BOP - Node BOP11

Node summary

Genes	15285
Split time	22.93
Descendant nodes	LYCOCORAX BOP9
Ancestral node	BOP13

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CAFE summary

Expansions	356 (17 rapid)
Contractions	246 (2 rapid)
Extinctions	95

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Family list

GO Terms

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Family ID	Gene Count	Change	Rapid (*)?	Exctinction (--)?

276	6	+1
2686	1	-1
2681	1	-1
99	12	+2
98	12	+2
90	11	-2
93	11	-1
94	9	+2
97	12	+1
96	12	+1
1172	3	+1
876	4	+2	*
2749	1	-1
2309	2	+1
2308	2	+1
2300	2	+1
2303	2	+1
2305	2	+1
2304	2	+1
2307	2	+1
2306	2	+1
179	7	+1
175	8	+2
171	7	+1
697	2	-2
9965	0	-1		--
9967	0	-1		--
9960	0	-1		--
9968	0	-1		--
258	6	+1
252	6	+2	*
2518	1	-1
2514	1	-1
2515	1	-1
2513	2	+1
1150	3	+1
1153	3	+2
2187	1	-2
153	8	+1
155	8	+1
154	7	-1
156	7	-1
159	5	-1
10231	0	-1		--
9942	0	-1		--
9941	0	-1		--
9946	0	-1		--
9947	0	-1		--
9948	0	-1		--
238	5	-1
239	6	+1
236	6	+1
230	6	+1
2531	1	-1
2534	2	+1
937	2	-1
2414	2	+1
1132	3	+1
2419	2	+1
2418	1	-1
2149	2	+1
2	81	+4
2416	1	-1
9920	0	-1		--
9921	0	-1		--
9923	0	-1		--
9924	0	-1		--
9926	0	-1		--
9927	0	-1		--
212	7	+2
2550	1	-1
2551	0	-2		--
914	3	+1
916	2	-1
912	2	-2
635	4	+2
1111	2	-1
1110	1	-1
1115	2	-1
1118	2	-1
195	6	+5	*
196	7	+1
192	7	+1
6	55	+3
495	4	+1
496	4	+1
497	4	+1
492	4	+1
493	4	+1
9907	0	-1		--
9904	0	-1		--
9902	0	-1		--
9901	0	-1		--
9909	0	-1		--
446	4	+2	*
977	3	+1
976	3	+1
975	2	-1
974	3	+1
972	2	-1
971	3	+1
310	5	+1
317	5	+1
2299	2	+1
2298	2	+1
2292	1	-1
2290	2	+1
2297	2	+1
2296	2	+1
2295	2	+1
873	3	+1
2746	1	-1
1090	2	-1
1092	2	-1
959	2	-1
958	3	+1
951	3	+1
950	3	+1
953	3	+1
955	3	+1
957	3	+1
1662	2	+1
591	3	-1
595	4	+2
335	6	+3
334	6	+3
331	5	+1
332	5	+1
451	4	+1
455	4	+1
2465	2	+1
2468	2	+1
2469	2	+1
1026	3	+1
1021	3	+1
1020	3	+1
1023	2	-1
9659	0	-1		--
572	4	+1
570	4	+1
576	4	+1
574	3	-1
355	5	+1
353	5	+1
2193	1	-2
2257	2	+1
2256	2	+1
2255	2	+1
2251	2	+1
2075	2	+1
295	6	+3
2442	1	-1
2445	1	-1
558	4	+1
556	4	+2
1193	3	+1
2275	2	+1
2274	2	+1
2271	2	+1
2270	2	+1
2273	1	-1
2272	2	+1
2278	2	+1
2054	2	+1
9986	0	-1		--
9987	0	-1		--
9984	0	-1		--
9982	0	-1		--
9980	0	-1		--
410	3	-1
2428	2	+1
2429	1	-1
2420	2	+1
2422	1	-1
2425	1	-1
9616	0	-1		--
2166	1	-1
9894	0	-1		--
9896	0	-1		--
9897	0	-1		--
9892	0	-1		--
9893	0	-1		--
536	5	+3	*
534	3	-1
532	4	+1
531	4	+1
538	4	+1
2213	2	+1
2212	2	+1
2217	2	+1
2216	2	+1
2215	2	+1
2219	2	+1
2218	2	+1
10243	0	-1		--
1019	2	-1
1016	3	+1
1010	3	+1
1012	3	+1
432	4	+1
1057	3	+1
612	3	-1
615	4	+1
519	4	+1
511	4	+1
513	4	+1
512	4	+1
515	4	+1
514	4	+1
8475	0	-2		--
2239	2	+1
2233	2	+1
3	66	-1
1033	3	+1
1030	2	-1
1036	2	-1
1035	3	+1
2392	2	+1
2393	2	+1
2390	2	+1
2391	2	+1
2398	1	-1
2171	1	-2
2174	2	+1
9884	0	-1		--
601	4	+1
1206	3	+1
9882	0	-1		--
2614	1	-1
7	54	+2
2378	2	+1
2375	2	+1
2377	1	-1
2370	1	-1
2371	1	-1
2373	2	+1
1875	1	-1
2117	1	-2
2586	2	+1
280	6	+2	*
2635	1	-1
2630	1	-1
9598	0	-1		--
9594	0	-1		--
10262	0	-1		--
10266	0	-1		--
760	3	+1
1078	2	-1
2250	2	+1
2358	2	+1
2352	1	-1
2350	1	-1
1790	1	-1
1025	2	-1
9066	0	-2		--
1987	2	+1
2483	1	-1
2337	2	+1
2339	2	+1
120	10	+2
121	10	+1
124	10	+1
125	8	-2
127	9	+1
128	10	+2
9869	0	-1		--
9868	0	-1		--
9863	0	-1		--
9862	0	-1		--
9865	0	-1		--
9867	0	-1		--
9866	0	-1		--
1519	2	+1
989	3	+1
980	3	+1
981	3	+1
987	2	-1
985	3	+1
2672	1	-1
2677	1	-1
477	4	+2	*
2317	1	-2
2313	1	-1
2310	2	+1
100	11	-1
101	12	+2
106	12	+3	*
107	11	+1
1757	1	-1
1288	2	+1
688	4	+1
683	4	+1
8495	0	-2		--
245	6	-1
246	6	+1
241	6	+1
240	6	+1
243	6	+1
242	6	+1
2156	2	+1
2691	1	-1
381	5	+1
387	5	+2
2198	2	+1
164	8	+1
161	8	+2
162	7	+2
809	3	+1
800	3	+1
9977	0	-1		--
9976	0	-1		--
9973	0	-1		--
9972	0	-1		--
9979	0	-1		--
9978	0	-1		--
226	5	-2
223	7	+1
222	7	+2
221	5	-1
2507	1	-1
1120	3	+1
1121	2	-1
1126	3	+1
9992	0	-1		--
146	7	-1
144	6	-2
140	9	+4	*
149	8	+1
2715	1	-1
827	4	+2	*
11	43	+1
19	32	+2
18	32	+1
9955	0	-1		--
9950	0	-1		--
9952	0	-1		--
200	6	+1
204	7	+1
209	7	+1
836	3	-1
835	3	+1
2526	1	-1
2522	1	-1
2529	1	-1
402	5	+2
1106	2	-1
1104	3	+1
1103	3	+1
1100	2	-1
1108	2	-1
1109	2	-1
1896	2	+1
4	64	+5
2776	1	-1
2777	1	-1
3079	2	+1
489	3	-2
487	4	+1
9932	0	-1		--
9937	0	-1		--
9936	0	-1		--
9935	0	-1		--
2543	2	+1
2540	2	+1
2549	1	-1
2548	2	+1
906	3	+1
24	29	+1
26	6	-26	*
22	30	+3
23	29	-1
28	24	+2
1060	2	-1
1063	2	-1
1066	3	+1
2288	2	+1
2289	2	+1
2280	2	+1
2282	2	+1
2284	2	+1
2285	2	+1
2287	2	+1
189	7	+1
9970	0	-1		--
9626	0	-1		--
8	52	-1
9911	0	-1		--
9910	0	-1		--
9912	0	-1		--
9919	0	-1		--
9918	0	-1		--
2568	2	+1
2561	1	-1
964	3	+1
965	3	+1
966	3	+1
962	3	+1
969	3	+1
647	4	+2
309	5	+1
301	5	+1
304	3	-2
307	6	+3
2007	2	+1
1906	1	-1
1085	2	-1
1083	3	+1
1089	3	+1
1331	2	-1
39	20	-1
38	20	+1
32	19	-3
31	21	+2
30	24	+3
36	21	+3
35	23	+4	*
34	20	-1
580	4	+1
588	5	+4	*
323	5	+1
326	5	+2
324	4	+1
328	5	+1
9899	0	-1		--
2249	1	-1
2244	2	+1
2245	2	+1
2247	2	+1
2243	2	+1
2068	1	-2
465	3	-1
1356	2	+1
10289	0	-1		--
289	5	+1
285	5	+1
2476	1	-1
2473	1	-1
9644	0	-1		--
9646	0	-1		--
560	4	+1
561	4	+1
49	15	-2
47	18	+1
44	17	-1
42	18	-1
41	19	+2
2268	2	+1
2262	2	+1
2263	2	+1
2260	2	+1
2261	2	+1
2266	2	+1
2267	2	+1
2265	2	+1
9413	0	-1		--
9619	0	-1		--
9872	0	-1		--
2459	2	+1
2455	1	-1
2454	1	-1
655	3	-1
543	4	+1
540	4	+1
547	4	+1
361	5	+1
2204	2	+1
2205	2	+1
2207	2	+1
2209	2	+1
55	17	+2
54	17	+1
57	17	+1
51	18	+1
53	16	-1
9994	0	-1		--
425	4	+1
426	5	+2
2333	1	-1
2334	2	+1
2439	2	+1
2433	1	-1
2431	1	-1
2430	1	-1
2437	1	-1
9601	0	-1		--
1397	3	+1
524	3	-1
526	4	+1
520	3	-1
523	4	+1
528	4	+1
2489	1	-1
2228	2	+1
2227	2	+1
2224	2	+1
2225	2	+1
2222	2	+1
2223	2	+1
2220	2	+1
2221	2	+1
1007	3	+1
1006	2	-1
1004	3	+1
1003	3	+1
1001	3	+1
2660	2	+1
2661	1	-1
2147	2	+1
2413	1	-1
60	15	+1
63	16	+3
66	16	+4	*
67	16	+4	*
68	14	+1
507	3	-1
504	4	+1
1210	3	+2
2606	2	+1
2602	1	-1
