:0000166	nucleotide binding	33/155(642)
2	GO:0003924	GTPase activity	35/155(642)
2	GO:0005509	calcium ion binding	2/155(642)
2	GO:0005525	GTP binding	32/155(642)
186	GO:0005216	ion channel activity	11/13(52)
187	GO:0005201	extracellular matrix structural constituent	2/12(52)
184	GO:0000226	microtubule cytoskeleton organization	1/6(55)
7987	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	1/1(7)
188	GO:0001664	G-protein coupled receptor binding	3/12(51)
188	GO:0004871	signal transducer activity	6/12(51)
189	GO:0004407	histone deacetylase activity	1/8(51)
189	GO:0001025	RNA polymerase III transcription factor binding	1/8(51)
8377	GO:0004129	cytochrome-c oxidase activity	1/1(7)
9405	GO:0035612	AP-2 adaptor complex binding	1/3(5)
8576	GO:0030514	negative regulation of BMP signaling pathway	1/1(6)
9239	GO:0004175	endopeptidase activity	1/1(5)
3283	GO:0004842	ubiquitin-protein transferase activity	2/3(9)
11	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9/99(347)
11	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/99(347)
11	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/99(347)
11	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	3/99(347)
11	GO:0003677	DNA binding	30/99(347)
10	GO:0005509	calcium ion binding	34/114(380)
13	GO:0004984	olfactory receptor activity	3/94(336)
13	GO:0004871	signal transducer activity	31/94(336)
13	GO:0003707	steroid hormone receptor activity	1/94(336)
12	GO:0004930	G-protein coupled receptor activity	6/93(341)
12	GO:0004871	signal transducer activity	51/93(341)
12	GO:0001626	nociceptin receptor activity	2/93(341)
12	GO:0001596	angiotensin type I receptor activity	2/93(341)
12	GO:0003779	actin binding	2/93(341)
12	GO:0001965	G-protein alpha-subunit binding	1/93(341)
12	GO:0002020	protease binding	2/93(341)
15	GO:0004725	protein tyrosine phosphatase activity	7/74(303)
15	GO:0008134	transcription factor binding	1/74(303)
15	GO:0004721	phosphoprotein phosphatase activity	27/74(303)
15	GO:0001784	phosphotyrosine binding	4/74(303)
15	GO:0003712	transcription cofactor activity	1/74(303)
14	GO:0003777	microtubule motor activity	1/81(313)
14	GO:0000166	nucleotide binding	38/81(313)
17	GO:0004672	protein kinase activity	7/57(257)
17	GO:0002039	p53 binding	1/57(257)
17	GO:0000166	nucleotide binding	22/57(257)
16	GO:0003676	nucleic acid binding	14/69(264)
16	GO:0000166	nucleotide binding	25/69(264)
19	GO:0004890	GABA-A receptor activity	24/58(244)
19	GO:0005230	extracellular ligand-gated ion channel activity	10/58(244)
19	GO:0006811	ion transport	1/58(244)
18	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	2/66(256)
18	GO:0004930	G-protein coupled receptor activity	1/66(256)
18	GO:0001594	trace-amine receptor activity	1/66(256)
18	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	4/66(256)
18	GO:0001587	Gq/11-coupled serotonin receptor activity	2/66(256)
18	GO:0001965	G-protein alpha-subunit binding	2/66(256)
18	GO:0004871	signal transducer activity	28/66(256)
863	GO:0000166	nucleotide binding	4/6(23)
862	GO:0005215	transporter activity	4/5(23)
3889	GO:0045600	positive regulation of fat cell differentiation	1/3(9)
866	GO:0003858	3-hydroxybutyrate dehydrogenase activity	2/6(23)
3679	GO:0005509	calcium ion binding	1/3(9)
2020	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/3(15)
2020	GO:0003677	DNA binding	1/3(15)
2083	GO:0042803	protein homodimerization activity	1/3(14)
2696	GO:0003700	transcription factor activity, sequence-specific DNA binding	2/4(10)
883	GO:0030534	adult behavior	1/4(23)
882	GO:0000166	nucleotide binding	2/5(23)
2086	GO:0003676	nucleic acid binding	3/3(14)
940	GO:0004871	signal transducer activity	3/11(22)
7641	GO:0003676	nucleic acid binding	1/1(7)
2017	GO:0008233	peptidase activity	1/4(15)
5195	GO:0003940	L-iduronidase activity	1/2(8)
