Node summary

Genes15218
Split time44
Descendant nodesTAENIOPYGIA FICEDULA
Ancestral nodeBOP3

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CAFE summary

Expansions16 (2 rapid)
Contractions71 (0 rapid)
Extinctions0

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Family IDGene CountChangeRapid (*)?Exctinction (--)?
9016+1
8761-1
2594-1
25121-1
11501-1
8151-1
11131-1
3182-1
22911-1
10211-1
20121-1
3513-1
20791-1
22771-1
21631-1
10571-1
21581-1
20621-1
22371-1
10311-1
23941-1
18561-1
21761-1
21771-1
12061-1
21111-1
21161-1
19191-1
19101-1
23511-1
17961-1
19911-1
2693-1
23164+1
21501-1
11441-1
3801-1
21901-1
21991-1
16510+1
11201-1
8271-1
1146+1
1052+2
1341+1
1244+1
1731-1
21361-1
14781-1
2531+1
2665+12*
1845-1
20221-1
12451-1
15321-1
3047+1
3225+1
3115-1
21261-1
4421+1
4313+2
22061-1
5020+1
24351-1
19411-1
13971-1
21461-1
21401-1
19201-1
6113-1
7511-1
562+1
23891-1
21691-1
21611-1
789-1
23241-1
23681-1
23611-1
21081-1
21031-1
21021-1
21051-1
15221-1
21201-1
1112+9*
833-1
Family IDGO IDGO term# genes w/ GO ID
1206GO:0008289lipid binding1/1(18)
1522GO:0014065phosphatidylinositol 3-kinase signaling1/2(16)
1920GO:0044822poly(A) RNA binding1/2(15)
61GO:0008284positive regulation of cell proliferation1/24(119)
61GO:0005102receptor binding4/24(119)
61GO:0000904cell morphogenesis involved in differentiation1/24(119)
61GO:0001764neuron migration1/24(119)
61GO:0005201extracellular matrix structural constituent1/24(119)
1910GO:0016020membrane2/2(15)
2199GO:0044822poly(A) RNA binding1/1(13)
25GO:0004930G-protein coupled receptor activity13/66(229)
25GO:0001631cysteinyl leukotriene receptor activity2/66(229)
25GO:0001965G-protein alpha-subunit binding1/66(229)
25GO:0001530lipopolysaccharide binding2/66(229)
25GO:0004871signal transducer activity24/66(229)
26GO:0005200structural constituent of cytoskeleton54/166(216)
2206GO:0000166nucleotide binding1/2(13)
1057GO:0030165PDZ domain binding1/2(19)
44GO:0004497monooxygenase activity26/47(148)
44GO:0005506iron ion binding2/47(148)
1941GO:0003824catalytic activity1/2(15)
1856GO:0008270zinc ion binding1/2(16)
1GO:0001223transcription coactivator binding2/267(729)
1GO:0001077transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding3/267(729)
1GO:0000976transcription regulatory region sequence-specific DNA binding1/267(729)
1GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding6/267(729)
1GO:0003676nucleic acid binding66/267(729)
1GO:0001046core promoter sequence-specific DNA binding1/267(729)
1GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding9/267(729)
1GO:0001078transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding2/267(729)
1GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1/267(729)
1113GO:0006952defense response1/2(19)
5GO:0000287magnesium ion binding2/130(478)
5GO:0000166nucleotide binding70/130(478)
5GO:0004674protein serine/threonine kinase activity1/130(478)
5GO:0004672protein kinase activity10/130(478)
5GO:0046872metal ion binding1/130(478)
5GO:0002039p53 binding2/130(478)
184GO:0000226microtubule cytoskeleton organization1/6(55)
2169GO:0000166nucleotide binding2/2(14)
2158GO:0017056structural constituent of nuclear pore2/2(14)
2361GO:0046872metal ion binding1/2(12)
2012GO:0004871signal transducer activity1/2(15)
2022GO:0008536Ran GTPase binding2/2(15)
83GO:0016020membrane3/5(101)
304GO:0016787hydrolase activity5/17(38)
1150GO:0003779actin binding2/2(18)
1796GO:0003677DNA binding2/2(16)
165GO:0003677DNA binding20/24(57)
78GO:0005216ion channel activity2/14(103)
78GO:0005245voltage-gated calcium channel activity1/14(103)
11GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding9/99(347)
11GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1/99(347)
11GO:0000976transcription regulatory region sequence-specific DNA binding1/99(347)
11GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding3/99(347)
11GO:0003677DNA binding30/99(347)
10GO:0005509calcium ion binding34/114(380)
13GO:0004984olfactory receptor activity3/94(336)
13GO:0004871signal transducer activity31/94(336)
13GO:0003707steroid hormone receptor activity1/94(336)
12GO:0004930G-protein coupled receptor activity6/93(341)
12GO:0004871signal transducer activity51/93(341)
12GO:0001626nociceptin receptor activity2/93(341)
12GO:0001596angiotensin type I receptor activity2/93(341)
12GO:0003779actin binding2/93(341)
12GO:0001965G-protein alpha-subunit binding1/93(341)
12GO:0002020protease binding2/93(341)
1021GO:0003676nucleic acid binding2/2(20)
17GO:0004672protein kinase activity7/57(257)
17GO:0002039p53 binding1/57(257)
17GO:0000166nucleotide binding22/57(257)
32GO:0002020protease binding1/58(170)
32GO:0016525negative regulation of angiogenesis2/58(170)
32GO:0005615extracellular space19/58(170)
32GO:0014068positive regulation of phosphatidylinositol 3-kinase signaling1/58(170)
32GO:0004867serine-type endopeptidase inhibitor activity8/58(170)
31GO:0004252serine-type endopeptidase activity2/24(171)
31GO:0001964startle response2/24(171)
31GO:0016020membrane2/24(171)
31GO:0008344adult locomotory behavior2/24(171)
31GO:0003682chromatin binding1/24(171)
50GO:0055077gap junction hemi-channel activity2/43(137)
50GO:0001568blood vessel development1/43(137)
50GO:0001508action potential1/43(137)
50GO:0004871signal transducer activity2/43(137)
50GO:0002088lens development in camera-type eye1/43(137)
50GO:0007154cell communication12/43(137)
50GO:0005243gap junction channel activity4/43(137)
50GO:0005216ion channel activity2/43(137)
50GO:0042803protein homodimerization activity2/43(137)
2237GO:0005615extracellular space1/1(13)
2146GO:0007165signal transduction2/2(14)
2394GO:0004550nucleoside diphosphate kinase activity2/2(12)
2108GO:0004368glycerol-3-phosphate dehydrogenase activity2/2(14)
1245GO:0016491oxidoreductase activity2/2(17)
1532GO:0006355regulation of transcription, DNA-templated2/2(16)
351GO:0070062extracellular exosome2/5(34)
2103GO:0003700transcription factor activity, sequence-specific DNA binding2/2(14)
2102GO:0005044scavenger receptor activity1/2(14)
827GO:0000386second spliceosomal transesterification activity1/2(23)
2351GO:0048407platelet-derived growth factor binding1/2(12)
90GO:0005198structural molecule activity18/37(97)