751	4	+1
1027	2	-1
1028	3	+1
10328	0	-1		--
2381	2	+1
2380	1	-1
2384	2	+1
1279	3	+1
611	4	+1
2599	1	-1
2626	1	-1
2625	2	+1
10277	0	-1		--
76	15	+3	*
75	14	+1
72	14	+1
71	13	-1
70	13	+1
78	15	+4	*
1041	3	+1
1047	3	+1
1044	3	+1
865	3	+1
864	3	+1
2755	1	-1
2321	2	+1
2320	2	+1
2326	1	-1
2369	2	+1
2365	2	+1
2364	2	+1
2363	2	+1
2362	2	+1
2106	2	+1
9	48	+1
894	3	+1
896	3	+1
2492	2	+1
2494	2	+1
2647	1	-1
9070	0	-2		--
9881	0	-1		--
10292	0	-1		--
2345	1	-1
2344	2	+1
2343	2	+1
2342	1	-1
2348	1	-1
132	8	+1
131	9	+1
130	9	+1
138	9	+2
1	81	-5
89	13	+2
83	10	+4	*
80	12	-1
86	12	-1
87	12	+1
84	13	+1
85	12	-1
9878	0	-1		--
9876	0	-1		--
9877	0	-1		--
9874	0	-1		--
9875	0	-1		--
9873	0	-1		--
9870	0	-1		--
3888	0	-3		--
2484	1	-1
1296	2	+1
995	3	+1
994	3	+1
996	2	-1
991	3	+1
993	3	+1
2405	2	+1
2402	0	-3	*	--
2151	1	-1
2401	2	+1
2328	2	+1
2499	2	+1
117	10	+1
1488	2	+1

Family ID	GO ID	GO term	# genes w/ GO ID

9070	GO:0098641	cadherin binding involved in cell-cell adhesion	1/4(6)
9070	GO:0045202	synapse	1/4(6)
162	GO:0005216	ion channel activity	1/9(57)
162	GO:0006816	calcium ion transport	1/9(57)
9932	GO:0004177	aminopeptidase activity	2/2(3)
504	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	2/6(29)
504	GO:0007040	lysosome organization	1/6(29)
9937	GO:0004788	thiamine diphosphokinase activity	2/2(3)
9936	GO:0003824	catalytic activity	1/2(3)
9935	GO:0042384	cilium assembly	2/2(3)
1790	GO:0016407	acetyltransferase activity	7/8(16)
2317	GO:0003700	transcription factor activity, sequence-specific DNA binding	3/6(13)
1063	GO:0007010	cytoskeleton organization	1/6(19)
2310	GO:0006810	transport	1/2(13)
1066	GO:0003735	structural constituent of ribosome	1/3(19)
1066	GO:0006396	RNA processing	1/3(19)
295	GO:0006338	chromatin remodeling	1/6(39)
1662	GO:0044822	poly(A) RNA binding	2/2(16)
591	GO:0005516	calmodulin binding	4/7(27)
1085	GO:0000166	nucleotide binding	1/6(19)
1083	GO:0003824	catalytic activity	4/4(19)
1121	GO:0016020	membrane	4/6(19)
1126	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2/4(18)
192	GO:0003779	actin binding	7/11(51)
276	GO:0005085	guanyl-nucleotide exchange factor activity	4/8(41)
2543	GO:0004175	endopeptidase activity	2/2(11)
2549	GO:0005615	extracellular space	2/4(11)
2548	GO:0003779	actin binding	2/2(11)
524	GO:0003872	6-phosphofructokinase activity	4/8(28)
524	GO:0000166	nucleotide binding	1/8(28)
2380	GO:0004252	serine-type endopeptidase activity	1/5(12)
2268	GO:0018024	histone-lysine N-methyltransferase activity	1/2(13)
2268	GO:0042799	histone methyltransferase activity (H4-K20 specific)	1/2(13)
520	GO:0005245	voltage-gated calcium channel activity	4/9(29)
1019	GO:0005524	ATP binding	1/7(20)
1019	GO:0000166	nucleotide binding	3/7(20)
523	GO:0005102	receptor binding	2/6(28)
2263	GO:0008270	zinc ion binding	2/2(13)
2261	GO:0000166	nucleotide binding	1/2(13)
1010	GO:0016740	transferase activity	1/4(20)
1010	GO:0004142	diacylglycerol cholinephosphotransferase activity	2/4(20)
2267	GO:0003713	transcription coactivator activity	1/2(13)
1012	GO:0003713	transcription coactivator activity	1/3(20)
1012	GO:0000398	mRNA splicing, via spliceosome	1/3(20)
1004	GO:0008270	zinc ion binding	1/3(20)
1331	GO:0003676	nucleic acid binding	3/6(17)
446	GO:0005089	Rho guanyl-nucleotide exchange factor activity	1/4(32)
100	GO:0005215	transporter activity	17/23(90)
100	GO:0022857	transmembrane transporter activity	1/23(90)
101	GO:0016020	membrane	2/23(89)
106	GO:0003676	nucleic acid binding	2/18(84)
106	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/18(84)
106	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/18(84)
106	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	1/18(84)
106	GO:0001046	core promoter sequence-specific DNA binding	3/18(84)
107	GO:0005198	structural molecule activity	13/21(83)
39	GO:0001948	glycoprotein binding	2/43(155)
39	GO:0005198	structural molecule activity	14/43(155)
38	GO:0070062	extracellular exosome	3/36(156)
38	GO:0005102	receptor binding	7/36(156)
38	GO:0003735	structural constituent of ribosome	1/36(156)
38	GO:0008061	chitin binding	1/36(156)
38	GO:0008233	peptidase activity	2/36(156)
38	GO:0004857	enzyme inhibitor activity	1/36(156)
906	GO:0005509	calcium ion binding	3/4(22)
1003	GO:0003779	actin binding	1/4(20)
1003	GO:0030018	Z disc	1/4(20)
32	GO:0002020	protease binding	1/58(170)
32	GO:0016525	negative regulation of angiogenesis	2/58(170)
32	GO:0005615	extracellular space	19/58(170)
32	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	1/58(170)
32	GO:0004867	serine-type endopeptidase inhibitor activity	8/58(170)
31	GO:0004252	serine-type endopeptidase activity	2/24(171)
31	GO:0001964	startle response	2/24(171)
31	GO:0016020	membrane	2/24(171)
31	GO:0008344	adult locomotory behavior	2/24(171)
31	GO:0003682	chromatin binding	1/24(171)
30	GO:0017147	Wnt-protein binding	1/37(182)
30	GO:0001540	beta-amyloid binding	1/37(182)
30	GO:0005041	low-density lipoprotein receptor activity	2/37(182)
30	GO:0005509	calcium ion binding	6/37(182)
30	GO:0001948	glycoprotein binding	1/37(182)
36	GO:0005112	Notch binding	10/30(160)
36	GO:0001047	core promoter binding	1/30(160)
36	GO:0005509	calcium ion binding	5/30(160)
35	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	2/37(166)
35	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	6/37(166)
35	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/37(166)
35	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	1/37(166)
35	GO:0003677	DNA binding	3/37(166)
34	GO:0001948	glycoprotein binding	1/45(166)
34	GO:0005178	integrin binding	1/45(166)
34	GO:0005102	receptor binding	2/45(166)
34	GO:0005509	calcium ion binding	28/45(166)
647	GO:0004175	endopeptidase activity	1/4(25)
647	GO:0004222	metalloendopeptidase activity	1/4(25)
2166	GO:0006904	vesicle docking involved in exocytosis	3/7(14)