1966	GO:0008190	eukaryotic initiation factor 4E binding	2/3(15)
320	GO:0032403	protein complex binding	2/9(37)
320	GO:0051020	GTPase binding	2/9(37)
320	GO:0003924	GTPase activity	1/9(37)
320	GO:0007165	signal transduction	1/9(37)
321	GO:0017112	Rab guanyl-nucleotide exchange factor activity	4/9(37)
325	GO:0008277	regulation of G-protein coupled receptor protein signaling pathway	3/9(36)
200	GO:0016020	membrane	2/10(50)
203	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/14(49)
203	GO:0000976	transcription regulatory region sequence-specific DNA binding	3/14(49)
203	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	1/14(49)
203	GO:0006366	transcription from RNA polymerase II promoter	1/14(49)
202	GO:0005509	calcium ion binding	8/11(50)
204	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/11(49)
204	GO:0046983	protein dimerization activity	4/11(49)
206	GO:0006355	regulation of transcription, DNA-templated	1/10(49)
206	GO:0001106	RNA polymerase II transcription corepressor activity	1/10(49)
206	GO:0003682	chromatin binding	1/10(49)
77	GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/26(103)
77	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	1/26(103)
77	GO:0000166	nucleotide binding	20/26(103)
76	GO:0001948	glycoprotein binding	1/22(105)
76	GO:0005576	extracellular region	1/22(105)
76	GO:0001657	ureteric bud development	2/22(105)
75	GO:0005179	hormone activity	2/25(107)
75	GO:0005125	cytokine activity	2/25(107)
75	GO:0004745	retinol dehydrogenase activity	1/25(107)
75	GO:0008083	growth factor activity	11/25(107)
74	GO:0004872	receptor activity	12/27(108)
74	GO:0004970	ionotropic glutamate receptor activity	3/27(108)
72	GO:0004252	serine-type endopeptidase activity	2/25(108)
72	GO:0016020	membrane	1/25(108)
72	GO:0005044	scavenger receptor activity	1/25(108)
71	GO:0001601	peptide YY receptor activity	7/30(108)
71	GO:0004930	G-protein coupled receptor activity	2/30(108)
71	GO:0004871	signal transducer activity	14/30(108)
78	GO:0005216	ion channel activity	2/14(103)
78	GO:0005245	voltage-gated calcium channel activity	1/14(103)
2336	GO:0003712	transcription cofactor activity	2/4(12)
2338	GO:0005524	ATP binding	1/3(12)
1049	GO:0005783	endoplasmic reticulum	2/4(20)
2234	GO:0004872	receptor activity	1/3(13)
2067	GO:0006336	DNA replication-independent nucleosome assembly	2/4(15)
8257	GO:0005525	GTP binding	1/1(7)
1141	GO:0005113	patched binding	2/5(18)
1141	GO:0005119	smoothened binding	1/5(18)
3498	GO:0004672	protein kinase activity	1/3(9)
666	GO:0005215	transporter activity	6/7(25)
1148	GO:0044822	poly(A) RNA binding	1/3(18)
1149	GO:0007281	germ cell development	1/5(18)
1149	GO:0044822	poly(A) RNA binding	1/5(18)
663	GO:0000166	nucleotide binding	2/7(25)
1266	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	2/5(17)
1266	GO:0005154	epidermal growth factor receptor binding	2/5(17)
2096	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/3(14)
2096	GO:0003677	DNA binding	1/3(14)
2090	GO:0003684	damaged DNA binding	2/3(14)
2093	GO:0005096	GTPase activator activity	2/3(14)
693	GO:0008134	transcription factor binding	1/7(25)
2527	GO:0003682	chromatin binding	1/3(11)
1540	GO:0005319	lipid transporter activity	2/5(16)
3124	GO:0004843	thiol-dependent ubiquitin-specific protease activity	2/3(9)
1279	GO:0000185	activation of MAPKKK activity	1/3(17)
541	GO:0009966	regulation of signal transduction	1/7(28)
541	GO:0005634	nucleus	1/7(28)
2248	GO:0016020	membrane	1/3(13)
8	GO:0003774	motor activity	3/108(417)
8	GO:0007165	signal transduction	1/108(417)
8	GO:0000146	microfilament motor activity	8/108(417)
8	GO:0000166	nucleotide binding	38/108(417)
2246	GO:0005179	hormone activity	1/3(13)
1466	GO:0034613	cellular protein localization	1/5(17)
2241	GO:0016787	hydrolase activity	1/3(13)
869	GO:0043237	laminin-1 binding	2/7(23)
869	GO:0005576	extracellular region	2/7(23)
523	GO:0005102	receptor binding	2/6(28)
1319	GO:0001223	transcription coactivator binding	1/5(17)
1319	GO:0003677	DNA binding	2/5(17)
1318	GO:0005524	ATP binding	1/5(17)
120	GO:0004252	serine-type endopeptidase activity	2/14(75)
120	GO:0004175	endopeptidase activity	4/14(75)
120	GO:0002020	protease binding	1/14(75)
124	GO:0000166	nucleotide binding	12/14(73)
126	GO:0008146	sulfotransferase activity	11/19(71)
128	GO:0005543	phospholipid binding	1/12(70)
128	GO:0016021	integral component of membrane	1/12(70)
128	GO:0016020	membrane	2/12(70)
3881	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	2/3(9)
3883	GO:0016020	membrane	3/3(9)
132	GO:0004721	phosphoprotein phosphatase activity	8/14(68)
2068	GO:0016020	membrane	1/6(15)
2068	GO:0001764	neuron migration	1/6(15)
929	GO:0019905	syntaxin binding	1/5(22)
929	GO:0010468	regulation of gene expression	1/5(22)
2145	GO:0004672	protein kinase activity	1/3(14)
2142	GO:0031870	thromboxane A2 receptor binding	1/3(14)
2416	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/3(11)
922	GO:0004478	methionine adenosyltransferase activity	1/5(22)
922	GO:0000166	nucleotide binding	2/5(22)
923	GO:0007286	spermatid development	1/5(22)
923	GO:0002151	G-quadruplex RNA binding	1/5(22)
7724	GO:0006412	translation	1/2(7)
7724	GO:0003723	RNA binding	1/2(7)
7726	GO:0005634	nucleus	1/1(7)
927	GO:0003824	catalytic activity	4/5(22)
319	GO:0003824	catalytic activity	5/9(37)
135	GO:0000155	phosphorelay sensor kinase activity	3/15(65)
135	GO:0005216	ion channel activity	1/15(65)
3821	GO:0016740	transferase activity	2/3(9)
312	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity	2/10(37)
310	GO:0006351	transcription, DNA-templated	1/7(37)
310	GO:0003677	DNA binding	2/7(37)
317	GO:0043410	positive regulation of MAPK cascade	2/7(37)
317	GO:0016462	pyrophosphatase activity	1/7(37)
317	GO:0019894	kinesin binding	2/7(37)
314	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/10(37)
314	GO:0003676	nucleic acid binding	5/10(37)
3277	GO:0009607	response to biotic stimulus	1/3(9)
8043	GO:0001933	negative regulation of protein phosphorylation	1/1(7)
9656	GO:0003735	structural constituent of ribosome	2/2(4)
1927	GO:0004129	cytochrome-c oxidase activity	1/4(15)
9714	GO:0005525	GTP binding	1/1(4)
830	GO:0046983	protein dimerization activity	1/6(23)
830	GO:0004842	ubiquitin-protein transferase activity	3/6(23)
4128	GO:0003677	DNA binding	1/1(8)
4127	GO:0005739	mitochondrion	2/2(8)
2763	GO:0007275	multicellular organism development	1/3(10)
3	GO:0000287	magnesium ion binding	1/139(535)
3	GO:0000166	nucleotide binding	72/139(535)
3	GO:0003779	actin binding	2/139(535)
3	GO:0004713	protein tyrosine kinase activity	1/139(535)
3	GO:0004672	protein kinase activity	11/139(535)
3	GO:0005524	ATP binding	1/139(535)
2755	GO:0016020	membrane	1/3(10)
369	GO:0008198	ferrous iron binding	1/6(34)
381	GO:0000166	nucleotide binding	2/5(33)
383	GO:0003677	DNA binding	9/11(33)
385	GO:0004672	protein kinase activity	1/5(33)
385	GO:0000166	nucleotide binding	4/5(33)
389	GO:0005158	insulin receptor binding	1/9(33)
389	GO:0006357	regulation of transcription from RNA polymerase II promoter	1/9(33)
7029	GO:0003677	DNA binding	1/1(8)
784	GO:0005509	calcium ion binding	3/6(24)
788	GO:0004672	protein kinase activity	1/6(24)
788	GO:0000166	nucleotide binding	1/6(24)
9004	GO:0005739	mitochondrion	1/1(6)
3758	GO:0003723	RNA binding	1/3(9)
579	GO:0019899	enzyme binding	2/7(27)
578	GO:0005102	receptor binding	2/7(27)
572	GO:0004672	protein kinase activity	2/5(27)
3753	GO:0044822	poly(A) RNA binding	1/3(9)
576	GO:0004725	protein tyrosine phosphatase activity	1/5(27)
29	GO:0001756	somitogenesis	1/44(182)
29	GO:0035064	methylated histone binding	2/44(182)
29	GO:0030332	cyclin binding	1/44(182)