432	GO:0005085	guanyl-nucleotide exchange factor activity	2/6(32)
2614	GO:0003723	RNA binding	1/3(10)
331	GO:0003676	nucleic acid binding	3/8(36)
331	GO:0000166	nucleotide binding	1/8(36)
332	GO:0055085	transmembrane transport	3/8(36)
332	GO:0015136	sialic acid transmembrane transporter activity	2/8(36)
1906	GO:0003824	catalytic activity	5/7(15)
6	GO:0005200	structural constituent of cytoskeleton	1/103(437)
6	GO:1990126	retrograde transport, endosome to plasma membrane	2/103(437)
6	GO:0007165	signal transduction	2/103(437)
6	GO:0003676	nucleic acid binding	2/103(437)
6	GO:0003950	NAD+ ADP-ribosyltransferase activity	2/103(437)
6	GO:0035556	intracellular signal transduction	1/103(437)
6	GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1/103(437)
6	GO:0000149	SNARE binding	1/103(437)
6	GO:0019887	protein kinase regulator activity	1/103(437)
6	GO:0004672	protein kinase activity	2/103(437)
6	GO:0008134	transcription factor binding	2/103(437)
6	GO:0090090	negative regulation of canonical Wnt signaling pathway	3/103(437)
6	GO:0044212	transcription regulatory region DNA binding	1/103(437)
6	GO:0005216	ion channel activity	2/103(437)
6	GO:0017137	Rab GTPase binding	1/103(437)
6	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/103(437)
6	GO:0045893	positive regulation of transcription, DNA-templated	2/103(437)
6	GO:0007520	myoblast fusion	2/103(437)
6	GO:0001085	RNA polymerase II transcription factor binding	2/103(437)
6	GO:0010613	positive regulation of cardiac muscle hypertrophy	1/103(437)
6	GO:0008093	cytoskeletal adaptor activity	1/103(437)
6	GO:0016567	protein ubiquitination	3/103(437)
6	GO:0005634	nucleus	2/103(437)
1021	GO:0003676	nucleic acid binding	2/2(20)
99	GO:0005085	guanyl-nucleotide exchange factor activity	9/19(91)
98	GO:0015171	amino acid transmembrane transporter activity	16/19(91)
2245	GO:0005524	ATP binding	2/2(13)
90	GO:0005198	structural molecule activity	18/37(97)
93	GO:0005254	chloride channel activity	1/26(96)
93	GO:0005253	anion channel activity	1/26(96)
93	GO:0008271	secondary active sulfate transmembrane transporter activity	10/26(96)
93	GO:0004871	signal transducer activity	3/26(96)
97	GO:0003958	NADPH-hemoprotein reductase activity	3/19(91)
97	GO:0005272	sodium channel activity	3/19(91)
97	GO:0005261	cation channel activity	1/19(91)
97	GO:0004517	nitric-oxide synthase activity	3/19(91)
96	GO:0004725	protein tyrosine phosphatase activity	3/21(93)
96	GO:0004722	protein serine/threonine phosphatase activity	1/21(93)
96	GO:0030234	enzyme regulator activity	1/21(93)
96	GO:0004438	phosphatidylinositol-3-phosphatase activity	6/21(93)
9942	GO:0003824	catalytic activity	1/2(3)
9948	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/2(3)
558	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/4(27)
556	GO:0044822	poly(A) RNA binding	1/4(27)
238	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	7/14(45)
238	GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/14(45)
239	GO:0003677	DNA binding	7/9(44)
236	GO:0008378	galactosyltransferase activity	6/10(45)
230	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/10(47)
230	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/10(47)
230	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/10(47)
230	GO:0001047	core promoter binding	1/10(47)
426	GO:0008270	zinc ion binding	1/6(32)
2345	GO:0003824	catalytic activity	2/4(12)
2345	GO:0000166	nucleotide binding	2/4(12)
2228	GO:0051726	regulation of cell cycle	2/2(13)
1057	GO:0030165	PDZ domain binding	1/2(19)
2227	GO:0008270	zinc ion binding	1/2(13)
1193	GO:0004843	thiol-dependent ubiquitin-specific protease activity	1/3(18)
2225	GO:0015631	tubulin binding	1/2(13)
2222	GO:0030449	regulation of complement activation	1/2(13)
2223	GO:0003779	actin binding	1/2(13)
2220	GO:0003676	nucleic acid binding	1/2(13)
2221	GO:0005524	ATP binding	2/2(13)
1	GO:0001223	transcription coactivator binding	2/267(729)
1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	3/267(729)
1	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/267(729)
1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	6/267(729)
1	GO:0003676	nucleic acid binding	66/267(729)
1	GO:0001046	core promoter sequence-specific DNA binding	1/267(729)
1	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9/267(729)
1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	2/267(729)
1	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/267(729)
146	GO:0016787	hydrolase activity	7/16(61)
146	GO:0004771	sterol esterase activity	1/16(61)
146	GO:0016788	hydrolase activity, acting on ester bonds	1/16(61)
1279	GO:0000185	activation of MAPKKK activity	1/3(17)
1172	GO:0005518	collagen binding	2/3(18)
140	GO:0000150	recombinase activity	1/6(64)
140	GO:0000166	nucleotide binding	2/6(64)
612	GO:0005216	ion channel activity	2/8(26)
611	GO:0004842	ubiquitin-protein transferase activity	3/5(26)
615	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/6(26)
1007	GO:0004077	biotin-[acetyl-CoA-carboxylase] ligase activity	3/3(20)
1006	GO:0001933	negative regulation of protein phosphorylation	1/6(20)
2377	GO:0016020	membrane	1/5(12)
515	GO:0005856	cytoskeleton	1/6(29)
515	GO:0030674	protein binding, bridging	1/6(29)
515	GO:0090162	establishment of epithelial cell polarity	1/6(29)
2342	GO:0015187	glycine transmembrane transporter activity	2/4(12)
1288	GO:0003676	nucleic acid binding	2/2(17)
2531	GO:0071889	14-3-3 protein binding	2/4(11)
2531	GO:0042803	protein homodimerization activity	1/4(11)
2224	GO:0050839	cell adhesion molecule binding	1/2(13)
2715	GO:0005216	ion channel activity	1/3(10)
2348	GO:0005509	calcium ion binding	3/4(12)
9986	GO:0007224	smoothened signaling pathway	2/2(3)
131	GO:0005216	ion channel activity	7/13(69)
131	GO:0005249	voltage-gated potassium channel activity	1/13(69)
130	GO:0001849	complement component C1q binding	1/14(69)
130	GO:0005178	integrin binding	1/14(69)
130	GO:0005201	extracellular matrix structural constituent	2/14(69)
130	GO:0005509	calcium ion binding	1/14(69)
495	GO:0003676	nucleic acid binding	2/6(29)
496	GO:0007605	sensory perception of sound	1/6(29)
496	GO:0016020	membrane	2/6(29)
497	GO:0005096	GTPase activator activity	2/6(29)
497	GO:0007165	signal transduction	1/6(29)
493	GO:0002009	morphogenesis of an epithelium	2/6(29)
493	GO:0005509	calcium ion binding	1/6(29)
493	GO:0007154	cell communication	1/6(29)
24	GO:0008233	peptidase activity	2/54(230)
24	GO:0004175	endopeptidase activity	4/54(230)
24	GO:0004222	metalloendopeptidase activity	16/54(230)
26	GO:0005200	structural constituent of cytoskeleton	54/166(216)
22	GO:0005216	ion channel activity	31/52(233)
23	GO:0000287	magnesium ion binding	2/61(232)
23	GO:0004672	protein kinase activity	17/61(232)
23	GO:0000166	nucleotide binding	18/61(232)
28	GO:0048675	axon extension	2/39(187)
28	GO:0002292	T cell differentiation involved in immune response	1/39(187)
28	GO:0070062	extracellular exosome	1/39(187)
28	GO:0016020	membrane	4/39(187)
28	GO:0004888	transmembrane signaling receptor activity	2/39(187)
28	GO:0004872	receptor activity	1/39(187)
28	GO:0005886	plasma membrane	2/39(187)
28	GO:0001843	neural tube closure	1/39(187)
28	GO:0030215	semaphorin receptor binding	6/39(187)
2156	GO:0016020	membrane	1/2(14)
2405	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2(11)
402	GO:0004872	receptor activity	1/5(33)
8495	GO:0016787	hydrolase activity	3/5(7)
2401	GO:0004871	signal transducer activity	1/2(12)
937	GO:0003677	DNA binding	4/7(22)
9066	GO:0005509	calcium ion binding	1/4(6)
9904	GO:0016491	oxidoreductase activity	2/2(3)
9902	GO:0007094	mitotic spindle assembly checkpoint	2/2(3)
9901	GO:0001945	lymph vessel development	2/2(3)
9909	GO:0016746	transferase activity, transferring acyl groups	1/2(3)
1060	GO:0004871	signal transducer activity	2/6(19)
2489	GO:0015631	tubulin binding	3/4(11)
827	GO:0000386	second spliceosomal transesterification activity	1/2(23)
89	GO:0000166	nucleotide binding	9/18(97)
83	GO:0016020	membrane	3/5(101)
80	GO:0005215	transporter activity	7/26(103)
86	GO:0003824	catalytic activity	2/27(97)
86	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	13/27(97)
87	GO:0005215	transporter activity	5/20(97)
87	GO:0022857	transmembrane transporter activity	5/20(97)
87	GO:0005275	amine transmembrane transporter activity	2/20(97)
87	GO:0015226	carnitine transmembrane transporter activity	1/20(97)
84	GO:0000166	nucleotide binding	12/25(100)
85	GO:0004866	endopeptidase inhibitor activity	13/25(99)
2308	GO:0008270	zinc ion binding	1/2(13)
2300	GO:0000922	spindle pole	1/2(13)
2303	GO:0003351	epithelial cilium movement	1/2(13)
2307	GO:0004856	xylulokinase activity	1/2(13)
2306	GO:0004842	ubiquitin-protein transferase activity	2/2(13)
9870	GO:0000010	trans-hexaprenyltranstransferase activity	2/2(3)
7	GO:0000166	nucleotide binding	21/107(435)
7	GO:0000287	magnesium ion binding	5/107(435)
7	GO:0004672	protein kinase activity	29/107(435)
2289	GO:0016020	membrane	1/2(13)
580	GO:0004888	transmembrane signaling receptor activity	4/5(27)
580	GO:0003725	double-stranded RNA binding	1/5(27)
2280	GO:0002088	lens development in camera-type eye	1/2(13)
1132	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/4(18)
2282	GO:0019904	protein domain specific binding	1/2(13)
2285	GO:0044822	poly(A) RNA binding	1/2(13)
245	GO:0005102	receptor binding	1/14(44)
245	GO:0016790	thiolester hydrolase activity	2/14(44)
246	GO:0008270	zinc ion binding	2/8(44)
241	GO:0000226	microtubule cytoskeleton organization	2/10(44)
241	GO:0016192	vesicle-mediated transport	2/10(44)
240	GO:0000166	nucleotide binding	5/9(44)
243	GO:0005509	calcium ion binding	1/9(44)
243	GO:0019899	enzyme binding	1/9(44)
243	GO:0002175	protein localization to paranode region of axon	1/9(44)
242	GO:0003677	DNA binding	2/8(44)
242	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/8(44)
242	GO:0001046	core promoter sequence-specific DNA binding	2/8(44)
149	GO:0048365	Rac GTPase binding	1/13(60)
149	GO:0051015	actin filament binding	4/13(60)
972	GO:0005509	calcium ion binding	7/8(21)
2275	GO:0004197	cysteine-type endopeptidase activity	2/2(13)
2274	GO:0004649	poly(ADP-ribose) glycohydrolase activity	1/2(13)
2271	GO:0007067	mitotic nuclear division	2/2(13)
2272	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/2(13)
519	GO:0000166	nucleotide binding	5/6(29)
511	GO:0001085	RNA polymerase II transcription factor binding	1/6(29)
511	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/6(29)
2375	GO:0044822	poly(A) RNA binding	2/2(12)
513	GO:0003677	DNA binding	1/6(29)
513	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	2/6(29)
513	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/6(29)
512	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/6(29)
2370	GO:0015238	drug transmembrane transporter activity	1/5(12)
514	GO:0019901	protein kinase binding	2/6(29)
1001	GO:0003676	nucleic acid binding	1/3(20)
2373	GO:0016020	membrane	2/2(12)
138	GO:0014719	skeletal muscle satellite cell activation	2/12(64)
138	GO:0005509	calcium ion binding	1/12(64)
2459	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	2/2(11)
2455	GO:0004348	glucosylceramidase activity	3/4(11)
451	GO:0007015	actin filament organization	1/6(31)
455	GO:0004871	signal transducer activity	2/5(31)
1875	GO:0003824	catalytic activity	4/9(16)
179	GO:0000166	nucleotide binding	5/10(55)
9876	GO:0005484	SNAP receptor activity	1/2(3)
595	GO:0008376	acetylgalactosaminyltransferase activity	2/4(26)
175	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2/9(56)
175	GO:0003677	DNA binding	2/9(56)
9875	GO:0003677	DNA binding	2/2(3)