29	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/44(182)
29	GO:0008017	microtubule binding	4/44(182)
29	GO:0003713	transcription coactivator activity	2/44(182)
29	GO:0003431	growth plate cartilage chondrocyte development	1/44(182)
29	GO:0005198	structural molecule activity	2/44(182)
29	GO:0006364	rRNA processing	1/44(182)
29	GO:0019904	protein domain specific binding	3/44(182)
29	GO:0008168	methyltransferase activity	1/44(182)
29	GO:0001895	retina homeostasis	1/44(182)
29	GO:0004842	ubiquitin-protein transferase activity	3/44(182)
29	GO:0044822	poly(A) RNA binding	1/44(182)
29	GO:0008270	zinc ion binding	2/44(182)
61	GO:0008284	positive regulation of cell proliferation	1/24(119)
61	GO:0005102	receptor binding	4/24(119)
61	GO:0000904	cell morphogenesis involved in differentiation	1/24(119)
61	GO:0001764	neuron migration	1/24(119)
61	GO:0005201	extracellular matrix structural constituent	1/24(119)
63	GO:0001641	group II metabotropic glutamate receptor activity	4/24(116)
63	GO:0004871	signal transducer activity	8/24(116)
65	GO:0016020	membrane	1/24(116)
65	GO:0004222	metalloendopeptidase activity	5/24(116)
65	GO:0004872	receptor activity	2/24(116)
65	GO:0005518	collagen binding	1/24(116)
65	GO:0005509	calcium ion binding	2/24(116)
67	GO:0005216	ion channel activity	7/22(112)
252	GO:0019992	diacylglycerol binding	4/7(42)
252	GO:0030742	GTP-dependent protein binding	1/7(42)
69	GO:0003779	actin binding	5/25(109)
69	GO:0003725	double-stranded RNA binding	1/25(109)
69	GO:0005509	calcium ion binding	3/25(109)
2800	GO:0033566	gamma-tubulin complex localization	1/3(9)
3313	GO:0019894	kinesin binding	2/3(9)
600	GO:0005169	neurotrophin TRKB receptor binding	1/7(26)
600	GO:0046875	ephrin receptor binding	2/7(26)
2569	GO:0016020	membrane	2/3(10)
1588	GO:0004842	ubiquitin-protein transferase activity	2/5(16)
1588	GO:0001662	behavioral fear response	2/5(16)
3368	GO:0003677	DNA binding	2/3(9)
406	GO:0002244	hematopoietic progenitor cell differentiation	2/8(33)
406	GO:0006367	transcription initiation from RNA polymerase II promoter	1/8(33)
406	GO:0003677	DNA binding	1/8(33)
1373	GO:0005154	epidermal growth factor receptor binding	1/4(17)
1038	GO:0030041	actin filament polymerization	1/4(20)
2157	GO:0000149	SNARE binding	2/3(14)
508	GO:0019208	phosphatase regulator activity	1/5(29)
508	GO:0017112	Rab guanyl-nucleotide exchange factor activity	2/5(29)
1032	GO:0046872	metal ion binding	3/5(20)
1032	GO:0005545	1-phosphatidylinositol binding	1/5(20)
1030	GO:0044822	poly(A) RNA binding	2/6(20)
1030	GO:0016020	membrane	2/6(20)
503	GO:0003677	DNA binding	2/6(29)
1034	GO:0005543	phospholipid binding	1/5(20)
1034	GO:0005096	GTPase activator activity	1/5(20)
501	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/9(29)
501	GO:0003677	DNA binding	6/9(29)
469	GO:0003676	nucleic acid binding	2/7(30)
637	GO:0004888	transmembrane signaling receptor activity	4/9(25)
637	GO:0005149	interleukin-1 receptor binding	2/9(25)
637	GO:0019843	rRNA binding	1/9(25)
465	GO:0006355	regulation of transcription, DNA-templated	1/10(31)
465	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/10(31)
465	GO:0003677	DNA binding	1/10(31)
464	GO:0004656	procollagen-proline 4-dioxygenase activity	4/7(31)
467	GO:0044822	poly(A) RNA binding	1/7(31)
467	GO:0016020	membrane	3/7(31)
38	GO:0070062	extracellular exosome	3/36(156)
38	GO:0005102	receptor binding	7/36(156)
38	GO:0003735	structural constituent of ribosome	1/36(156)
38	GO:0008061	chitin binding	1/36(156)
38	GO:0008233	peptidase activity	2/36(156)
38	GO:0004857	enzyme inhibitor activity	1/36(156)
164	GO:0016020	membrane	3/13(57)
165	GO:0003677	DNA binding	20/24(57)
309	GO:0016020	membrane	1/7(38)
309	GO:0005086	ARF guanyl-nucleotide exchange factor activity	2/7(38)
7846	GO:0030318	melanocyte differentiation	1/1(7)