9872	GO:0004252	serine-type endopeptidase activity	1/2(3)
9873	GO:0008013	beta-catenin binding	2/2(3)
171	GO:0016757	transferase activity, transferring glycosyl groups	10/13(56)
976	GO:0005509	calcium ion binding	1/4(21)
975	GO:0000166	nucleotide binding	4/7(21)
974	GO:0005057	signal transducer activity, downstream of receptor	2/4(21)
2054	GO:0003824	catalytic activity	1/2(15)
971	GO:0005102	receptor binding	1/4(21)
2	GO:0000166	nucleotide binding	33/155(642)
2	GO:0003924	GTPase activity	35/155(642)
2	GO:0005509	calcium ion binding	2/155(642)
2	GO:0005525	GTP binding	32/155(642)
189	GO:0004407	histone deacetylase activity	1/8(51)
189	GO:0001025	RNA polymerase III transcription factor binding	1/8(51)
2117	GO:0005344	oxygen transporter activity	6/6(14)
1089	GO:0070062	extracellular exosome	1/4(19)
8475	GO:0005198	structural molecule activity	2/4(7)
9626	GO:0003713	transcription coactivator activity	2/3(4)
11	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	9/99(347)
11	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/99(347)
11	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/99(347)
11	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	3/99(347)
11	GO:0003677	DNA binding	30/99(347)
19	GO:0004890	GABA-A receptor activity	24/58(244)
19	GO:0005230	extracellular ligand-gated ion channel activity	10/58(244)
19	GO:0006811	ion transport	1/58(244)
18	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs	2/66(256)
18	GO:0004930	G-protein coupled receptor activity	1/66(256)
18	GO:0001594	trace-amine receptor activity	1/66(256)
18	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	4/66(256)
18	GO:0001587	Gq/11-coupled serotonin receptor activity	2/66(256)
18	GO:0001965	G-protein alpha-subunit binding	2/66(256)
18	GO:0004871	signal transducer activity	28/66(256)
865	GO:0005506	iron ion binding	2/4(23)
864	GO:0007275	multicellular organism development	2/4(23)
864	GO:0001736	establishment of planar polarity	2/4(23)
2755	GO:0016020	membrane	1/3(10)
2151	GO:0005344	oxygen transporter activity	3/6(14)
63	GO:0001641	group II metabotropic glutamate receptor activity	4/24(116)
63	GO:0004871	signal transducer activity	8/24(116)
355	GO:0003700	transcription factor activity, sequence-specific DNA binding	1/7(34)
355	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/7(34)
355	GO:0003676	nucleic acid binding	1/7(34)
9894	GO:0000976	transcription regulatory region sequence-specific DNA binding	2/2(3)
323	GO:0004867	serine-type endopeptidase inhibitor activity	6/8(37)
9897	GO:0008270	zinc ion binding	1/2(3)
326	GO:0005432	calcium:sodium antiporter activity	3/5(36)
324	GO:0008146	sulfotransferase activity	2/6(36)
9893	GO:0003676	nucleic acid binding	1/2(3)
9955	GO:0004298	threonine-type endopeptidase activity	1/2(3)
328	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/7(36)
328	GO:0003677	DNA binding	2/7(36)
9899	GO:0007368	determination of left/right symmetry	2/2(3)
9952	GO:0010506	regulation of autophagy	2/2(3)
200	GO:0016020	membrane	2/10(50)
204	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/11(49)
204	GO:0046983	protein dimerization activity	4/11(49)
209	GO:0009986	cell surface	3/10(49)
209	GO:0016020	membrane	2/10(49)
76	GO:0001948	glycoprotein binding	1/22(105)
76	GO:0005576	extracellular region	1/22(105)
76	GO:0001657	ureteric bud development	2/22(105)
75	GO:0005179	hormone activity	2/25(107)
75	GO:0005125	cytokine activity	2/25(107)
75	GO:0004745	retinol dehydrogenase activity	1/25(107)
75	GO:0008083	growth factor activity	11/25(107)
72	GO:0004252	serine-type endopeptidase activity	2/25(108)
72	GO:0016020	membrane	1/25(108)
72	GO:0005044	scavenger receptor activity	1/25(108)
71	GO:0001601	peptide YY receptor activity	7/30(108)
71	GO:0004930	G-protein coupled receptor activity	2/30(108)
71	GO:0004871	signal transducer activity	14/30(108)
70	GO:0004871	signal transducer activity	15/23(109)
655	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	4/9(25)
78	GO:0005216	ion channel activity	2/14(103)
78	GO:0005245	voltage-gated calcium channel activity	1/14(103)
1041	GO:0001786	phosphatidylserine binding	2/4(20)
9923	GO:0008260	3-oxoacid CoA-transferase activity	2/2(3)
1047	GO:0003677	DNA binding	4/4(20)
1044	GO:0007018	microtubule-based movement	2/4(20)
1044	GO:0030507	spectrin binding	1/4(20)
2339	GO:0003824	catalytic activity	2/2(12)
2233	GO:0001708	cell fate specification	1/2(13)
3079	GO:0004222	metalloendopeptidase activity	1/1(9)
2381	GO:0010314	phosphatidylinositol-5-phosphate binding	1/2(12)
2526	GO:0003779	actin binding	1/4(11)
2526	GO:0008017	microtubule binding	2/4(11)
697	GO:0003954	NADH dehydrogenase activity	2/8(25)
526	GO:0001733	galactosylceramide sulfotransferase activity	2/6(28)
2484	GO:0000166	nucleotide binding	2/4(11)
2529	GO:0004896	cytokine receptor activity	4/4(11)
2483	GO:0016020	membrane	2/4(11)
2483	GO:0005227	calcium activated cation channel activity	2/4(11)
543	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/5(28)
540	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	1/6(28)
540	GO:0016491	oxidoreductase activity	1/6(28)
547	GO:0003677	DNA binding	2/4(28)
2244	GO:0005615	extracellular space	1/2(13)
8	GO:0003774	motor activity	3/108(417)
8	GO:0007165	signal transduction	1/108(417)
8	GO:0000146	microfilament motor activity	8/108(417)
8	GO:0000166	nucleotide binding	38/108(417)
68	GO:0004089	carbonate dehydratase activity	13/26(110)
68	GO:0004064	arylesterase activity	2/26(110)
995	GO:0003824	catalytic activity	3/4(21)
994	GO:0005102	receptor binding	2/4(21)
996	GO:0016020	membrane	3/7(21)
993	GO:0005525	GTP binding	3/4(21)
2468	GO:0003676	nucleic acid binding	1/2(11)
2469	GO:1903401	L-lysine transmembrane transport	1/2(11)
2469	GO:0015181	arginine transmembrane transporter activity	1/2(11)
120	GO:0004252	serine-type endopeptidase activity	2/14(75)