161	GO:0003824	catalytic activity	1/10(57)
161	GO:0007165	signal transduction	1/10(57)
161	GO:0042803	protein homodimerization activity	2/10(57)
163	GO:0004177	aminopeptidase activity	3/12(57)
163	GO:0008237	metallopeptidase activity	3/12(57)
163	GO:0006508	proteolysis	1/12(57)
961	GO:0006479	protein methylation	1/5(21)
961	GO:0019899	enzyme binding	1/5(21)
963	GO:0003690	double-stranded DNA binding	2/5(21)
963	GO:0003677	DNA binding	1/5(21)
3683	GO:0044822	poly(A) RNA binding	1/3(9)
3687	GO:0003676	nucleic acid binding	1/3(9)
2890	GO:0016020	membrane	2/3(9)
1106	GO:0000166	nucleotide binding	3/5(19)
1457	GO:0003723	RNA binding	2/5(17)
1100	GO:0003824	catalytic activity	2/5(19)
2100	GO:0006364	rRNA processing	2/8(14)
2100	GO:0016491	oxidoreductase activity	2/8(14)
1510	GO:0000900	translation repressor activity, nucleic acid binding	1/3(16)
1109	GO:0003779	actin binding	3/6(19)
9342	GO:0001601	peptide YY receptor activity	2/3(5)
30	GO:0017147	Wnt-protein binding	1/37(182)
30	GO:0001540	beta-amyloid binding	1/37(182)
30	GO:0005041	low-density lipoprotein receptor activity	2/37(182)
30	GO:0005509	calcium ion binding	6/37(182)
30	GO:0001948	glycoprotein binding	1/37(182)
2639	GO:0016020	membrane	1/3(10)
8367	GO:0004129	cytochrome-c oxidase activity	1/1(7)
2635	GO:0003840	gamma-glutamyltransferase activity	3/3(10)
3865	GO:0001104	RNA polymerase II transcription cofactor activity	2/3(9)
8560	GO:0003677	DNA binding	1/1(6)
9595	GO:0016020	membrane	1/1(4)
1818	GO:0016020	membrane	3/5(16)
871	GO:0017112	Rab guanyl-nucleotide exchange factor activity	2/5(23)
2033	GO:0006810	transport	2/3(15)
2030	GO:0016301	kinase activity	3/4(15)
9	GO:0007626	locomotory behavior	1/100(386)
9	GO:0000070	mitotic sister chromatid segregation	1/100(386)
9	GO:0000902	cell morphogenesis	2/100(386)
9	GO:0005783	endoplasmic reticulum	1/100(386)
9	GO:0006355	regulation of transcription, DNA-templated	2/100(386)
9	GO:0002467	germinal center formation	2/100(386)
9	GO:0051015	actin filament binding	1/100(386)
9	GO:0003779	actin binding	6/100(386)
9	GO:0016567	protein ubiquitination	8/100(386)
9	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	1/100(386)
9	GO:0007010	cytoskeleton organization	1/100(386)
9	GO:0031397	negative regulation of protein ubiquitination	2/100(386)
9	GO:2000312	regulation of kainate selective glutamate receptor activity	2/100(386)
9	GO:0004842	ubiquitin-protein transferase activity	4/100(386)
9	GO:0006446	regulation of translational initiation	3/100(386)
9	GO:0042802	identical protein binding	3/100(386)
9	GO:0005615	extracellular space	2/100(386)
890	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2/6(22)
895	GO:0003677	DNA binding	1/9(22)
5204	GO:0016020	membrane	1/1(8)
1975	GO:0008083	growth factor activity	2/3(15)
3548	GO:0004869	cysteine-type endopeptidase inhibitor activity	1/3(9)
3220	GO:0042974	retinoic acid receptor binding	1/3(9)
355	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/7(34)
355	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/7(34)
355	GO:0003676	nucleic acid binding	1/7(34)
351	GO:0070062	extracellular exosome	2/5(34)
805	GO:0006810	transport	1/6(24)
804	GO:0004672	protein kinase activity	3/7(24)
214	GO:0005654	nucleoplasm	2/13(48)
214	GO:0016020	membrane	4/13(48)
214	GO:0007601	visual perception	2/13(48)
214	GO:0051965	positive regulation of synapse assembly	2/13(48)
212	GO:0005216	ion channel activity	4/7(49)
213	GO:0010811	positive regulation of cell-substrate adhesion	1/13(48)
213	GO:0005102	receptor binding	1/13(48)
213	GO:0005576	extracellular region	4/13(48)
213	GO:0042802	identical protein binding	2/13(48)
219	GO:0000166	nucleotide binding	7/10(48)
3103	GO:0003677	DNA binding	2/3(9)
1079	GO:0030544	Hsp70 protein binding	2/4(19)
2329	GO:0043066	negative regulation of apoptotic process	2/3(12)