120	GO:0004175	endopeptidase activity	4/14(75)
120	GO:0002020	protease binding	1/14(75)
121	GO:0002091	negative regulation of receptor internalization	3/17(74)
121	GO:0016020	membrane	1/17(74)
121	GO:0060348	bone development	2/17(74)
121	GO:0051965	positive regulation of synapse assembly	1/17(74)
121	GO:0005518	collagen binding	1/17(74)
121	GO:0001530	lipopolysaccharide binding	1/17(74)
121	GO:0001968	fibronectin binding	1/17(74)
124	GO:0000166	nucleotide binding	12/14(73)
125	GO:0005201	extracellular matrix structural constituent	6/22(72)
125	GO:0001540	beta-amyloid binding	1/22(72)
125	GO:0005198	structural molecule activity	1/22(72)
127	GO:0003779	actin binding	1/16(70)
127	GO:0005216	ion channel activity	5/16(70)
128	GO:0005543	phospholipid binding	1/12(70)
128	GO:0016021	integral component of membrane	1/12(70)
128	GO:0016020	membrane	2/12(70)
9987	GO:0042802	identical protein binding	2/2(3)
9984	GO:0001227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	1/2(3)
9984	GO:0005739	mitochondrion	1/2(3)
9982	GO:0006914	autophagy	2/2(3)
9980	GO:0004129	cytochrome-c oxidase activity	2/2(3)
132	GO:0004721	phosphoprotein phosphatase activity	8/14(68)
528	GO:0005044	scavenger receptor activity	1/5(28)
528	GO:0003682	chromatin binding	1/5(28)
2068	GO:0016020	membrane	1/6(15)
2068	GO:0001764	neuron migration	1/6(15)
2413	GO:0016740	transferase activity	1/4(11)
2413	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	1/4(11)
410	GO:0003779	actin binding	1/8(32)
2414	GO:0003677	DNA binding	1/2(11)
2416	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/3(11)
2418	GO:0000989	transcription factor activity, transcription factor binding	3/4(11)
2365	GO:0045892	negative regulation of transcription, DNA-templated	2/2(12)
2439	GO:0042803	protein homodimerization activity	1/2(11)
310	GO:0006351	transcription, DNA-templated	1/7(37)
310	GO:0003677	DNA binding	2/7(37)
317	GO:0043410	positive regulation of MAPK cascade	2/7(37)
317	GO:0016462	pyrophosphatase activity	1/7(37)
317	GO:0019894	kinesin binding	2/7(37)
3888	GO:0016010	dystrophin-associated glycoprotein complex	1/6(9)
3888	GO:0016011	dystroglycan complex	2/6(9)
3888	GO:0005886	plasma membrane	2/6(9)
9659	GO:0005737	cytoplasm	1/3(4)
9911	GO:0003676	nucleic acid binding	1/2(3)
9910	GO:0018025	calmodulin-lysine N-methyltransferase activity	1/2(3)
9912	GO:0030165	PDZ domain binding	1/2(3)
836	GO:0017080	sodium channel regulator activity	2/9(23)
836	GO:0030198	extracellular matrix organization	1/9(23)
835	GO:0008306	associative learning	1/4(23)
9918	GO:0003676	nucleic acid binding	1/2(3)
3	GO:0000287	magnesium ion binding	1/139(535)
3	GO:0000166	nucleotide binding	72/139(535)
3	GO:0003779	actin binding	2/139(535)
3	GO:0004713	protein tyrosine kinase activity	1/139(535)
3	GO:0004672	protein kinase activity	11/139(535)
3	GO:0005524	ATP binding	1/139(535)
2661	GO:0042393	histone binding	1/3(10)
381	GO:0000166	nucleotide binding	2/5(33)
387	GO:0008307	structural constituent of muscle	1/6(33)
387	GO:0015278	calcium-release channel activity	1/6(33)
387	GO:0051209	release of sequestered calcium ion into cytosol	2/6(33)
9874	GO:0004001	adenosine kinase activity	2/2(3)
9967	GO:0008270	zinc ion binding	2/2(3)
2298	GO:0017137	Rab GTPase binding	1/2(13)
2292	GO:0004867	serine-type endopeptidase inhibitor activity	1/5(13)
2292	GO:0003677	DNA binding	1/5(13)
570	GO:0008270	zinc ion binding	3/6(27)
2297	GO:0016020	membrane	2/2(13)
576	GO:0004725	protein tyrosine phosphatase activity	1/5(27)
2295	GO:0070062	extracellular exosome	1/2(13)
574	GO:0000287	magnesium ion binding	2/8(27)
574	GO:0003723	RNA binding	2/8(27)
574	GO:0004721	phosphoprotein phosphatase activity	3/8(27)
60	GO:0005737	cytoplasm	1/27(120)
60	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/27(120)
60	GO:0005200	structural constituent of cytoskeleton	1/27(120)
60	GO:0005524	ATP binding	1/27(120)
60	GO:0000166	nucleotide binding	9/27(120)
258	GO:0000166	nucleotide binding	3/8(42)
2193	GO:0005085	guanyl-nucleotide exchange factor activity	4/7(14)
66	GO:0001085	RNA polymerase II transcription factor binding	1/22(115)
66	GO:0001105	RNA polymerase II transcription coactivator activity	1/22(115)
66	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	1/22(115)
66	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	5/22(115)
66	GO:0003677	DNA binding	5/22(115)
67	GO:0005216	ion channel activity	7/22(112)
2198	GO:0016925	protein sumoylation	1/2(13)
155	GO:0003677	DNA binding	4/14(59)
2205	GO:0003676	nucleic acid binding	1/2(13)
2207	GO:0008157	protein phosphatase 1 binding	1/2(13)
2209	GO:0008380	RNA splicing	2/2(13)
2433	GO:0070324	thyroid hormone binding	4/4(11)
2369	GO:0000166	nucleotide binding	1/2(12)
1033	GO:0003677	DNA binding	2/4(20)
1030	GO:0044822	poly(A) RNA binding	2/6(20)
1030	GO:0016020	membrane	2/6(20)
2364	GO:0008270	zinc ion binding	2/2(12)
1036	GO:0004806	triglyceride lipase activity	1/7(20)
1036	GO:0052689	carboxylic ester hydrolase activity	1/7(20)
1035	GO:0006810	transport	3/3(20)
1210	GO:0005089	Rho guanyl-nucleotide exchange factor activity	1/2(18)
2430	GO:0016787	hydrolase activity	4/4(11)
465	GO:0006355	regulation of transcription, DNA-templated	1/10(31)
465	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/10(31)
465	GO:0003677	DNA binding	1/10(31)
2422	GO:0001948	glycoprotein binding	2/4(11)
2422	GO:0006954	inflammatory response	2/4(11)
2425	GO:0005576	extracellular region	1/4(11)
9868	GO:0005524	ATP binding	1/2(3)
164	GO:0016020	membrane	3/13(57)
9863	GO:0008179	adenylate cyclase binding	1/2(3)
9862	GO:0005634	nucleus	1/2(3)
161	GO:0003824	catalytic activity	1/10(57)
161	GO:0007165	signal transduction	1/10(57)
161	GO:0042803	protein homodimerization activity	2/10(57)
9867	GO:0008146	sulfotransferase activity	1/2(3)
9866	GO:0003677	DNA binding	2/2(3)
964	GO:0005911	cell-cell junction	1/4(21)
965	GO:0008565	protein transporter activity	3/4(21)
966	GO:0004550	nucleoside diphosphate kinase activity	1/4(21)
966	GO:0000166	nucleotide binding	1/4(21)
969	GO:0008289	lipid binding	2/3(21)
1106	GO:0000166	nucleotide binding	3/5(19)
1104	GO:0016740	transferase activity	2/4(19)
1104	GO:0015020	glucuronosyltransferase activity	1/4(19)
2518	GO:0035255	ionotropic glutamate receptor binding	3/4(11)
1103	GO:0003779	actin binding	1/4(19)
1100	GO:0003824	catalytic activity	2/5(19)
2514	GO:0043015	gamma-tubulin binding	1/3(11)
1108	GO:0005095	GTPase inhibitor activity	2/6(19)
1109	GO:0003779	actin binding	3/6(19)
9616	GO:0007010	cytoskeleton organization	1/3(4)
2635	GO:0003840	gamma-glutamyltransferase activity	3/3(10)
9619	GO:0006891	intra-Golgi vesicle-mediated transport	1/3(4)
9598	GO:0019901	protein kinase binding	1/3(4)
9594	GO:0003954	NADH dehydrogenase activity	2/3(4)
873	GO:0005078	MAP-kinase scaffold activity	1/4(23)
2746	GO:0007009	plasma membrane organization	1/3(10)
2746	GO:0005543	phospholipid binding	1/3(10)
9	GO:0007626	locomotory behavior	1/100(386)
9	GO:0000070	mitotic sister chromatid segregation	1/100(386)
9	GO:0000902	cell morphogenesis	2/100(386)
9	GO:0005783	endoplasmic reticulum	1/100(386)
9	GO:0006355	regulation of transcription, DNA-templated	2/100(386)
9	GO:0002467	germinal center formation	2/100(386)
9	GO:0051015	actin filament binding	1/100(386)
9	GO:0003779	actin binding	6/100(386)
9	GO:0016567	protein ubiquitination	8/100(386)
9	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	1/100(386)
9	GO:0007010	cytoskeleton organization	1/100(386)
9	GO:0031397	negative regulation of protein ubiquitination	2/100(386)
9	GO:2000312	regulation of kainate selective glutamate receptor activity	2/100(386)
9	GO:0004842	ubiquitin-protein transferase activity	4/100(386)
9	GO:0006446	regulation of translational initiation	3/100(386)
9	GO:0042802	identical protein binding	3/100(386)
9	GO:0005615	extracellular space	2/100(386)
894	GO:0003676	nucleic acid binding	2/4(22)
896	GO:0038131	neuregulin receptor activity	1/4(22)
809	GO:0005201	extracellular matrix structural constituent	1/4(24)
9884	GO:0003824	catalytic activity	1/2(3)
353	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	2/8(34)
353	GO:0003677	DNA binding	1/8(34)
9882	GO:0016020	membrane	2/2(3)
9881	GO:0008270	zinc ion binding	1/2(3)
950	GO:0008134	transcription factor binding	2/4(21)
950	GO:0002039	p53 binding	2/4(21)
9920	GO:0070972	protein localization to endoplasmic reticulum	1/2(3)
9921	GO:0007286	spermatid development	1/2(3)
800	GO:0005783	endoplasmic reticulum	1/4(24)
953	GO:0003950	NAD+ ADP-ribosyltransferase activity	2/4(21)
9927	GO:0000149	SNARE binding	1/2(3)
212	GO:0005216	ion channel activity	4/7(49)
955	GO:0030159	receptor signaling complex scaffold activity	1/4(21)
2321	GO:0004175	endopeptidase activity	1/1(12)
2326	GO:0000166	nucleotide binding	4/5(12)
289	GO:0003824	catalytic activity	4/7(40)
4	GO:0001948	glycoprotein binding	1/119(497)
4	GO:0004252	serine-type endopeptidase activity	50/119(497)
4	GO:0004175	endopeptidase activity	2/119(497)
572	GO:0004672	protein kinase activity	2/5(27)
280	GO:0044325	ion channel binding	1/7(40)
285	GO:0005245	voltage-gated calcium channel activity	5/7(40)
1090	GO:0019903	protein phosphatase binding	2/6(19)
1090	GO:0006810	transport	2/6(19)
1092	GO:0030971	receptor tyrosine kinase binding	2/6(19)
1092	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/6(19)
1150	GO:0003779	actin binding	2/2(18)
2499	GO:0005154	epidermal growth factor receptor binding	1/2(11)
2551	GO:0003735	structural constituent of ribosome	2/9(11)
2551	GO:0005737	cytoplasm	1/9(11)
55	GO:0001948	glycoprotein binding	1/29(130)
55	GO:0001764	neuron migration	1/29(130)
55	GO:0002020	protease binding	2/29(130)
55	GO:0007155	cell adhesion	4/29(130)
55	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	1/29(130)
55	GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/29(130)
55	GO:0005112	Notch binding	2/29(130)
55	GO:0030506	ankyrin binding	2/29(130)
54	GO:0000166	nucleotide binding	20/33(131)
57	GO:0000166	nucleotide binding	21/30(129)
2492	GO:0003824	catalytic activity	1/2(11)
51	GO:0048306	calcium-dependent protein binding	2/31(135)
51	GO:0000149	SNARE binding	3/31(135)
51	GO:0006887	exocytosis	1/31(135)
51	GO:0005544	calcium-dependent phospholipid binding	2/31(135)
51	GO:0017158	regulation of calcium ion-dependent exocytosis	1/31(135)
51	GO:0005509	calcium ion binding	4/31(135)
51	GO:0001786	phosphatidylserine binding	1/31(135)
51	GO:0017156	calcium ion regulated exocytosis	1/31(135)
53	GO:0000975	regulatory region DNA binding	1/39(133)
53	GO:0001972	retinoic acid binding	1/39(133)
53	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/39(133)
53	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	6/39(133)
53	GO:0001046	core promoter sequence-specific DNA binding	2/39(133)
53	GO:0003677	DNA binding	9/39(133)
53	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	4/39(133)
53	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	3/39(133)
9950	GO:0044389	ubiquitin-like protein ligase binding	1/2(3)
534	GO:0005089	Rho guanyl-nucleotide exchange factor activity	5/9(28)
2392	GO:0016020	membrane	1/1(12)
532	GO:0016020	membrane	1/6(28)
532	GO:0010468	regulation of gene expression	1/6(28)
531	GO:0005244	voltage-gated ion channel activity	5/6(28)
2257	GO:0000976	transcription regulatory region sequence-specific DNA binding	1/1(13)
2256	GO:0030178	negative regulation of Wnt signaling pathway	1/2(13)
2398	GO:0003676	nucleic acid binding	4/4(12)
538	GO:0004167	dopachrome isomerase activity	2/6(28)
538	GO:0005507	copper ion binding	2/6(28)
538	GO:0004503	monophenol monooxygenase activity	2/6(28)
989	GO:0016020	membrane	1/4(21)