4	GO:0001948	glycoprotein binding	1/119(497)
4	GO:0004252	serine-type endopeptidase activity	50/119(497)
4	GO:0004175	endopeptidase activity	2/119(497)
283	GO:0006810	transport	3/10(40)
283	GO:0015485	cholesterol binding	3/10(40)
284	GO:0007270	neuron-neuron synaptic transmission	2/9(40)
284	GO:0001540	beta-amyloid binding	1/9(40)
1095	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/4(19)
1090	GO:0019903	protein phosphatase binding	2/6(19)
1090	GO:0006810	transport	2/6(19)
1091	GO:0003677	DNA binding	2/5(19)
1093	GO:0001158	enhancer sequence-specific DNA binding	1/4(19)
675	GO:0008106	alcohol dehydrogenase (NADP+) activity	1/7(25)
676	GO:0000166	nucleotide binding	3/7(25)
262	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/11(42)
262	GO:0001076	transcription factor activity, RNA polymerase II transcription factor binding	2/11(42)
262	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/11(42)
262	GO:0000976	transcription regulatory region sequence-specific DNA binding	2/11(42)
262	GO:0001158	enhancer sequence-specific DNA binding	1/11(42)
265	GO:0000166	nucleotide binding	3/11(42)
3132	GO:0008599	protein phosphatase type 1 regulator activity	2/3(9)
118	GO:0016301	kinase activity	8/20(77)
118	GO:0046854	phosphatidylinositol phosphorylation	1/20(77)
118	GO:0000166	nucleotide binding	2/20(77)
2551	GO:0003735	structural constituent of ribosome	2/9(11)
2551	GO:0005737	cytoplasm	1/9(11)
59	GO:0004889	acetylcholine-activated cation-selective channel activity	21/31(122)
55	GO:0001948	glycoprotein binding	1/29(130)
55	GO:0001764	neuron migration	1/29(130)
55	GO:0002020	protease binding	2/29(130)
55	GO:0007155	cell adhesion	4/29(130)
55	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	1/29(130)
55	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/29(130)
55	GO:0005112	Notch binding	2/29(130)
55	GO:0030506	ankyrin binding	2/29(130)
54	GO:0000166	nucleotide binding	20/33(131)
57	GO:0000166	nucleotide binding	21/30(129)
56	GO:0004888	transmembrane signaling receptor activity	2/34(130)
56	GO:0004871	signal transducer activity	20/34(130)
51	GO:0048306	calcium-dependent protein binding	2/31(135)
51	GO:0000149	SNARE binding	3/31(135)
51	GO:0006887	exocytosis	1/31(135)
51	GO:0005544	calcium-dependent phospholipid binding	2/31(135)
51	GO:0017158	regulation of calcium ion-dependent exocytosis	1/31(135)
51	GO:0005509	calcium ion binding	4/31(135)
51	GO:0001786	phosphatidylserine binding	1/31(135)
51	GO:0017156	calcium ion regulated exocytosis	1/31(135)
50	GO:0055077	gap junction hemi-channel activity	2/43(137)
50	GO:0001568	blood vessel development	1/43(137)
50	GO:0001508	action potential	1/43(137)
50	GO:0004871	signal transducer activity	2/43(137)
50	GO:0002088	lens development in camera-type eye	1/43(137)
50	GO:0007154	cell communication	12/43(137)
50	GO:0005243	gap junction channel activity	4/43(137)
50	GO:0005216	ion channel activity	2/43(137)
50	GO:0042803	protein homodimerization activity	2/43(137)
53	GO:0000975	regulatory region DNA binding	1/39(133)
53	GO:0001972	retinoic acid binding	1/39(133)
53	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/39(133)
53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	6/39(133)
53	GO:0001046	core promoter sequence-specific DNA binding	2/39(133)
53	GO:0003677	DNA binding	9/39(133)
53	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	4/39(133)
53	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3/39(133)
52	GO:0005242	inward rectifier potassium channel activity	21/35(134)
2397	GO:0048306	calcium-dependent protein binding	1/5(12)
533	GO:0005086	ARF guanyl-nucleotide exchange factor activity	6/7(28)
2259	GO:0019899	enzyme binding	1/3(13)
1413	GO:0046872	metal ion binding	3/5(17)
8052	GO:0003677	DNA binding	1/1(7)