989	GO:0001764	neuron migration	1/4(21)
2473	GO:0046982	protein heterodimerization activity	1/4(11)
2473	GO:0003677	DNA binding	2/4(11)
10328	GO:0006952	defense response	1/1(2)
980	GO:0003779	actin binding	3/4(21)
981	GO:0008013	beta-catenin binding	2/4(21)
985	GO:0043995	histone acetyltransferase activity (H4-K5 specific)	1/4(21)
252	GO:0019992	diacylglycerol binding	4/7(42)
252	GO:0030742	GTP-dependent protein binding	1/7(42)
117	GO:0000287	magnesium ion binding	4/18(77)
117	GO:0001102	RNA polymerase II activating transcription factor binding	2/18(77)
117	GO:0004672	protein kinase activity	7/18(77)
9994	GO:0005216	ion channel activity	2/2(3)
2171	GO:0003824	catalytic activity	4/6(14)
2174	GO:0003735	structural constituent of ribosome	2/2(14)
914	GO:0005102	receptor binding	3/4(22)
916	GO:0008270	zinc ion binding	2/7(22)
425	GO:0008375	acetylglucosaminyltransferase activity	3/5(32)
425	GO:0015020	glucuronosyltransferase activity	1/5(32)
2075	GO:0044822	poly(A) RNA binding	1/2(14)
912	GO:0016020	membrane	4/8(22)
912	GO:0055074	calcium ion homeostasis	1/8(22)
912	GO:0005739	mitochondrion	1/8(22)
309	GO:0016020	membrane	1/7(38)
309	GO:0005086	ARF guanyl-nucleotide exchange factor activity	2/7(38)
2390	GO:0004857	enzyme inhibitor activity	1/2(12)
2602	GO:0003676	nucleic acid binding	1/3(10)
2602	GO:0002151	G-quadruplex RNA binding	1/3(10)
301	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/8(38)
304	GO:0016787	hydrolase activity	5/17(38)
307	GO:0005096	GTPase activator activity	1/6(38)
2647	GO:0035556	intracellular signal transduction	1/3(10)
2647	GO:0046872	metal ion binding	1/3(10)
2677	GO:0042981	regulation of apoptotic process	1/3(10)
2677	GO:0004672	protein kinase activity	1/3(10)
9977	GO:0003824	catalytic activity	1/2(3)
9976	GO:0003676	nucleic acid binding	2/2(3)
9973	GO:0016787	hydrolase activity	1/2(3)
9972	GO:0000123	histone acetyltransferase complex	2/2(3)
9970	GO:0016020	membrane	2/2(3)
9979	GO:0000993	RNA polymerase II core binding	2/2(3)
9978	GO:0016773	phosphotransferase activity, alcohol group as acceptor	2/2(3)
560	GO:0003676	nucleic acid binding	1/5(27)
561	GO:0008430	selenium binding	2/4(27)
2187	GO:0030853	negative regulation of granulocyte differentiation	1/6(14)
2187	GO:0006958	complement activation, classical pathway	2/6(14)
2187	GO:0042803	protein homodimerization activity	1/6(14)
507	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	8/8(29)
226	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3/14(47)
226	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/14(47)
226	GO:0003677	DNA binding	2/14(47)
2777	GO:0004167	dopachrome isomerase activity	1/3(10)
223	GO:0008233	peptidase activity	2/10(48)
223	GO:0004843	thiol-dependent ubiquitin-specific protease activity	2/10(48)
223	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	1/10(48)
222	GO:0005509	calcium ion binding	3/8(48)
221	GO:0004180	carboxypeptidase activity	9/14(48)
2212	GO:0002020	protease binding	2/2(13)
1027	GO:0003824	catalytic activity	4/7(20)
1026	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	4/4(20)
2217	GO:0000166	nucleotide binding	2/2(13)
1023	GO:0008009	chemokine activity	4/8(20)
2363	GO:0005737	cytoplasm	2/2(12)
2219	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/2(13)
1028	GO:0005737	cytoplasm	1/4(20)
1028	GO:0002244	hematopoietic progenitor cell differentiation	1/4(20)
2352	GO:0000166	nucleotide binding	4/5(12)
2350	GO:0016020	membrane	2/5(12)
153	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/13(59)
153	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/13(59)
153	GO:0003676	nucleic acid binding	5/13(59)
601	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/4(26)
601	GO:0003677	DNA binding	1/4(26)
154	GO:0003824	catalytic activity	5/16(59)
154	GO:0003676	nucleic acid binding	4/16(59)
156	GO:0004032	alditol:NADP+ 1-oxidoreductase activity	2/16(59)
156	GO:0016491	oxidoreductase activity	9/16(59)
159	GO:0000166	nucleotide binding	1/9(58)
2431	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1/4(11)
2431	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	1/4(11)
1206	GO:0008289	lipid binding	1/1(18)
959	GO:0051297	centrosome organization	1/7(21)
959	GO:0016020	membrane	1/7(21)
958	GO:0046872	metal ion binding	4/4(21)
49	GO:0003777	microtubule motor activity	11/30(138)
951	GO:0004842	ubiquitin-protein transferase activity	2/4(21)
951	GO:0008270	zinc ion binding	1/4(21)
47	GO:0001085	RNA polymerase II transcription factor binding	2/33(141)
47	GO:0000976	transcription regulatory region sequence-specific DNA binding	2/33(141)
47	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding	4/33(141)
47	GO:0003677	DNA binding	3/33(141)
47	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5/33(141)
47	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/33(141)
44	GO:0004497	monooxygenase activity	26/47(148)
44	GO:0005506	iron ion binding	2/47(148)
42	GO:0005283	sodium:amino acid symporter activity	1/44(151)
42	GO:0005328	neurotransmitter:sodium symporter activity	31/44(151)
42	GO:0005298	proline:sodium symporter activity	2/44(151)
957	GO:0008017	microtubule binding	4/4(21)
41	GO:0000166	nucleotide binding	2/52(151)
41	GO:0004672	protein kinase activity	6/52(151)
1111	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	4/6(19)
1115	GO:0001764	neuron migration	2/6(19)
1115	GO:0000166	nucleotide binding	2/6(19)
1118	GO:0003824	catalytic activity	2/6(19)
1296	GO:0003677	DNA binding	2/2(17)
477	GO:0003779	actin binding	1/4(30)
477	GO:0050699	WW domain binding	2/4(30)
1356	GO:0008417	fucosyltransferase activity	1/2(17)
489	GO:0005783	endoplasmic reticulum	1/10(30)
2007	GO:0016020	membrane	1/2(15)

Node BOP11

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CAFE summary

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