3144	GO:0045892	negative regulation of transcription, DNA-templated	2/3(9)
1320	GO:0003676	nucleic acid binding	3/5(17)
1321	GO:0019901	protein kinase binding	2/5(17)
1328	GO:0006469	negative regulation of protein kinase activity	2/5(17)
2775	GO:0004064	arylesterase activity	1/3(10)
2777	GO:0004167	dopachrome isomerase activity	1/3(10)
115	GO:0005102	receptor binding	11/20(79)
5604	GO:0035556	intracellular signal transduction	1/3(8)
116	GO:0017154	semaphorin receptor activity	7/21(78)
3295	GO:0004476	mannose-6-phosphate isomerase activity	2/3(9)
2997	GO:0003723	RNA binding	1/3(9)
250	GO:0004871	signal transducer activity	1/11(43)
428	GO:0004725	protein tyrosine phosphatase activity	1/7(32)
428	GO:0000975	regulatory region DNA binding	4/7(32)
2170	GO:0003677	DNA binding	1/3(14)
919	GO:0000287	magnesium ion binding	4/5(22)
2073	GO:0005737	cytoplasm	1/3(14)
420	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/10(32)
4963	GO:0016020	membrane	2/3(8)
2076	GO:0003713	transcription coactivator activity	1/3(14)
913	GO:0008195	phosphatidate phosphatase activity	3/5(22)
308	GO:0005654	nucleoplasm	2/9(38)
308	GO:0008270	zinc ion binding	1/9(38)
3813	GO:0000266	mitochondrial fission	1/2(9)
3810	GO:0000166	nucleotide binding	2/3(9)
2600	GO:0005521	lamin binding	1/3(10)
2602	GO:0003676	nucleic acid binding	1/3(10)
2602	GO:0002151	G-quadruplex RNA binding	1/3(10)
300	GO:0008092	cytoskeletal protein binding	1/7(38)
3818	GO:0005737	cytoplasm	1/3(9)
303	GO:0003824	catalytic activity	7/9(38)
304	GO:0016787	hydrolase activity	5/17(38)
305	GO:0015020	glucuronosyltransferase activity	1/17(38)
306	GO:0000166	nucleotide binding	4/9(38)
10035	GO:0008270	zinc ion binding	1/1(3)
3466	GO:0009607	response to biotic stimulus	1/3(9)
843	GO:0015026	coreceptor activity	2/5(23)
843	GO:0042802	identical protein binding	1/5(23)
8950	GO:0050995	negative regulation of lipid catabolic process	1/1(6)
2677	GO:0042981	regulation of apoptotic process	1/3(10)
2677	GO:0004672	protein kinase activity	1/3(10)
822	GO:0007165	signal transduction	1/5(23)
2661	GO:0042393	histone binding	1/3(10)
2474	GO:0005634	nucleus	1/3(11)
9035	GO:0005179	hormone activity	1/2(6)
424	GO:0045296	cadherin binding	2/9(32)
424	GO:0005198	structural molecule activity	4/9(32)
1982	GO:0000287	magnesium ion binding	1/3(15)
1983	GO:0008017	microtubule binding	1/3(15)
1983	GO:0004871	signal transducer activity	1/3(15)
3218	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/3(9)
1039	GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	3/5(20)
481	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	1/7(30)
481	GO:0004843	thiol-dependent ubiquitin-specific protease activity	1/7(30)
753	GO:0000166	nucleotide binding	1/5(24)
2181	GO:0003714	transcription corepressor activity	1/3(14)
2958	GO:0003697	single-stranded DNA binding	1/3(9)
3076	GO:0047485	protein N-terminus binding	2/3(9)
228	GO:0005085	guanyl-nucleotide exchange factor activity	9/12(47)
3079	GO:0004222	metalloendopeptidase activity	1/1(9)
2956	GO:0005524	ATP binding	2/3(9)
2188	GO:0003824	catalytic activity	1/3(14)
223	GO:0008233	peptidase activity	2/10(48)
223	GO:0004843	thiol-dependent ubiquitin-specific protease activity	2/10(48)
223	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	1/10(48)
222	GO:0005509	calcium ion binding	3/8(48)
221	GO:0004180	carboxypeptidase activity	9/14(48)
725	GO:0008270	zinc ion binding	4/6(24)
2353	GO:0030246	carbohydrate binding	1/3(12)
2350	GO:0016020	membrane	2/5(12)
155	GO:0003677	DNA binding	4/14(59)
1208	GO:0030198	extracellular matrix organization	1/6(18)
1208	GO:0005509	calcium ion binding	1/6(18)
157	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	4/13(58)
157	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/13(58)
157	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/13(58)
157	GO:0003677	DNA binding	2/13(58)
1163	GO:0008146	sulfotransferase activity	2/5(18)
159	GO:0000166	nucleotide binding	1/9(58)
112	GO:0003995	acyl-CoA dehydrogenase activity	11/19(82)
3736	GO:0000132	establishment of mitotic spindle orientation	1/3(9)
3734	GO:0008329	signaling pattern recognition receptor activity	2/3(9)
8272	GO:0016758	transferase activity, transferring hexosyl groups	1/1(7)
959	GO:0051297	centrosome organization	1/7(21)
959	GO:0016020	membrane	1/7(21)
2134	GO:0003682	chromatin binding	2/4(14)
81	GO:0003779	actin binding	1/27(102)
81	GO:0005856	cytoskeleton	4/27(102)
81	GO:0010592	positive regulation of lamellipodium assembly	1/27(102)
81	GO:0004721	phosphoprotein phosphatase activity	2/27(102)
81	GO:0008092	cytoskeletal protein binding	2/27(102)
2133	GO:1902979	mitotic DNA replication termination	3/3(14)
48	GO:0004842	ubiquitin-protein transferase activity	18/35(139)
48	GO:0003713	transcription coactivator activity	2/35(139)
49	GO:0003777	microtubule motor activity	11/30(138)
46	GO:0004435	phosphatidylinositol phospholipase C activity	14/34(146)
46	GO:0001786	phosphatidylserine binding	2/34(146)
47	GO:0001085	RNA polymerase II transcription factor binding	2/33(141)
47	GO:0000976	transcription regulatory region sequence-specific DNA binding	2/33(141)
47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	4/33(141)
47	GO:0003677	DNA binding	3/33(141)
47	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5/33(141)
47	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/33(141)
45	GO:0016740	transferase activity	11/36(147)
45	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	10/36(147)
42	GO:0005283	sodium:amino acid symporter activity	1/44(151)
42	GO:0005328	neurotransmitter:sodium symporter activity	31/44(151)
42	GO:0005298	proline:sodium symporter activity	2/44(151)
40	GO:0003924	GTPase activity	9/40(152)
40	GO:0004871	signal transducer activity	3/40(152)
40	GO:0005525	GTP binding	19/40(152)
41	GO:0000166	nucleotide binding	2/52(151)
41	GO:0004672	protein kinase activity	6/52(151)
1111	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/6(19)
1446	GO:0004767	sphingomyelin phosphodiesterase activity	1/5(17)
1446	GO:0008081	phosphoric diester hydrolase activity	2/5(17)
1298	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	1/5(17)
3194	GO:0035035	histone acetyltransferase binding	1/3(9)
5	GO:0000287	magnesium ion binding	2/130(478)
5	GO:0000166	nucleotide binding	70/130(478)
5	GO:0004674	protein serine/threonine kinase activity	1/130(478)
5	GO:0004672	protein kinase activity	10/130(478)
5	GO:0046872	metal ion binding	1/130(478)
5	GO:0002039	p53 binding	2/130(478)
1114	GO:0016020	membrane	2/12(19)
8674	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	1/1(6)
2500	GO:0003677	DNA binding	1/1(11)
2641	GO:0008270	zinc ion binding	1/3(10)
8392	GO:0003676	nucleic acid binding	1/1(7)
2647	GO:0035556	intracellular signal transduction	1/3(10)
2647	GO:0046872	metal ion binding	1/3(10)
488	GO:0032947	protein complex scaffold	3/8(30)
482	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	1/7(30)
482	GO:0004470	malic enzyme activity	5/7(30)
8002	GO:0000166	nucleotide binding	1/1(7)
8003	GO:0006904	vesicle docking involved in exocytosis	1/1(7)
3429	GO:0003960	NADPH:quinone reductase activity	2/3(9)
1802	GO:0045502	dynein binding	1/3(16)
3423	GO:0044822	poly(A) RNA binding	1/3(9)
472	GO:0003824	catalytic activity	6/7(30)
2000	GO:0003677	DNA binding	1/3(15)
471	GO:0005615	extracellular space	2/8(30)
471	GO:0001968	fibronectin binding	1/8(30)
471	GO:0003190	atrioventricular valve formation	2/8(30)
474	GO:0003700	transcription factor activity, sequence-specific DNA binding	4/7(30)
3198	GO:0019901	protein kinase binding	1/3(9)

Node FICEDULA / Ficedula albicollis

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